Itraconazole cream

Description

Itraconazole Cream (1.0% w/w)

Healthy Inc is a specialized global supplier and exporter of advanced dermatology, anti-infectives, and targeted fungal therapeutics. We provide ultra-high-purity, kinetically balanced Itraconazole Cream, manufactured in WHO–GMP certified, high-precision specialized topical facilities. This “Triazole Antifungal Agent” is a strategic export to retail pharmacies, dermatology clinics, and premium healthcare providers, serving as a potent intervention for superficial dermatomycoses that require high-affinity binding.

Product Overview

This formulation operates as a “Sterol Synthesis Blocker.” It is specifically engineered to have a high affinity for the keratinized tissues of the skin, providing a sustained antifungal environment.

• Mechanism 1 (Lanosterol Demethylase Inhibition): Itraconazole inhibits the fungal cytochrome P450-dependent enzyme, Lanosterol 14α-demethylase. This physically blocks the conversion of lanosterol to ergosterol.

• Mechanism 2 (Cellular Membrane Porosity): The depletion of ergosterol physically disrupts the fungal cell membrane structure. This leads to the leakage of internal cellular components and subsequent cell death.

• Mechanism 3 (Lipophilic Reservoir): Due to its highly lipophilic nature, the cream creates a “reservoir” in the Stratum Corneum. This physically ensures the medicine remains active in the skin layers even after the application stops.

Product Composition & Strength

We supply this product in a Smooth, High-Spreadability Emulsion, optimized for deep penetration into thickened skin.

Technical & Logistics Specifications

• HS Code: 3004.20.19 (Medicaments containing other antibiotics – Antifungals)

• CAS Number: 84625-61-6 (Itraconazole)

• Dosage Form: Topical Cream (O/W Emulsion)

• Packaging: Laminated Aluminum or Plastic Tubes (15g / 30g / 50g). Our high-barrier packaging ensures 24-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Micronization Excellence: Our manufacturing process utilizes Fluid Energy Milling to ensure Itraconazole particles are ultra-fine. This is critical because Itraconazole is naturally poorly soluble; micronization physically increases the surface area for maximum absorption.

• Homogenization Standards: We utilize Vacuum-Aided Emulsifiers to ensure a perfectly uniform distribution of the API, preventing “crystallization” within the tube during long-distance exports.

Primary Indications

• Dermatology: Treatment of Tinea Corporis (Body Ringworm), Tinea Cruris (Jock Itch), and Tinea Pedis (Athlete’s Foot).

• Infectious Disease: Management of Pityriasis Versicolor (fungal skin patches) and Cutaneous Candidiasis.

• Specialist Care: Used for fungal infections of the skin that have shown poor response to traditional Imidazoles (like Clotrimazole).

Dosage & Administration

• Standard Regimen: Apply a thin layer to the affected area once or twice daily.

• Duration: Usually 2 to 4 weeks depending on the severity and site of infection.

• Note: Keep the affected area dry and clean during treatment to accelerate healing.

Safety Warning: External Use Only. Avoid contact with eyes and mucous membranes. Irritation: If severe irritation or a rash develops, discontinue use immediately. Contraindication: Do not use if known hypersensitivity to triazole antifungals exists.

Global Export & Contract Manufacturing

Healthy Inc is a premier Dermatology and Antifungal Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume, specialized topicals. Whether you are a Pharmacy Chain in Africa or a B2B Pharma Marketplace partner in the CIS or LATAM, we ensure secure, WHO-GMP compliant delivery.

Commercial Inquiries:

WhatsApp/Call: +91 7710003340

Email: info@healthyinc.co.in