Description
Mebendazole Tablets (100 mg / 500 mg)
Healthy Inc is a premier global provider of high-efficacy anti-parasitic therapies. We provide premium Mebendazole Tablets, manufactured in WHO–GMP certified specialized anthelmintic production units. As a frontline treatment for single or mixed intestinal worm infestations, this product is a vital export for pediatric clinics, school deworming programs, and Ministry of Health (MOH) tenders in Southeast Asia, Africa, and Latin America.
Product Overview
Mebendazole is a synthetic benzimidazole derivative with a broad spectrum of anthelmintic activity. It is specifically engineered to target intestinal parasites locally while maintaining low systemic absorption, ensuring maximum lethal impact on worms with minimal side effects for the host.
The “Total Deworming” Specialist:
- Mechanism of Action: Mebendazole selectively and irreversibly inhibits the formation of helminth microtubules by binding to viral tubulin. This leads to the depletion of glycogen stores and inhibits glucose uptake in the parasite, effectively starving the worm and causing its death.
- Broad Spectrum Efficacy: It is highly effective against the most common “Soil-Transmitted Helminths” (STH), including Ascaris lumbricoides (Roundworm), Trichuris trichiura (Whipworm), Enterobius vermicularis (Pinworm), and Hookworms.
- Localized Intestinal Action: Due to its poor solubility, approximately 90% of the drug remains in the gastrointestinal tract, ensuring high concentrations at the site of infection.
Technical & Manufacturing Specifications
Formulated for effective disintegration and standardized intestinal transit.
| Technical Metric | Specification Standard |
|---|---|
| Active Ingredient | Mebendazole BP / USP / IP |
| Dosage Form | Chewable / Immediate Release Tablets |
| Available Strengths | 100 mg, 500 mg (WHO Single-Dose Standard) |
| HS Code | 3004.90.99 (Anthelmintics) / 2933.99.00 |
| Packaging | Blister (PVC-Alu) or Bulk Packs for Mass Deworming |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from ISO 9001:2015 certified units.
- Chewable Tablet Optimization: To facilitate administration in pediatric populations, we offer flavored chewable tablets that do not require water, increasing compliance in rural and school-based settings.
- Particle Size Control: We utilize specialized micronization to ensure that the poorly soluble Mebendazole particles are evenly distributed, maximizing the surface area available to interact with the parasite’s intestinal lining.
- Stability Validation: Validated for Zone IVb climates. Our tablets are designed to remain chemically stable for 36 months in high-heat and high-humidity tropical regions.
Therapeutic Indications & Clinical Symptoms
- Ascariasis: Treatment of large roundworm infections.
- Enterobiasis (Pinworm): Elimination of threadworms, often requiring a second dose after two weeks to prevent reinfection.
- Hookworm & Whipworm: Effective management of Ancylostoma and Trichuris infestations.
- Mass Drug Administration (MDA): The 500 mg single-dose is the global standard for preventative chemotherapy in high-risk endemic areas.
Dosage & Administration
- Standard Infection (Pinworm): A single 100 mg dose, often repeated in 2-3 weeks.
- Mixed/Heavy Infestations: 100 mg twice daily for 3 consecutive days.
- Mass Deworming: A single 500 mg dose administered periodically (every 6-12 months).
- Safety Note: Contraindicated during the first trimester of pregnancy. No special procedures such as fasting or purging are required.
Global Export & Contract Manufacturing Services
Healthy Inc is a verified Anthelmintic Exporter in Mumbai, catering to NGO Health Missions and Ministry of Health Tenders. We offer Third Party Manufacturing for Mebendazole with full CTD Dossier and COPP support. Our logistics network ensures secure transit to Nigeria, Ethiopia, Vietnam, and Brazil, providing WHO-GMP quality at competitive B2B prices.
