Azilsartan Medoxomil Tablets

Description

Azilsartan Medoxomil Film-Coated Tablets (40 mg / 80 mg)

Healthy Inc is a specialized global supplier and exporter of advanced cardiology, nephrology, and targeted cardiovascular therapeutics. We provide ultra-high-purity, kinetically optimized Azilsartan Medoxomil Tablets, manufactured in WHO–GMP certified, high-precision oral solid dosage facilities. This “Next-Generation ARB” is a premium strategic export to cardiology hospitals, hypertension centers, and government health ministries, serving as the globally mandated intervention for Essential Hypertension and 24-hour ambulatory blood pressure management.

Product Overview

This formulation operates as a high-affinity “Vessel Relaxant.” Azilsartan is a prodrug (Medoxomil ester) that is rapidly converted to its active form, providing a more potent and sustained blockade of the receptors that cause blood vessels to tighten.

• Mechanism 1 (Selective AT1 Blockade): Azilsartan selectively binds to the Angiotensin II Type 1 ($AT_1$) Receptors with much higher affinity and slower dissociation than older ARBs. By blocking these receptors, it prevents Angiotensin II from causing vasoconstriction (tightening of the vessels).

   

• Mechanism 2 (Sustained 24-Hour Control): Due to its unique chemical binding, Azilsartan provides superior 24-hour blood pressure reduction, particularly during the early morning hours when the risk of stroke and heart attack is highest.

• Mechanism 3 (Aldosterone Suppression): By blocking the $AT_1$ receptor, it also reduces the secretion of Aldosterone, leading to decreased sodium and water retention by the kidneys, further lowering blood pressure.

Product Composition & Strength

We supply this product as a Precision-Blended, High-Bioavailability Tablet, packed in moisture-resistant Alu-Alu blister strips to ensure the stability of the Medoxomil ester.

Technical & Logistics Specifications

• HS Code: 3004.90.99 (Medicaments containing other active substances – Cardiovascular)

   

• CAS Number: 863031-21-4 (Azilsartan Medoxomil Potassium)

• Dosage Form: Film-Coated Tablet

   

• Packaging: Alu-Alu Blisters (MANDATORY). Azilsartan Medoxomil is highly sensitive to moisture; our moisture-lock packaging ensures 24-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Medoxomil Stability Mastery: Our manufacturing process focuses on absolute environmental control, ensuring the Medoxomil ester remains intact and free from degradation, providing 100% bioequivalence to the innovator brand (Edarbi).

• Impurity Profiling: We utilize advanced HPLC to monitor for nitrosamine-free synthesis, meeting the latest global safety standards for ARB class medications.

Primary Indications

• Cardiology: Treatment of Essential Hypertension (High Blood Pressure) in adults.

   

• Nephrology: Management of hypertension in patients with early-stage chronic kidney disease (under specialist supervision).

Dosage & Administration

• Standard Adult Dosing: 40 mg once daily, with or without food. The dose may be increased to 80 mg if blood pressure is not adequately controlled.

   

• The “Morning Pulse” Advantage: Taking the tablet in the morning ensures maximum protection during the peak physiological blood pressure surge.

Safety Warning: Fetal Toxicity. Strictly contraindicated in pregnancy. Monitor for Hyperkalemia (high potassium) and renal function, especially in patients taking diuretics or those with kidney impairment.

 

Global Export & Contract Manufacturing

Healthy Inc is a premier Cardiovascular Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for next-generation ARBs. Whether you are a Cardiology Specialist Network in Africa or a B2B Pharma Marketplace partner in Southeast Asia, we ensure secure, WHO-GMP compliant delivery.