Description
Levamisole Tablets
Levamisole Hydrochloride Tablets USP / BP / IP (50 mg / 150 mg)
Imidazothiazole Anthelmintic & Immunomodulatory Therapeutics
Healthy Life Pharma Private Limited, alongside our specialized global export and marketing division Healthy Inc, is a premier Indian manufacturer, CDMO partner, and wholesale exporter of advanced tropical medicines, anti-parasitics, and essential public health formulations. We manufacture ultra-high-purity, kinetically stable Levamisole Hydrochloride Tablets inside our state-of-the-art, WHO–GMP certified solid dosage manufacturing installations.
Serving as a core therapeutic baseline for mass deworming programs and immune optimization protocols, this product represents a high-velocity strategic export to national health ministries, public hospital networks, global humanitarian relief pipelines, and digital B2B pharmaceutical marketplaces across Sub-Saharan Africa, the CIS region, LATAM, and South-East Asia.
Product Overview
This formulation operates as a “Nematode Neuromuscular Depolarizing Agent.” It ensures immediate parasite clearance by inducing neuromuscular paralysis in target helminths, forcing them to detach from the host tissues and pass safely out of the system.
Mechanism 1 (Nicotinic Acetylcholine Receptor Agonism): Levamisole physically enters the parasite’s matrix and acts as a powerful nicotinic acetylcholine receptor agonist directly on the nematode’s muscle cell membranes.
Mechanism 2 (Spastic Neuromuscular Paralysis): This binding chemically induces a state of persistent, un-gated depolarization across the parasite’s neuromuscular junction. This physically triggers an immediate, continuous muscular contraction, locking the worm into a state of spastic paralysis.
Mechanism 3 (Rapid Expulsion & Immunomodulation): The paralyzed worms lose their physical ability to hold onto or migrate against the host’s intestinal wall. They are detached and physically flushed out of the gastrointestinal lumen via normal peristalsis within 24 hours. Concurrently, in host biology, it chemically restores T-lymphocyte and macrophage cellular function to baseline when the immune system is depressed.
Product Composition & Available Strengths
We supply Levamisole Hydrochloride across the two primary compendial configurations required to execute precise pediatric deworming courses or adult high-mass therapeutic maintenance.
| Active Ingredient Monograph | Available Strengths | Formulation Matrix Delivery System | Primary Clinical Application |
| Levamisole Hydrochloride USP / BP / IP | 50 mg | Oral Solid Uncoated / Chewable Tablet | Pediatric Deworming & Titration: Low-dose format calibrated for exact mass titration in pediatric ascariasis or low-dose immunomodulatory courses. |
| Levamisole Hydrochloride USP / BP / IP | 150 mg | Oral Solid Compressed Tablet | The Core Commercial Volume: High-potency, single-dose adult baseline format optimized for rapid mass community deworming campaigns. |
Technical & Logistics Specifications
HS Code: 3004.90.99 (Medicaments acting on parasitic diseases / Anthelmintics / Imidazothiazoles)
CAS Number: 16595-80-5 (Levamisole Hydrochloride) / 14769-73-4 (Levamisole Base)
Dosage Form: Oral Solid Tablet (Engineered with deep-set score lines to support quick, safe dosage fractioning for pediatric cohorts)
Packaging Configurations:
Retail Blisters: 1 / 2 / 10 Tablets per Blister Strip packed in high-barrier Alu-Alu (Cold-Form Foil) or silver PVC/PVDC matrix strips.
Institutional Tenders: Bulk packs of 100 / 500 / 1000 Tablets per induction-sealed HDPE Bottle to maximize shipping efficiency and lower unit freight costs for national ministries. Our tropicalized packaging matrices completely isolate the active core, guaranteeing a full 36-month shelf life in hot, humid Zone IVb export environments.
Advanced Manufacturing Integrity & Quality Controls
High-Velocity Bulk Compression Precision: To comfortably satisfy multi-million unit public health tender deadlines and emergency NGO relief shipments, we utilize high-output rotary tableting lines equipped with Automated Forced-Feeder Die Matrices and Online Weight Variation Regulators, physically ensuring absolute mass and content uniformity.
Low Moisture Blending Stability: Levamisole Hydrochloride is a highly crystalline powder that requires absolute dry processing to prevent core chipping. We execute our complete mixing, dry granulation, and tableting runs within Climate-Controlled Processing Blocks with relative humidity strictly held below 40%, preserving baseline crystalline stability.
Validated Rapid Disintegration Kinetics: Every single export production batch physically undergoes Automated In-Vitro Dissolution Profiling, chemically verifying that our compressed tablets achieve immediate disintegration (under 5 minutes), ensuring rapid systemic release and fast clinical parasite intervention.
Primary Indications
Tropical Medicine & Helminthology: First-line, fast-acting treatment of infestations caused by Ascaris lumbricoides (Common Roundworm) and Ancylostoma duodenale (Hookworm).
Immunology Adjuvant: Adjuvant medical management of specific immunodeficient states, aphthous stomatitis, and as an adjunct in colorectal cancer post-surgical regimens (under specific co-prescribed protocols).
Usage Instructions
The Single-Dose Eradication Protocol: For standard ascariasis deworming, the medication is administered physically as a single dose, preferably taken with a light meal. The single-dose matrix ensures 100% patient compliance without requiring multi-day monitoring.
The Synchronization Protocol: Because parasitic roundworms transmit rapidly through shared environments and household contacts, it is clinically recommended to treat all members of a family or school cluster simultaneously to physically close the door on reinfection cycles.
Hematological Tracking Requirement: When Levamisole is utilized over long periods at higher doses for immunomodulatory indications, regular tracking of Complete Blood Counts (CBC) is clinically recommended to monitor for rare reversible leukopenia.
Safety Warning: POTENT IMIDAZOTHIAZOLE ANTIPARASITIC & IMMUNOMODULATOR. For Professional Medical Supervision and Programmatic Guidelines Only. Pediatric Safety Note: Ensure precise milligram tracking based on body weight ($3.0\,\text{mg/kg}$) when administering the 50 mg format to pediatric networks; do not exceed calculated therapeutic ceilings. Alcohol Interaction Caution: Advise patients to strictly avoid alcohol consumption during and for 24 hours post-treatment, as Levamisole can chemically induce a disulfiram-like reaction characterized by flushing, nausea, and tachycardia. Contraindications: Absolute contraindications in patients presenting with pre-existing severe blood dyscrasias (like advanced neutropenia), severe renal or hepatic failure, pregnancy, or known hypersensitivity to imidazothiazole matrices.
Global CDMO Services & Wholesale Tender Supply
Healthy Life Pharma Private Limited and Healthy Inc provide comprehensive, internationally validated Third-Party Contract Manufacturing (CDMO Services) and bulk private-label export pipelines for the entire Levamisole Hydrochloride portfolio. Because this molecule faces zero controlled-substance dual-licensing regulatory hurdles, our high-capacity lines can rapidly manufacture, release, and ship multi-container shipping loads. We handle all mandatory documentation (WHO-GMP Certificate, Certificates of Pharmaceutical Product – COPP, Certificates of Analysis – COA, Stability Testing Matrix Sheets, and Complete CTD Format Dossier sets) for rapid entry registration.
Commercial & Bulk Procurement Inquiries:
Corporate Head Office: Mumbai, Maharashtra, India
Primary Manufacturing Base: Boisar, Maharashtra, India
WhatsApp / Direct Call: +91 7710003340
Corporate Email: info@healthyinc.co.in
