Description
Norfloxacin Tablets (400 mg)
Healthy Inc is a specialized global supplier of high-stability fluoroquinolone anti-infectives. We provide premium Norfloxacin Tablets, manufactured in WHO–GMP certified antimicrobial units. As a frontline treatment for urogenital and enteric infections, this product is a primary export for urology clinics, gastroenterology centers, and Ministry of Health (MOH) tenders in Southeast Asia, Africa, and Latin America.
Product Overview
Norfloxacin is a synthetic, broad-spectrum antibacterial agent. It belongs to the first generation of fluoroquinolones and is specifically engineered to provide high inhibitory concentrations in the urine and digestive tract, making it exceptionally effective against gram-negative pathogens.
The “Urogenital & Enteric” Specialist:
- Mechanism of Action: Norfloxacin exerts its bactericidal effect by inhibiting DNA gyrase (Topoisomerase II) and Topoisomerase IV. These enzymes are essential for bacterial DNA replication, transcription, and repair. By blocking them, Norfloxacin causes irreversible damage to bacterial DNA, leading to rapid cell death.
- Localized Potency: Unlike systemic fluoroquinolones, Norfloxacin achieves its highest concentrations in the renal system and the intestinal lumen. This localization ensures maximum efficacy at the site of infection with reduced systemic exposure.
- Broad Pathogen Coverage: It is highly active against common UTI pathogens including E. coli, Klebsiella, and Proteus, as well as enteric pathogens like Shigella and Salmonella.
Technical & Manufacturing Specifications
Formulated for rapid disintegration and optimized drug release in specialized environments.
| Technical Metric | Specification Standard |
|---|---|
| Active Ingredient | Norfloxacin BP / USP / IP |
| Dosage Form | Film-Coated Tablets |
| Standard Strength | 400 mg |
| HS Code | 3004.20.19 (Other Antibiotics) / 2933.59.90 |
| Packaging | Alu-Alu Blister or PVC-PVDC Blister Pack |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from ISO 9001:2015 certified units.
- Photosensitivity Protection: Norfloxacin is sensitive to UV light. Our tablets are protected by an opaque film coating and secondary packaging designed to prevent photodegradation during transit to tropical climates.
- Crystallinity & Dissolution Control: We maintain strict control over the API particle size to ensure rapid dissolution ($>80$% in 30 minutes), which is vital for achieving rapid therapeutic levels in the urinary tract.
- Stability Validation: Every batch is validated for Climatic Zone IVb, ensuring the product remains chemically stable and microbiologically potent in high-humidity export markets.
Therapeutic Indications & Clinical Symptoms
- Urinary Tract Infections (UTIs): Treatment of both complicated and uncomplicated cystitis, pyelitis, and cystopyelitis.
- Prostatitis: Management of acute or chronic inflammation of the prostate caused by susceptible bacteria.
- Gastroenteritis: Treatment of acute bacterial diarrhea and “Traveler’s Diarrhea.”
- Gonorrhea: Management of uncomplicated urethral and endocervical gonorrhea.
Dosage & Administration
- UTI Dose: 400 mg twice daily for 3 to 10 days depending on severity.
- Administration: Should be taken 1 hour before or 2 hours after a meal with a full glass of water.
- Safety Note: Patients should maintain adequate hydration to prevent crystalluria. Avoid co-administration with antacids containing magnesium or aluminum, as they significantly reduce absorption.
Global Export & Contract Manufacturing Services
Healthy Inc is a verified Pharmaceutical Exporter in Mumbai, catering to NGO Health Missions and Ministry of Health Tenders. We offer Third Party Manufacturing for Norfloxacin with full CTD Dossier and COPP support. Our logistics network ensures secure, high-volume supply to Nigeria, Vietnam, Kenya, and Brazil, providing WHO-GMP quality at competitive B2B prices.
Commercial Inquiries
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
