Tobramycin Ophthalmic Solution

Description

Tobramycin Ophthalmic Solution (0.3% w/v)

Healthy Inc is a specialized global supplier and exporter of advanced anti-infectives, ophthalmology, and targeted antimicrobial therapeutics. We provide ultra-high-purity, kinetically stabilized Tobramycin Eye Drops, manufactured in WHO–GMP certified, high-precision sterile ophthalmic facilities. This “Potent Aminoglycoside” is a massive-volume strategic export to retail pharmacies, eye hospitals, and government health ministries, serving as the globally preferred intervention for the treatment of external infections of the eye and its adnexa caused by susceptible bacteria.

Product Overview

This formulation operates as a “Ribosomal Protein Interrupter.” It physically enters the bacterial cell to shut down its life-support systems, providing rapid bactericidal action against a wide spectrum of ocular pathogens.

• Mechanism 1 (30S Ribosomal Binding): Tobramycin physically binds to the 30S subunit of the bacterial ribosome. This causes a misreading of the genetic code (mRNA).

• Mechanism 2 (Protein Synthesis Halt): By disrupting the reading of the genetic code, it physically prevents the bacteria from producing the essential proteins required for growth and replication.

• Mechanism 3 (Cell Membrane Disruption): At high concentrations, it physically destabilizes the bacterial cell wall, leading to rapid cell death (Bactericidal action).

Product Composition & Strength

We supply this product in a Sterile, Buffered, Isotonic Aqueous Solution, optimized for high ocular tolerance and stability.

Technical & Logistics Specifications

• HS Code: 3004.20.19 (Medicaments containing other antibiotics – Ophthalmic)

• CAS Number: 32986-56-4 (Tobramycin)

• Dosage Form: Sterile Eye Drops (Ophthalmic Solution)

• Packaging: Sterile LDPE Dropper Bottles (5ml). Our specialized ophthalmic packaging ensures 24-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Aseptic Filling Excellence: Our manufacturing process utilizes Class 100 (ISO 5) Sterile Filling Lines. This ensures the solution is 100% free from microbial contaminants, a non-negotiable requirement for infected eyes.

• High-Purity Fractionation: We utilize Advanced Purification Techniques to ensure our Tobramycin is free from related substances, maximizing its “Gentle-on-the-Cornea” profile compared to generic Gentamicin.

Primary Indications

• Ophthalmology: Treatment of Bacterial Conjunctivitis, Keratitis, and Blepharitis caused by Staphylococci, Streptococci, and Pseudomonas aeruginosa.

• Pediatrics: Preferred antibiotic for childhood “Pink Eye” due to its high safety profile and low stinging sensation.

• Surgery: Used as a prophylactic agent to prevent infection following foreign body removal or minor ocular trauma.

Dosage & Administration

• For Mild to Moderate Infection: Typically 1 or 2 drops in the affected eye(s) every 4 hours.

• For Severe Infection: 2 drops in the affected eye(s) every hour until improvement is noted, then reduce frequency.

• Administration: Apply to the conjunctival sac. To minimize systemic absorption, the patient should apply pressure to the tear duct for 1 minute after instillation.

Safety Warning: For Ophthalmic Use Only. Vision Warning: May cause temporary blurred vision; do not drive until vision is clear. Resistance Warning: To prevent the development of resistant bacteria, the medication should be used for the full prescribed duration. Contraindication: Do not use if known hypersensitivity to Tobramycin or other aminoglycosides exists.

Global Export & Contract Manufacturing

Healthy Inc is a premier Ophthalmic and Anti-Infective Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume sterile antibiotic eye drops. Whether you are a National Health Tender in Africa or a B2B Pharma Marketplace partner in the CIS, Middle East, or LATAM, we ensure secure, WHO-GMP compliant delivery.