Metoclopramide Hydrochloride Drops

Description

Metoclopramide Hydrochloride Oral Drops (5 mg / ml)

Healthy Inc is a specialized global supplier and exporter of advanced gastroenterology, pediatric medicine, and critical-care therapeutics. We provide ultra-high-purity, kinetically stable Metoclopramide Drops, manufactured in WHO–GMP certified, high-precision liquid manufacturing facilities. This “Dopamine Receptor Antagonist & Prokinetic” is a strategic export to retail pharmacies, pediatric hospitals, and government health ministries, serving as the globally preferred intervention for severe nausea, vomiting, and gastric stasis in infants and children.

Product Overview

This formulation operates as a “Dual-Action Digestive Catalyst.” It physically coordinates the movement of the upper digestive tract while chemically silencing the neurological signals that trigger vomiting.

• Mechanism 1 (Central Anti-Emetic): Metoclopramide physically crosses the blood-brain barrier to block Dopamine ($D_{2}$) and Serotonin ($5\text{-}HT_{3}$) receptors in the Chemoreceptor Trigger Zone (CTZ).

• Mechanism 2 (Peripheral Prokinetic): It physically increases the resting tone of the Lower Esophageal Sphincter (LES) and increases the amplitude of upper GI contractions.

• Mechanism 3 (Gastric Emptying): By physically relaxing the pyloric sphincter and increasing duodenal peristalsis, it chemically ensures that stomach contents move downward rapidly, preventing reflux and vomiting.

Product Composition & Strength

We supply this product as a Sterile, Clear, Concentrated Solution, optimized for drop-by-drop pediatric precision.

Technical & Logistics Specifications

• HS Code: 3004.90.99 (Medicaments acting on the digestive system / Others)

• CAS Number: 54143-57-4 (Metoclopramide Hydrochloride)

• Dosage Form: Oral Liquid Drops

• Packaging: 10 ml / 15 ml / 30 ml Amber Glass Bottles with calibrated dropper assemblies. Our specialized packaging ensures 36-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Aseptic Precision Filling: Our manufacturing process utilizes Automated Drop-Filling Lines with 100% microbial testing to ensure total safety for neonatal and pediatric populations.

• Light-Sensitive Protection: Metoclopramide is physically sensitive to light. We utilize USP Type-III Amber Glass and specialized outer cartons to prevent drug photodegradation.

• Low-Volume Precision: We ensure a consistent physical viscosity to guarantee that each “drop” delivered by the calibrated assembly contains the exact micro-dose required for infants.

Primary Indications

• Pediatrics: Management of Severe Gastroesophageal Reflux (GERD) unresponsive to other treatments.

• Surgery: Prevention and treatment of Post-Operative Nausea and Vomiting (PONV).

• Gastrology: Treatment of Gastroparesis (delayed gastric emptying) associated with systemic conditions.

• Radiology: Facilitating small bowel intubation or accelerating gastric emptying during barium studies.

Dosage & Administration

• Standard Regimen: Typically 0.1 mg/kg to 0.15 mg/kg body weight per dose, administered 3 times daily.

• Administration: Drops should physically be administered 30 minutes before feeding for maximum prokinetic effect.

• Short-Term Use: It is physically recommended for short-term use (maximum 5 days) to minimize neurological risks.

Safety Warning: For Oral Use Only. Neurological Note: Physicians must physically monitor for Extrapyramidal Symptoms (EPS) (involuntary muscle movements), especially in children. Tardive Dyskinesia Risk: Avoid high doses or prolonged use beyond 12 weeks. Contraindication: Do not use in patients with gastrointestinal hemorrhage, mechanical obstruction, perforation, or a history of seizure disorders.

Global Export & Contract Manufacturing

Healthy Inc is a premier Gastroenterology and Pediatric Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume Metoclopramide drops. Whether you are a National Pediatric Hospital in the CIS or a B2B Pharma Marketplace partner in Africa or Southeast Asia, we ensure secure, WHO-GMP compliant delivery.