Description
Niacinamide (Vitamin B3) Premium Skin-Defense Tablets (500 mg)
Healthy Inc is a specialized global supplier and exporter of advanced dermatological, nutri-cosmetic, and aesthetic support therapeutics. We provide ultra-high-purity, kinetically stabilized Niacinamide Film-Coated Tablets (500 mg), manufactured in WHO–GMP certified, high-precision oral solid dosage facilities. This “Cellular Skin-Barrier & Anti-Inflammatory Precursor” is a massive-volume, highly lucrative export to aesthetic dermatology clinics, premium OTC beauty networks, anti-aging centers, and private pharmacy chains in LATAM, the CIS, Africa, and Southeast Asia, serving as the globally mandated, high-compliance oral intervention for severe Acne Vulgaris, Melasma, and epidermal barrier dysfunction.
Product Overview
This highly advanced systemic formulation delivers a massive, clinically proven dose of the active amide form of Vitamin B3, working from the inside out to fundamentally restructure the skin’s defense matrix and shut down the inflammatory cascades driving cystic acne.
The “Ceramide-Boosting & Sebum-Regulating” Specialist:
- Mechanism 1 (The Sebum & Inflammatory Blockade): For patients suffering from severe, inflammatory acne who cannot tolerate aggressive oral retinoids (like Isotretinoin) or systemic antibiotics, oral Niacinamide is the ultimate rescue therapy. It actively suppresses the production of pro-inflammatory cytokines (like IL-6) and forcefully downregulates the sebaceous glands, drastically reducing the oil production that feeds acne-causing bacteria.
- Mechanism 2 (Melanosome Transfer Inhibition): In patients dealing with severe hyperpigmentation, Melasma, or dark acne scars, topical creams frequently fail to penetrate deep enough. Systemic Niacinamide physically blocks the transfer of melanin pigment (melanosomes) from the melanocytes to the surrounding skin cells (keratinocytes), actively fading dark spots and radically brightening the overall complexion from within.
- Mechanism 3 (Epidermal Ceramide Synthesis): Niacinamide acts as a direct catalyst for the synthesis of ceramides and free fatty acids in the skin. By rapidly rebuilding the skin’s lipid barrier, it locks in systemic moisture and protects the dermis from environmental pollutants, making it a highly sought-after systemic anti-aging and hydration therapy.
Product Composition & Strength
We supply this product as a Precision-Blended, High-Purity Tablet, packed exclusively in highly secure, premium Alu-PVC blister strips or high-density HDPE aesthetic bottles to ensure the absolute chemical stability of the vitamin matrix.
| Active Ingredient | Strength | Primary Clinical Function |
|---|---|---|
| Niacinamide (Vitamin B3) USP/Ph.Eur. | 500 mg | Global Premium Dermatology Standard: High-dose adult therapy for systemic acne control, anti-aging ceramide synthesis, and hyperpigmentation reduction. |
| Excipients | Microcrystalline Cellulose / Croscarmellose Sodium / Stearic Acid / Magnesium Stearate / Premium Opadry Film | Diluent / Superdisintegrant / Lubricant (Engineered specifically for rapid gastric dissolution to ensure peak systemic saturation and rapid delivery to the dermal layers) |
*Pack Sizes: 10×10 Blisters or Bottles of 60/100 (Optimized specifically for premium OTC retail and daily dermatological regimens).
Technical & Logistics Specifications
Critical data for Nutri-Cosmetic Importers, Aesthetic Distributors, and Retail Pharmacy Chains.
| HS Code | 3004.50.90 (Medicaments containing vitamins or derivatives – Dermatologicals) |
| CAS Number | 98-92-0 (Niacinamide) |
| Dosage Form | Film-Coated Tablet (Immediate Release) |
| Packaging | Premium Alu-PVC Blisters or Aesthetic HDPE Bottles. Protects the formulation from environmental humidity, preventing vitamin degradation. |
| Storage | Store strictly below 30°C in a dry place. Protect heavily from Moisture. |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Cosmetic-Grade Purity & “No-Flush” Engineering: Discerning aesthetic patients will abandon a product immediately if it causes adverse reactions. If Niacinamide is manufactured poorly, it hydrolyzes into Niacin, causing a violent, painful full-body hot flush. Our facilities utilize strict, climate-controlled dry blending to ensure the amide bond remains 100% stable. We guarantee a pharmaceutical-grade, pure Niacinamide yield that delivers massive skin benefits with zero flushing or burning, protecting your brand’s premium reputation.
Therapeutic & Aesthetic Indications
Indicated for the systemic, inside-out management of dermatological conditions:
- Inflammatory Acne Vulgaris: Powerful oral adjunct to reduce cysts, papules, and systemic facial redness.
- Hyperpigmentation & Melasma: Systemic blockade of melanosome transfer to brighten and even skin tone.
- Skin Barrier Dysfunction: Upregulation of epidermal ceramides to treat chronic dryness and Rosacea.
- Anti-Aging & Photo-Damage: Cellular ATP replenishment to combat fine lines and UV-induced oxidative stress.
Dosage & Administration
Recommended Dosage (Strictly as per Dermatologist/Aesthetician Guidelines):
- Standard Adult Dosing: 500 mg taken orally once or twice daily.
- Administration: Can be taken with or without food. Taking with meals can drastically reduce mild gastrointestinal upset, which is the most common side effect of mega-dose vitamin therapy.
Safety Warnings (CRITICAL Regulatory & Clinical Data):
- The Lipid-Lowering Fallacy: Patients must understand that Niacinamide does not lower cholesterol. It must not be substituted for Niacin in cardiovascular patients.
- Hepatic Load: While incredibly safe compared to systemic retinoids or antibiotics, mega-doses of Niacinamide (exceeding 3,000 mg/day) can elevate liver enzymes.
- Gastrointestinal Distress: High doses on an empty stomach may cause nausea or mild diarrhea.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving international Cosmeceutical Brands, Dermatology Networks, and Private Label Retailers. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Nutri-Cosmetics and Premium Dermatological Supplements. Whether you are looking for a reliable Private Label Supplier for beauty chains in Southeast Asia or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely, secure delivery of highly stable, WHO-GMP certified products.









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