Description
Clotrimazole Vaginal Tablets (Pessaries)
Healthy Inc is a specialized global supplier and exporter of gynecological anti-infectives. We provide high-purity Clotrimazole Vaginal Tablets (often supplied with applicators), sourced from WHO–GMP certified solid dosage facilities. This “Local Antifungal” is a top export to women’s health clinics, maternity hospitals, and pharmacy chains in Africa, LATAM, and Southeast Asia, serving as the first-line treatment for Vulvovaginal Candidiasis (Vaginal Thrush/Yeast Infection).
Product Overview
This formulation contains Clotrimazole, a broad-spectrum imidazole antifungal designed for intravaginal use.
The “Intimate Care” Specialist:
- Mechanism: Clotrimazole inhibits the enzyme 14-alpha-demethylase, which is vital for synthesizing ergosterol (a key component of the fungal cell membrane). Without ergosterol, the membrane becomes leaky, causing the fungus to lose essential nutrients and die.
- High Local Concentration: Unlike oral antifungals (like Fluconazole), vaginal tablets deliver a high concentration of the drug directly to the site of infection with minimal systemic absorption (3-10%). This reduces the risk of systemic side effects.
- Formulation Science: These tablets are engineered to disintegration in small amounts of vaginal fluid. They are often lactose-based to encourage the growth of healthy lactobacilli while treating the infection.
Product Composition & Strength
We supply this product as Uncoated Vaginal Tablets (bullet or almond shaped) with or without an applicator, offering flexible treatment durations.
| Active Ingredient | Strength | Treatment Course | Patient Convenience |
|---|---|---|---|
| Clotrimazole USP/BP | 100 mg | 6 Nights | Standard Therapy |
| Clotrimazole USP/BP | 200 mg | 3 Nights | Short Course |
| Clotrimazole USP/BP | 500 mg | 1 Night | Single Dose (“One Shot”) |
| Excipients | Q.S. | Lactose / Adipic Acid / Starch | Rapid Disintegration |
*Pack Sizes: Blister packs of 1s (500mg), 3s (200mg), or 6s (100mg), boxed with a plastic applicator.
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.20.19 (Medicaments containing antibiotics/antifungals) |
| Dosage Form | Vaginal Tablet (Pessary) |
| Packaging | PVC-Alu Blister or Alu-Alu Strip |
| Storage | Store below 25°C. Avoid heat (melts/deforms). |
| Certificates | WHO-GMP, COPP, Free Sale Certificate |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Mucoadhesion: The tablet matrix includes specific binders that allow the medication to adhere to the vaginal mucosa after disintegration, ensuring prolonged contact time with the infected tissue.
- pH Balance: The formulation typically includes mild acidifiers (like Adipic or Lactic acid) to help restore the natural acidic pH of the vagina, creating an environment hostile to Candida yeast.
Therapeutic Indications (Human Use)
Indicated for the local treatment of fungal infections:
- Vulvovaginal Candidiasis (VVC): Also known as vaginal thrush or yeast infection.
- Mixed Infections: Effective against vaginal superinfections caused by susceptible gram-positive bacteria.
- Sanitization: Sometimes used pre-delivery to sanitize the birth canal (under medical supervision).
Dosage & Administration
Recommended Dosage (Strictly as per Gynecologist):
- Route: Intravaginal only. Do not swallow.
- 100 mg: Insert one tablet deep into the vagina for 6 consecutive nights.
- 200 mg: Insert one tablet deep into the vagina for 3 consecutive nights.
- 500 mg: Insert one tablet deep into the vagina as a single dose.
- Timing: Best inserted at bedtime to prevent the tablet from falling out due to gravity.
- Applicator: Use the provided applicator for deep insertion. Pregnant women should insert by finger to avoid cervical trauma.
Safety Warnings:
- Pregnancy: Generally considered safe in the 2nd and 3rd trimesters, but caution is advised regarding the use of applicators. Consult a doctor.
- Menstruation: Treatment should not be performed during menstruation as the blood flow washes the drug away.
- Contraceptives: Some vaginal formulations may damage latex condoms and diaphragms, reducing their effectiveness. Abstinence is recommended during treatment.
- Partner Treatment: Sexual partners should only be treated if they have symptoms.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.
