Aripipralzole Tablets

Description

Aripiprazole Tablets (5 mg / 10 mg / 15 mg / 20 mg / 30 mg)

Healthy Inc is a specialized global supplier and exporter of advanced CNS, psychiatry, and targeted neurological therapeutics. We provide ultra-high-purity, kinetically optimized Aripiprazole Tablets, manufactured in WHO–GMP certified, high-precision specialized CNS facilities. This “Third-Generation Atypical Antipsychotic” is a massive-volume strategic export to mental health hospitals, neurology clinics, and government health ministries, serving as the globally mandated intervention for Schizophrenia, Bipolar I Disorder, and as adjunctive therapy for Major Depressive Disorder (MDD).

Product Overview

This formulation operates as a biochemical “Thermostat.” Aripiprazole is unique because it doesn’t just “turn off” brain signals; it stabilizes them to maintain a healthy baseline of neurotransmitter activity.

• Mechanism 1 (D2 Partial Agonism): Aripiprazole binds to Dopamine $D_2$ Receptors. In areas of the brain with high dopamine (causing hallucinations), it acts as an antagonist to lower activity. In areas with low dopamine (causing lack of motivation), it acts as an agonist to stimulate activity.

   

• Mechanism 2 (Serotonin 5-$HT_{1A}$ & 5-$HT_{2A}$ Modulation): It acts as a partial agonist at 5-$HT_{1A}$ and an antagonist at 5-$HT_{2A}$ receptors. This dual action helps improve mood, reduce anxiety, and minimize the physical “shaking” side effects common with older medications.

• Mechanism 3 (The “Clean” Metabolic Profile): Aripiprazole has minimal affinity for Histamine ($H_1$) and Muscarinic receptors. This translates to less sedation, less dry mouth, and a significantly lower risk of weight gain and diabetes compared to other atypical antipsychotics.

Product Composition & Strength

We supply this product in a wide range of strengths to allow for precise clinical titration, packed in moisture-resistant Alu-Alu blister strips.

Technical & Logistics Specifications

• HS Code: 3004.90.79 (Other medicaments acting on the CNS – Antipsychotics)

• CAS Number: 129722-12-9 (Aripiprazole)

   

• Dosage Form: Uncoated or Film-Coated Tablet (Scored for flexibility)

• Packaging: Alu-Alu Blisters (MANDATORY). Aripiprazole is sensitive to environmental moisture; our moisture-lock packaging ensures 24-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Receptor Affinity Precision: Our manufacturing process focuses on absolute chemical purity to ensure the D2/5-HT receptor binding ratio remains exact, providing the predictable clinical stabilization required for psychiatric patients.

• Content Uniformity Mastery: We utilize High-Shear Granulation to ensure that even the 2 mg and 5 mg micro-doses are distributed with 100% uniformity across every tablet in a million-unit batch.

Primary Indications

• Psychiatry: Treatment of Schizophrenia in adults and adolescents (13-17 years).

• Mood Disorders: Acute treatment of manic or mixed episodes associated with Bipolar I Disorder.

   

• Depression: Adjunctive (add-on) treatment for Major Depressive Disorder when antidepressants alone are insufficient.

   

• Pediatrics: Management of irritability associated with Autistic Disorder (6-17 years).

   

Dosage & Administration

• Standard Dosing: Usually started at 10 mg or 15 mg once daily for Schizophrenia.

   

• Administration: Can be taken with or without food. Consistent timing is critical to maintain steady-state plasma levels.

Safety Warning: Elderly Warning. Increased risk of death in elderly patients with dementia-related psychosis. Monitor for Akathisia (restlessness) and suicidal thoughts, especially in young adults during the first few weeks of therapy.

 

Global Export & Contract Manufacturing

Healthy Inc is a premier CNS Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for next-generation Antipsychotics. Whether you are a Mental Health Hospital Network in Africa or a B2B Pharma Marketplace partner in the CIS, we ensure secure, WHO-GMP compliant delivery.