Ofloxacin Metronidazole Suspension

Description

Ofloxacin & Metronidazole Oral Suspension (50 mg + 100 mg)

Healthy Inc is a specialized global supplier and exporter of advanced anti-infectives, pediatric medicine, and tropical health therapeutics. We provide ultra-high-purity, kinetically stabilized Ofloxacin & Metronidazole Suspension, manufactured in WHO–GMP certified, high-precision liquid manufacturing facilities. This “Second-Generation Quinolone & Nitroimidazole” combination is a massive-volume strategic export to retail pharmacies, pediatric hospitals, and government health ministries, serving as the globally preferred intervention for severe infectious diarrhea, amoebic dysentery, and mixed gastrointestinal infections in children.

Product Overview

This formulation operates as a “Dual-Phase Intestinal Sterilizer.” It physically targets the DNA integrity of both complex bacteria and parasites to rapidly resolve severe gut infections.

• Mechanism 1 (DNA Gyrase & Topoisomerase IV Inhibition – Ofloxacin): A potent fluoroquinolone that physically enters the bacterial cell to block the enzymes responsible for DNA repair and replication. This leads to the rapid death of a wide range of pathogens, including Shigella, Salmonella, and E. coli.

• Mechanism 2 (Anaerobic DNA Fragmentation – Metronidazole): Physically targets Entamoeba histolytica and Giardia lamblia. It creates toxic intracellular metabolites that cause irreversible DNA strand breakage in anaerobic organisms.

• Mechanism 3 (Enhanced Tissue Penetration): Ofloxacin physically achieves higher concentrations in the intestinal mucosa compared to older quinolones, ensuring faster clinical recovery from deep-seated infections.

Product Composition & Strength

We supply this product as a Sterile, Homogeneous, Micronized Suspension, optimized for stability and high pediatric compliance.

Technical & Logistics Specifications

• HS Code: 3004.20.19 (Medicaments containing other antibiotics / Antiprotozoals)

• CAS Numbers: 82419-36-1 (Ofloxacin) / 443-48-1 (Metronidazole)

• Dosage Form: Oral Liquid (Suspension)

• Packaging: 30ml / 60ml Amber PET Bottles with child-resistant caps. Our specialized packaging ensures 36-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Micronized Homogenization: Both Ofloxacin and Metronidazole Benzoate are physically insoluble. Our manufacturing process utilizes High-Shear Homogenization to ensure a perfectly smooth suspension, preventing “grittiness” and ensuring an exact dose in every spoon.

• Benzoate Advantage: We utilize the Metronidazole Benzoate form, which is physically less bitter than the base, significantly increasing compliance in pediatric patients.

• Aseptic Filling: We utilize Automated Liquid Filling Lines with 100% microbial testing to ensure total safety for children with compromised gastrointestinal health.

Primary Indications

• Pediatrics: Treatment of Severe Infectious Diarrhea and Amoebic Dysentery (bloody stools).

• Tropical Medicine: Management of Giardiasis and mixed intestinal infections resistant to first-line agents.

• Gastrology: Relief of severe abdominal cramps and frequent loose motions associated with infection.

• Public Health: Second-line intervention for localized outbreaks of bacterial enteritis.

Dosage & Administration

• Children (2-5 years): Typically 5ml (one teaspoon) twice daily for 3 to 5 days.

• Children (6-12 years): Typically 10ml twice daily for 3 to 5 days.

• Administration: For maximum safety and to reduce potential gastric upset, it should physically be taken 1 hour before or 2 hours after food.

• Shake Well: The bottle must be physically shaken before each use to ensure both active components are evenly distributed.

Safety Warning: For Oral Use Only. Alcohol Warning: Strictly avoid alcohol during and for 48 hours after treatment (Disulfiram-like reaction). Tendon Note: While rare in children, Ofloxacin use should be physically monitored for any joint or tendon pain. Contraindication: Do not use in patients with a history of hypersensitivity to Quinolones or Nitroimidazoles.

Global Export & Contract Manufacturing

Healthy Inc is a premier Anti-Infective and Pediatric Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume anti-diarrheal suspensions. Whether you are a National Health Tender in the CIS or a B2B Pharma Marketplace partner in Africa or SE Asia, we ensure secure, WHO-GMP compliant delivery.