Description
Acetaminophen & Tramadol Hydrochloride Tablets (325 mg / 37.5 mg)
Healthy Inc is a specialized global supplier and exporter of advanced analgesics, orthopedic, and targeted internal medicine therapeutics. We provide ultra-high-purity, kinetically balanced Acetaminophen & Tramadol FDC Tablets, manufactured in WHO–GMP certified, high-precision specialized oral solid dosage facilities. This “Non-Opioid & Opioid Analgesic FDC” is a massive-volume strategic export to surgical hospitals, pain management clinics, and government health ministries, serving as a globally preferred intervention for moderate-to-severe acute pain.
Product Overview
This formulation operates as a “Dual-Phase Pain Interceptor.” It is engineered to attack pain from two different directions, providing faster relief and longer duration than either drug used alone.
Mechanism 1 (The Peripheral Response – Acetaminophen): Acetaminophen (Paracetamol) works primarily in the central nervous system by inhibiting Cyclooxygenase (COX) enzymes and potentially interacting with the endocannabinoid system. It raises the patient’s overall pain threshold and rapidly reduces fever.
Mechanism 2 (The Central Mu-Opioid Agonist – Tramadol): Tramadol binds to the $\mu$-opioid receptors in the brain and spinal cord, physically “muffling” the transmission of pain signals from the site of injury to the mind.
Mechanism 3 (The Monoamine Reuptake Inhibition): Unique among opioids, Tramadol also inhibits the reuptake of Norepinephrine and Serotonin. This enhances the body’s natural “descending inhibitory pathways,” providing a secondary layer of pain control often missing in traditional narcotics.
Product Composition & Strength
We supply this product in the globally standardized “325/37.5” ratio, optimized for maximum efficacy with minimal opioid-related side effects.
| Active Ingredient | Strength | Primary Clinical Function |
| Acetaminophen (Paracetamol) USP/BP | 325 mg | The Rapid Starter: Provides quick onset of analgesia and antipyretic (fever-reducing) effects. |
| Tramadol Hydrochloride USP/BP | 37.5 mg | The Sustained Blocker: Provides moderate-to-severe pain relief via opioid and neurotransmitter pathways. |
| Excipients | Proprietary Matrix | Bio-Synchronized System: Engineered to ensure both APIs reach therapeutic plasma levels simultaneously for a synergistic effect. |
Technical & Logistics Specifications
HS Code: 3004.90.99 (Medicaments acting on the CNS – Analgesics)
CAS Numbers: 103-90-2 (Acetaminophen) / 27203-92-5 (Tramadol HCl)
Dosage Form: Film-Coated Tablet
Packaging: Alu-Alu or Alu-PVC Blisters. Protects the API from environmental humidity; our moisture-lock packaging ensures 24-month stability in Zone IVb tropical climates.
Manufacturing Authority & Compliance
Controlled Substance Precision: Tramadol is a regulated molecule in many jurisdictions. Our facility utilizes Advanced Inventory & Security Protocols for controlled substance handling, ensuring 100% legal compliance for international exports.
Impurity Profiling: Our manufacturing process focuses on absolute chemical purity, specifically monitoring for 4-aminophenol (in Acetaminophen) and related substances in Tramadol to ensure the highest safety profile.
Primary Indications
Orthopedics: Management of moderate-to-severe pain associated with osteoarthritis or rheumatoid arthritis.
Post-Operative Care: Short-term (five days or less) management of acute pain following surgical procedures.
Pain Management: Treatment of severe dental pain, lower back pain, and musculoskeletal injuries.
Dosage & Administration
Standard Adult Dosing: 2 tablets every 4 to 6 hours as needed for pain relief, up to a maximum of 8 tablets per day.
Administration: Can be taken with or without food.
Safety Warning: Liver Toxicity. Contains Acetaminophen; do not exceed 4000 mg of Acetaminophen per day from all sources to avoid severe liver damage. CNS Depression: May cause drowsiness; avoid alcohol and other CNS depressants. Seizure Risk: Use with caution in patients with a history of epilepsy or those taking antidepressants (SSRIs/SNRIs).
Global Export & Contract Manufacturing
Healthy Inc is a premier Analgesic Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-precision Pain Management FDCs. Whether you are a Trauma Center Supply Chain in Africa or a B2B Pharma Marketplace partner in the CIS, we ensure secure, WHO-GMP compliant delivery.
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