ATENOLOL & INDAPAMIDE TABLETS

Description

Atenolol & Indapamide Tablets (50 mg / 2.5 mg)

Healthy Inc is a specialized global supplier and exporter of advanced cardiology, internal medicine, and targeted cardiovascular therapeutics. We provide ultra-high-purity, kinetically balanced Atenolol & Indapamide FDC Tablets, manufactured in WHO–GMP certified, high-precision oral solid dosage facilities. This “Cardio-Selective Beta Blocker & Metabolic-Neutral Diuretic FDC” is a massive-volume strategic export to hypertension clinics, geriatric hospitals, and government health ministries, serving as the globally mandated intervention for Essential Hypertension and Edema associated with Heart Failure.

Product Overview

This formulation operates as a “Dual-Pathway Fluid and Pressure Regulator.” It targets the volume-overload component of hypertension (Indapamide) while simultaneously “calming” the overactive cardiac output (Atenolol).

• Mechanism 1 (The Vascular Diuretic – Indapamide): Unlike standard Thiazides, Indapamide acts as both a diuretic and a direct vasodilator. It inhibits sodium reabsorption in the Distal Convoluted Tubule and has a specific calcium-channel-blocking effect on the blood vessel walls, leading to reduced peripheral resistance.

• Mechanism 2 (The Cardiac Governor – Atenolol): As a Beta-1 Selective Adrenoceptor Antagonist, Atenolol reduces the heart rate and the force of contraction. This lowers the heart’s oxygen demand and “blunts” the body’s stressful fight-or-flight response, providing 24-hour protection.

• Mechanism 3 (The Metabolic Advantage): Indapamide is “metabolically neutral,” meaning it does not significantly alter blood glucose or lipid levels. This makes the Atenolol/Indapamide combination a safer long-term choice for hypertensive patients who also have Type 2 Diabetes or Dyslipidemia.

Product Composition & Strength

We supply this product as a Precision-Blended, Film-Coated Tablet, engineered for synchronized 24-hour hemodynamic control.

Technical & Logistics Specifications

• HS Code: 3004.90.69 (Medicaments containing other active substances – Cardiovascular)

• CAS Numbers: 29122-68-7 (Atenolol) / 26807-65-8 (Indapamide)

• Dosage Form: Film-Coated Tablet

• Packaging: Alu-Alu or Alu-PVC Blisters. Requires protection from light and environmental humidity; our moisture-lock packaging ensures 24-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Diuretic Precision: Our facility utilizes High-Shear Granulation to ensure the specific 1:20 ratio of Indapamide to Atenolol is maintained with 100% content uniformity, preventing sub-therapeutic dosing.

• Nitrosamine-Free Synthesis: We utilize high-purity APIs that meet the latest global safety standards, ensuring maximum safety for the millions of patients requiring long-term hypertensive therapy.

Primary Indications

• Cardiology: Management of moderate to severe Essential Hypertension.

• Geriatrics: Preferred hypertensive therapy for elderly patients requiring a gentle diuretic.

• CHF Management: Treatment of edema associated with Congestive Heart Failure.

Dosage & Administration

• Standard Adult Dosing: 1 tablet once daily, preferably in the morning to maximize daytime blood pressure control.

• Administration: Must be swallowed whole with water.

Safety Warning: The Beta-Blocker Warning. Do not stop this medication abruptly. Sudden withdrawal can lead to rebound hypertension or heart palpitations. Monitor serum electrolytes (Potassium) periodically. Use with caution in patients with asthma or severe bradycardia.

Global Export & Contract Manufacturing

Healthy Inc is a premier Cardiovascular Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for essential Hypertension FDCs. Whether you are a Public Health Tender Buyer in Africa or a B2B Pharma Marketplace partner in the CIS, we ensure secure, WHO-GMP compliant delivery.