Description

Iron Sucrose Injection

Healthy Inc is a specialized global supplier and exporter of advanced parenteral iron therapies. We provide high-purity Iron Sucrose Injection (100 mg / 5 ml), sourced from WHO–GMP certified sterile injectable facilities. This “Hematinic Powerhouse” is a top export to nephrology dialysis centers, maternity wards, and government health ministries in Africa, LATAM, and Southeast Asia, serving as the gold standard for treating Iron Deficiency Anemia (IDA) in Chronic Kidney Disease (CKD) and Pregnancy, with a significantly lower risk of anaphylaxis compared to older iron dextran formulations.

Product Overview

This formulation contains Iron (III) Hydroxide Sucrose Complex, a colloidal solution of polynuclear iron-hydroxide cores surrounded by sucrose molecules.

The “Safe Iron” Specialist:

• Mechanism (The “Controlled Release”): Unlike simple iron salts, Iron Sucrose is a complex. Upon injection, it is taken up by the Reticuloendothelial System (RES) in the liver and spleen. The sucrose shell is broken down, and the iron is slowly released to bind with Transferrin, which transports it to the bone marrow for Red Blood Cell production. This controlled release prevents “Free Iron Toxicity.”
• Dialysis Standard: It is the primary choice for CKD patients on Hemodialysis who require Erythropoietin (EPO), as EPO cannot work without adequate iron stores.
• Pregnancy Safety: It is the preferred IV iron for severe anemia in the 2nd and 3rd trimesters when oral iron is ineffective or not tolerated.

Product Composition & Strength

We supply this product as a Sterile Dark Brown Solution in Glass Ampoules.

*Pack Sizes: Tray of 5 Ampoules or 10 Ampoules.

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Molecular Weight Control: The safety of Iron Sucrose depends on its molecular weight (Mw 34,000 – 60,000 Daltons). If the Mw is too low, “labile iron” is released causing toxicity; if too high, it causes allergic reactions. Our manufacturing process uses Gel Permeation Chromatography (GPC) to ensure the molecular weight distribution is identical to the innovator, ensuring safety.
• Alkalinity: The solution is highly alkaline (pH ~10.5). We use specialized glass and stoppers that resist alkali attack to prevent “flaking” or leaching during storage.

Therapeutic Indications (Human Use)

Indicated for the treatment of iron deficiency anemia in:

• Chronic Kidney Disease (CKD): Non-dialysis-dependent and Hemodialysis-dependent patients.
• Pregnancy: 2nd and 3rd Trimester (Severe Anemia).
• Post-Partum: Rapid replenishment after delivery hemorrhage.
• Malabsorption: Patients with IBD (Crohn’s/Ulcerative Colitis) or after Gastric Bypass surgery.

Dosage & Administration

Recommended Dosage (Strictly as per Hematologist):

• Route: Slow Intravenous (IV) Injection or Infusion ONLY.
• Standard Dose: 100 mg to 200 mg (1-2 ampoules) per session.
• Frequency: 1 to 3 times a week until total iron deficit is corrected (Calculate using Ganzoni Formula).
• Administration:
  • Slow Injection: 100 mg over 2-5 minutes (undiluted).
  • Infusion: Dilute 100 mg in max 100 ml Saline. Infuse over 15 minutes. (Do not dilute in large volumes or Dextrose).

Safety Warnings (CRITICAL):

• NEVER INTRAMUSCULAR (IM): ABSOLUTE CONTRAINDICATION. IM injection causes permanent brown staining (tattooing) of the skin, severe pain, and potential sarcoma risk. IV Use Only.
• Hypotension: Rapid injection causes a sudden drop in blood pressure. Inject slowly.
• Iron Overload: Monitor Serum Ferritin. Do not use if Ferritin > 500-800 ng/ml (Risk of hemosiderosis).
• Extravasation: Leakage outside the vein causes long-lasting skin discoloration. Ensure the needle is in the vein.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Sterile Injectables, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.