Description

Gabapentin Capsules

Healthy Inc is a specialized global supplier and exporter of advanced neurological, orthopedic, and psychiatric therapeutics. We provide high-purity, therapeutically dosed Gabapentin Capsules (100 mg / 300 mg / 400 mg), manufactured in WHO–GMP certified, high-capacity oral solid dosage facilities. This “Foundational Alpha-2-Delta Ligand” is a massive-volume, essential export to neurology centers, diabetic clinics, pain management hospitals, and government health ministries in LATAM, the Middle East, Africa, and Southeast Asia, serving as the globally trusted, first-line intervention for post-herpetic neuralgia, severe peripheral neuropathy, and partial-onset seizures.

Product Overview

This formulation contains Gabapentin, a highly stable structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), designed to actively quiet a hyper-aroused central nervous system.

The “Foundational Nerve Pain & Seizure” Specialist:

• Mechanism (Calcium Channel Blockade): Despite its structural similarity to GABA, Gabapentin does not bind to GABA receptors. Instead, it binds with high affinity to the alpha-2-delta subunit of voltage-gated calcium channels. By physically blocking the influx of calcium into hyperactive neurons, it forcefully suppresses the release of excitatory neurotransmitters (glutamate, norepinephrine, and substance P) that transmit pain and trigger seizures.
• The Neuropathy Gold Standard: Traditional painkillers (NSAIDs, Paracetamol) are entirely ineffective against nerve damage. Gabapentin rapidly halts the burning, shooting, and electric-shock sensations characteristic of damaged nerves, making it the global cornerstone for treating Diabetic Peripheral Neuropathy and the agonizing lingering pain of Shingles (Post-Herpetic Neuralgia).
• The High-Volume Adherence Advantage: Because Gabapentin has been off-patent longer and generally faces fewer aggressive controlled-substance import restrictions than newer gabapentinoids in many African and LATAM regions, it remains the most highly procured, cost-effective neuromodulator for population-level public health tenders.

Product Composition & Strength

We supply this product as a Hard Gelatin Capsule, packed in highly secure, moisture-resistant Alu-PVC or opaque Alu-Alu blister strips to ensure API stability and rapid gastric dispersion.

*Pack Sizes: 10×10 or 10×15 Blisters (Optimized for 30-day chronic neurology dispensing and high-dose, multi-capsule daily regimens).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Neurology Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• High-Dose Blending Engineering: Formulating 300mg and 400mg capsules requires accommodating a massive volume of active API powder within a standard capsule shell. Our manufacturing utilizes advanced high-shear geometric blending to guarantee perfect powder flow and compressibility, ensuring the capsule doesn’t split and delivers absolute dose uniformity.
• Bioavailability Validation: Because Gabapentin absorption is saturable (absorption decreases as the dose increases), our formulation utilizes specialized superdisintegrants to ensure immediate, total gastric release, maximizing the drug’s interaction with the L-amino acid transport system in the gut.

Therapeutic Indications (Human Use)

Indicated for the comprehensive management of chronic neuropathic and seizure disorders:

• Post-Herpetic Neuralgia (PHN): Management of severe, lingering nerve pain following an outbreak of Herpes Zoster (Shingles) in adults.
• Epilepsy (Partial Seizures): Adjunctive therapy in the treatment of partial onset seizures, with and without secondary generalization, in adults and pediatric patients over 3 years of age.
• Diabetic Peripheral Neuropathy (DPN): Off-label global gold-standard management of burning, tingling, and numbness in the extremities associated with chronic diabetes.
• Restless Legs Syndrome (RLS): Management of moderate-to-severe primary RLS in adults.

Dosage & Administration

Recommended Dosage (Strictly as per Neurologist/Physician):

• Administration: Taken orally, with or without food. Doses should not exceed 12 hours between administrations to prevent breakthrough seizures.
• Standard Titration: Dosing must begin low (e.g., 300 mg once on Day 1, twice on Day 2, three times on Day 3) to minimize dizziness and somnolence. Maintenance doses typically range from 900 mg to 3600 mg per day, divided into three doses.
• Discontinuation Protocol (CRITICAL): Gabapentin must NEVER be stopped abruptly. Sudden discontinuation can cause severe withdrawal symptoms, anxiety, insomnia, and trigger status epilepticus (continuous, life-threatening seizures). The dose must be tapered gradually over a minimum of 1 week.

Safety Warnings (CRITICAL):

• CNS Depression & Dizziness: Gabapentin frequently causes significant somnolence (sleepiness), dizziness, and ataxia (loss of coordination), heavily increasing the risk of accidental falls in the elderly. Co-administration with opioids, alcohol, or benzodiazepines can lead to fatal respiratory depression.
• Suicidal Behavior/Ideation: Like all antiepileptic drugs, Gabapentin carries an increased risk of suicidal thoughts or behavior. Patients should be strictly monitored for the emergence or worsening of clinical depression.
• Antacid Interaction: Co-administration with aluminum or magnesium-based antacids drastically reduces the bioavailability of Gabapentin by up to 20%. It must be taken at least 2 hours after taking an antacid.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Neurological Formulations, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government neuropathy programs in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.