Healthy Inc > Blog > WHO-GMP pharma exporter
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What is Cimetidine 400mg used for?

In the pharmaceutical industry, Cimetidine 400 mg is the pioneer H2-receptor antagonist (H2RA) used to suppress gastric acid secretion. While newer proton pump inhibitors (PPIs) have gained popularity, Cimetidine remains a vital, cost-effective therapeutic option for managing acid-peptic disorders, especially in international markets where affordability is a priority.

Primary Clinical Uses

  • Duodenal and Gastric Ulcers: Indicated for the short-term treatment of active ulcers and as maintenance therapy to prevent recurrence.

  • Gastroesophageal Reflux Disease (GERD): Relieves symptoms like heartburn and acid regurgitation caused by the backflow of stomach acid into the esophagus.

  • Zollinger-Ellison Syndrome: Manages pathological hypersecretory conditions where the stomach produces excessive amounts of acid.

  • Prophylaxis of GI Bleeding: Used in critical care settings to prevent stress-induced ulcers and upper gastrointestinal bleeding.

  • Off-label Dermatological Use: Occasionally used in high doses for the treatment of viral warts (verrucae) due to its immunomodulatory properties.

    Mechanism of Action

Cimetidine works by competitively inhibiting histamine at the H2-receptors located on the basolateral membrane of the gastric parietal cells.

By blocking these receptors, it inhibits both the basal (fasting) and stimulated (food-induced) secretion of gastric acid. This results in a significant reduction in the volume of gastric juice and its hydrogen ion concentration, allowing the mucosal lining to heal.

The Manufacturer’s Perspective: Formulation & Export

From a manufacturing and global trade standpoint, Cimetidine 400 mg is a high-volume, “essential medicine” staple:

  • Drug-Drug Interactions (CYP450): As a pharmacist, you know Cimetidine is a potent inhibitor of several cytochrome P450 enzymes (e.g., 1A2, 2C9, 2D6). In our professional labeling and dossiers, we emphasize these interactions to ensure patient safety when co-administered with drugs like Warfarin or Theophylline.

  • Stability for Global Markets: Cimetidine is a stable molecule, but as a WHO-GMP manufacturer, we utilize PVC/PVDC or Alu-Alu blister packaging to ensure its 36-month shelf life remains intact during export to Zone IVb climates (Africa, SE Asia, and Latin America).

  • B2B & Public Health Tenders: Because Cimetidine is often more affordable than modern PPIs, it remains a high-demand item for government health tenders and low-cost B2B distribution networks.

  • Regulatory Readiness: Our Mumbai-based facility provides comprehensive CTD/eCTD Dossiers and stability data (BP/USP/IP) to facilitate rapid registration for our international partners.

Cimetidine Tablets

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What is Cilostazol 50 mg used for?

In the pharmaceutical industry, Cilostazol 50 mg is a specific phosphodiesterase III (PDE3) inhibitor with potent antiplatelet and vasodilatory properties. As a pharmacist, I view Cilostazol as a unique therapeutic agent because, unlike standard antiplatelets like Aspirin, it actively improves blood flow by dilating the arteries while simultaneously preventing clot formation.

Primary Clinical Uses

  • Intermittent Claudication: The primary indication for Cilostazol is the reduction of symptoms of intermittent claudication (leg pain, cramping, or tiredness while walking) in patients with Peripheral Arterial Disease (PAD). It increases the distance patients can walk without pain.

  • Secondary Stroke Prevention: In some regions, it is used as an alternative or adjunct for the prevention of ischemic stroke, particularly in patients who cannot tolerate other antiplatelet therapies.

  • Percutaneous Coronary Intervention (PCI): Occasionally used off-label to prevent restenosis after stent placement.

  • Buerger’s Disease (Thromboangiitis Obliterans): Used to improve circulation in the small and medium-sized arteries of the hands and feet.

Mechanism of Action

Cilostazol works through a dual-action biochemical pathway:

Inhibition of PDE3: By inhibiting the phosphodiesterase III enzyme, Cilostazol increases the levels of cyclic adenosine monophosphate (cAMP) within platelets and blood vessel walls.

Antiplatelet Effect: Higher cAMP levels in platelets prevent them from aggregating (clumping), which reduces the risk of thrombus formation.

Vasodilation: Increased cAMP in the vascular smooth muscle cells leads to relaxation of the arteries (vasodilation), which directly increases blood flow to the limbs.

The Manufacturer’s Perspective: Formulation & Export

From a manufacturing and global trade standpoint, Cilostazol 50 mg is a specialized cardiovascular product:

  • Bioavailability Challenges: Cilostazol is practically insoluble in water. As a WHO-GMP manufacturer, we utilize micronization technology to reduce particle size, ensuring consistent dissolution and optimal absorption.

  • Dose Titration: We manufacture both 50 mg and 100 mg strengths. The 50 mg tablet is essential for patients who require a lower dose due to side effects like headaches or for those taking co-medications (like CYP3A4 inhibitors) that increase Cilostazol levels.

  • Stability for Export: We utilize Alu-Alu blister packaging to protect the tablets from moisture and light, ensuring a 24-month shelf life for export to Zone IVb regions (Africa, SE Asia, and the Middle East).

  • Regulatory Support: Our Mumbai-based facility provides comprehensive CTD/eCTD Dossiers and comparative dissolution data against the innovator (Pletal) to support international registration and B2B trade.

Cilostazol Tablets

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What is Trypsin Chymotrypsin Tablet 100000 used for?

In the pharmaceutical industry, Trypsin-Chymotrypsin tablets (standardized at 100,000 Armour Units) are a potent proteolytic enzyme combination. As a pharmacist, I view this formulation as a highly effective “biological response modifier” used to accelerate the resolution of inflammatory edema and promote tissue repair following trauma or surgery.

Primary Clinical Uses

  • Post-Operative Inflammation: Extensively used after surgical procedures (orthopedic, gynecological, or general surgery) to reduce swelling, hematoma (bruising), and pain at the incision site.

  • Traumatic Injuries: Indicated for the management of accidental injuries, such as sprains, strains, fractures, and sports-related soft tissue trauma.

  • Chronic Respiratory Conditions: Used as an adjunctive therapy in conditions like bronchitis and sinusitis to thin out thick mucus secretions (mucolytic effect), making them easier to expectorate.

  • Pelvic Inflammatory Disease (PID): Often prescribed in gynecology to resolve inflammation and improve the penetration of antibiotics into the affected tissues.

  • Tooth Extractions: Frequently used in dentistry to minimize post-extraction swelling and pain.

Mechanism of Action

Trypsin and Chymotrypsin are enzymes that act as anti-inflammatory catalysts. Unlike NSAIDs (which inhibit COX enzymes), these proteolytic enzymes work through the following pathways:

Fibrinolysis: They break down fibrin deposits that form around inflamed areas. These fibrin walls often “wall off” the infection, trapping fluid and preventing antibiotics from reaching the site.

Restoring Microcirculation: By clearing fibrin and cellular debris, these enzymes restore the flow of blood and lymph in the micro-vasculature. This reduces edema (swelling) and allows the body’s natural defense mechanisms to clear the inflammation.

TNF-$\alpha$ Modulation: They help regulate pro-inflammatory cytokines, preventing an excessive or prolonged inflammatory response.

The Manufacturer’s Perspective: Formulation & Export

From a manufacturing and global trade standpoint, Trypsin-Chymotrypsin is a technically sensitive biological product:

  • Enteric Coating (Crucial): These enzymes are proteins that would be instantly destroyed by stomach acid. As a WHO-GMP manufacturer, we utilize a high-quality enteric coating that ensures the tablet remains intact in the stomach and only dissolves in the $pH$-neutral environment of the small intestine.

  • Potency & Standardization: We measure efficacy in Armour Units (or AU). Ensuring that each tablet provides exactly 100,000 units requires precise API handling and environmental controls to prevent enzymatic degradation during the manufacturing process.

  • Stability for Export: Enzymes are heat-sensitive. We prioritize Alu-Alu blister packaging to protect the tablets from moisture and temperature fluctuations during transit to Zone IVb regions.

  • B2B & Surgical Supply: This is a high-demand item for surgical hospitals and orthopedic clinics. Our Mumbai facility provides the CTD/eCTD Dossiers and stability data required for international registration and hospital tenders.

Chymotrypsin Tablets

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What is Cholecalciferol 60000 IU granules used for?

In the pharmaceutical industry, Cholecalciferol (Vitamin D3) 60,000 IU granules represent a high-potency “mega-dose” formulation. As a pharmacist, I characterize this product as a therapeutic loading dose rather than a daily supplement. It is specifically designed to rapidly correct clinical vitamin D deficiency and replenish depleted hepatic and adipose stores.

Primary Clinical Uses

  • Treatment of Vitamin D Deficiency: Specifically for patients with serum 25-hydroxyvitamin D [25(OH)D] levels significantly below 20 ng/mL.

  • Osteoporosis Management: Used as an intensive adjunct to primary osteoporosis therapies (like Bisphosphonates) to ensure adequate calcium absorption and bone mineralization.

  • Osteomalacia & Rickets: Essential for reversing the softening of bones in adults (osteomalacia) and correcting skeletal deformities in children (rickets).

  • Malabsorption Syndromes: Frequently prescribed for patients with conditions like Celiac disease, Crohn’s disease, or post-bariatric surgery, where standard daily doses are insufficient due to poor intestinal absorption.

  • Hypoparathyroidism: Used to maintain calcium homeostasis when parathyroid hormone function is compromised.

Mechanism of Action

Cholecalciferol is a fat-soluble vitamin that acts more like a pro-hormone. Once ingested:

  1. Hydroboxylation: It undergoes two hydroxylation steps—first in the liver to form 25(OH)D (Calcifediol) and then in the kidneys to form 1,25$(OH)_2$D (Calcitriol), the biologically active form.

  2. Target Action: Calcitriol binds to Vitamin D Receptors (VDR) in the intestines to stimulate the synthesis of calbindin, a protein that actively transports calcium across the intestinal mucosa into the bloodstream.

The Manufacturer’s Perspective: Formulation & Export

From a manufacturing and global trade standpoint, 60,000 IU granules are a high-value niche product:

  • Granulation Technology: As a WHO-GMP manufacturer, we utilize fluid-bed processing to create free-flowing granules. The Vitamin D3 is often “beadletted” or micro-encapsulated to protect it from oxidation and light, which are the primary causes of degradation.

  • Sachet Packaging: Granules are typically packed in 1g or 2g triple-laminated sachets (Polyester/Alu/Poly) to provide a complete barrier against moisture and oxygen, ensuring a stable 24-month shelf life even in Zone IVb climates.

  • Dosing Schedule: Unlike daily tablets, these granules are usually administered once weekly or once monthly, which significantly improves patient compliance for chronic bone-health management.

  • Global Export Profile: Operating from Mumbai, we provide the CTD/eCTD Dossiers and stability data required for international registration. This high-strength formulation is a staple for B2B distributors in regions with limited sunlight or high rates of nutritional deficiency.

Cholecalciferol Granules Sachet

 

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What is Chlorpromazine 25mg used for?

In the pharmaceutical industry, Chlorpromazine Hydrochloride 25 mg is the prototypical first-generation (typical) antipsychotic of the phenothiazine class. As a pharmacist, I characterize Chlorpromazine as a “low-potency” antipsychotic that is highly versatile due to its multi-receptor blocking profile, making it useful far beyond psychiatry.

Primary Clinical Uses

  • Psychotic Disorders: Management of schizophrenia and the manic phase of bipolar disorder, particularly for controlling agitation and aggressive behavior.

  • Severe Nausea and Vomiting: Used as a potent antiemetic, especially for intractable nausea caused by advanced illness or certain medications.

  • Intractable Hiccups: It is one of the few medications specifically indicated for the treatment of hiccups that have persisted for days or weeks.

  • Acute Intermittent Porphyria: Used as part of the clinical management of this rare metabolic disorder.

  • Pre-operative Sedation: Occasionally used to reduce anxiety and induce sedation before surgery.

Mechanism of Action

Chlorpromazine is a “dirty drug” in pharmacological terms—meaning it acts on a wide variety of receptors, which explains its diverse clinical effects:

Dopamine Antagonism: It blocks  receptors in the mesolimbic and medullary chemoreceptor trigger zone (CTZ). By inhibiting dopamine overactivity, it reduces “positive” symptoms of psychosis and provides antiemetic effects.

H1-Receptor Blockade: Its action on histamine receptors leads to significant sedation, useful for acute agitation.

Alpha-Adrenergic Blockade: This can lead to cardiovascular effects like orthostatic hypotension.

Muscarinic Blockade: Its anticholinergic effects can cause dry mouth and blurred vision.

The Manufacturer’s Perspective: Formulation & Export

From a manufacturing and global trade standpoint, Chlorpromazine 25 mg is a specialized CNS (Central Nervous System) product:

  • Photosensitivity Management: Chlorpromazine API is highly sensitive to light. As a WHO-GMP manufacturer, we utilize amber-colored glass bottles or opaque blister packaging to ensure chemical stability.

  • Dose Uniformity: Because 25 mg is a relatively low dose for this molecule, we utilize validated wet granulation and blending processes to ensure absolute content uniformity across every batch.

  • Global Export Stability: It remains a staple for psychiatric hospitals and government tenders in the CIS, Africa, and Southeast Asia. We provide the CTD/eCTD Dossiers and stability data required for international registration.

  • Regulatory Standards: We ensure all batches comply with BP/USP/IP monographs, specifically monitoring for degradation products like Chlorpromazine Sulfoxide.

Chlorpromazine Hydrochloride Tablets

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What is CPM Chlorpheniramine Maleate used for?

In the pharmaceutical industry, Chlorpheniramine Maleate (CPM), typically manufactured in 4 mg tablets or as a syrup (2 mg/5 ml), is a classic first-generation H1-receptor antagonist of the alkylamine class. As a pharmacist, I characterize CPM as a versatile, high-potency antihistamine that is particularly valued for its rapid onset and its role as a “gold standard” ingredient in multi-action cold and flu formulations.

Primary Clinical Uses

  • Allergic Rhinitis: Effective relief from seasonal and perennial allergies, including sneezing, runny nose, and itchy/watery eyes.

  • Urticaria and Angioedema: Used to manage skin allergies, hives, and localized swelling.

  • Common Cold Symptoms: Frequently combined with decongestants and antipyretics (like Paracetamol) to reduce nasal secretions and “drying up” a runny nose.

  • Allergic Conjunctivitis: Relief of ocular itching and redness.

  • Anaphylactic Reactions: Used as adjunctive therapy (after Epinephrine) to control secondary allergic symptoms.

Mechanism of Action

CPM works by competitively blocking the H1-receptor sites on effector cells. By preventing histamine from binding to these receptors, it inhibits:

  1. Vascular permeability: Reducing swelling and fluid leakage.

  2. Smooth muscle contraction: Relieving respiratory and gastrointestinal constriction.

  3. Sensory nerve stimulation: Eliminating the “itch” sensation.

Unlike second-generation antihistamines (like Cetirizine), CPM readily crosses the Blood-Brain Barrier, which accounts for its significant sedative effect. This “side effect” is often utilized clinically to help patients sleep when allergy symptoms are severe.

The Manufacturer’s Perspective: Formulation & Export

From a manufacturing and global trade standpoint, CPM is a core essential for any pharmaceutical portfolio:

  • API Versatility: CPM is a highly stable salt. As a WHO-GMP manufacturer, we utilize it in various dosage forms, from standalone 4 mg tablets to complex multi-ingredient “Cold & Flu” syrups and tablets.

  • Dose Precision: Because CPM is potent at low doses, we ensure absolute content uniformity through validated micro-blending techniques during the granulation process.

  • Global Export Stability: CPM is remarkably robust. We utilize PVC/PVDC or Alu-Alu blister packaging to guarantee a 36-month shelf life, even in the most challenging Zone IVb (hot and humid) environments across Africa and Southeast Asia.

  • B2B & Tender Supply: CPM is a high-volume “Essential Medicine.” Our Mumbai-based facility provides full CTD/eCTD Dossier support, making it a staple for government tenders and international B2B distributors.

Chlorpheniramine Tablets

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What is Chloroquine Phosphate 250mg used for?

In the pharmaceutical industry, Chloroquine Phosphate 250 mg (equivalent to 150 mg of Chloroquine base) is a 4-aminoquinoline derivative that has served as a foundational antimalarial and amebicidal agent for decades. As a pharmacist, I characterize Chloroquine as a high-volume essential medicine that remains a first-line choice in regions where parasite sensitivity is still maintained.

Primary Clinical Uses

  • Prophylaxis and Treatment of Malaria: Indicated for the prevention and treatment of acute attacks of malaria caused by Plasmodium vivax, P. malariae, P. ovale, and susceptible strains of P. falciparum.

  • Extra-intestinal Amebiasis: Specifically used to treat amebic liver abscesses caused by Entamoeba histolytica when other treatments are not suitable.

  • Autoimmune Disorders: Frequently used off-label or as a secondary therapy for Rheumatoid Arthritis and Systemic Lupus Erythematosus (SLE) due to its mild immunosuppressive and anti-inflammatory properties.

Mechanism of Action

Chloroquine acts as a blood schizontocide. It enters the malaria parasite’s acidic food vacuole and inhibits the enzyme heme polymerase.

Normally, the parasite digests host hemoglobin and releases toxic free heme, which it then detoxifies into non-toxic hemozoin (malaria pigment). Chloroquine prevents this detoxification; the resulting accumulation of free heme is highly toxic, leading to the rapid lysis and death of the parasite.

The Manufacturer’s Perspective: Formulation & Export

From a manufacturing and global trade standpoint, Chloroquine Phosphate is a staple of high-capacity production:

  • API Purity & Standardization: As a WHO-GMP manufacturer, we ensure the API meets BP/USP/IP monographs, specifically monitoring for related substances and heavy metals to ensure long-term safety in chronic users.

  • Stability for Global Trade: Chloroquine is a robust molecule. We utilize PVC/PVDC or Alu-Alu blister packaging to ensure a stable 36-month shelf life, facilitating bulk exports to Zone IVb climates (Africa, SE Asia).

  • Volume and Tender Supply: Due to its cost-effective profile, Chloroquine 250 mg is a high-volume item for government health tenders and B2B distributors. Our Mumbai-based facility is optimized for the scale required for these large-scale international contracts.

  • Dossier Support: We provide comprehensive CTD/eCTD Dossiers to assist international partners in the registration process, ensuring compliance with global regulatory standards.

Chloroquine Phosphate Tablets

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What is Chlordiazepoxide 10 mg used for?

In the pharmaceutical industry, Chlordiazepoxide Hydrochloride 10 mg is a landmark medication, being the first benzodiazepine ever developed. As a pharmacist, I characterize it as a long-acting anxiolytic and sedative-hypnotic that is particularly valued for its smooth onset and prolonged duration of action, which helps prevent the “rebound” effects seen with shorter-acting agents.

Primary Clinical Uses

  • Anxiety Disorders: Indicated for the short-term relief of severe anxiety or as a preoperative sedative to reduce patient apprehension.

  • Acute Alcohol Withdrawal: This is perhaps its most critical modern use. It is the “gold standard” for managing the symptoms of alcohol withdrawal (delirium tremens), helping to prevent seizures and agitation.

  • Psychosomatic Disorders: Used as adjunctive therapy in conditions where anxiety manifests as physical symptoms, such as in certain gastrointestinal or cardiovascular issues.

Mechanism of Action

Chlordiazepoxide works by enhancing the effect of the neurotransmitter GABA (Gamma-Aminobutyric Acid) in the central nervous system.

It binds to specific benzodiazepine receptors on the $GABA_A$ receptor complex. This binding increases the frequency of the opening of the chloride ion channel, leading to an influx of chloride ions into the neuron. This results in hyperpolarization of the post-synaptic neuron, making it less excitable and producing a calming, anti-convulsant, and muscle-relaxant effect.

The Manufacturer’s Perspective: Formulation & Export

From a manufacturing and global trade standpoint, Chlordiazepoxide 10 mg is a specialized CNS (Central Nervous System) product requiring strict regulatory oversight:

  • Controlled Substance Handling: As a WHO-GMP manufacturer, we maintain rigorous “Schedule” drug protocols. Exporting Chlordiazepoxide requires specific Export Permits and “No Objection Certificates” (NOC) from the Narcotics Commissioner.

  • Content Uniformity: Because it is effective at a 10 mg dose, we utilize validated high-shear granulation and blending to ensure every tablet in the batch is identical.

  • API Stability: Chlordiazepoxide is light-sensitive. Our manufacturing facility in Mumbai uses UV-protected environments during processing, and we prioritize opaque Alu-Alu or Amber PVC/PVDC blister packaging to ensure a stable 24-month shelf life.

  • Regulatory Readiness: We provide comprehensive CTD Dossiers and stability data to support our international partners in registering the product in African, Southeast Asian, and CIS markets.

Chlordiazepoxide Hydrochloride Tablets

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What is Cetirizine 10mg used for?

In the pharmaceutical industry, Cetirizine Hydrochloride 10 mg is a potent, second-generation receptor antagonist. As a pharmacist, I classify Cetirizine as a “non-sedating” antihistamine—though technically, it is “low-sedating” compared to first-generation drugs. Its primary value in a product portfolio lies in its rapid onset of action and its high selectivity for peripheral histamine receptors.

Primary Clinical Uses

  • Allergic Rhinitis: Effectively relieves symptoms of hay fever and seasonal allergies, including sneezing, rhinorrhea (runny nose), and post-nasal drip.

  • Chronic Urticaria (Hives): It is a frontline treatment for chronic idiopathic urticaria, reducing the number, size, and itching of wheals.

  • Allergic Conjunctivitis: Manages ocular symptoms such as redness, itching, and watering of the eyes caused by environmental allergens.

  • Dermatological Allergies: Often used as an adjunct to treat pruritus (itching) associated with insect bites or contact dermatitis.

Mechanism of Action

Cetirizine works by selectively inhibiting peripheral $H_1$ receptors. When an allergen enters the body, mast cells release histamine, which binds to $H_1$ receptors and causes vasodilation, increased capillary permeability, and itching.

Cetirizine competes with free histamine for binding sites on these receptors. Unlike first-generation antihistamines (like Chlorpheniramine), Cetirizine has poor penetration across the Blood-Brain Barrier (BBB), which is why it causes significantly less drowsiness while maintaining high peripheral efficacy.

The Manufacturer’s Perspective: Formulation & Export

From a manufacturing and global trade standpoint, Cetirizine is a high-volume OTC and prescription staple:

  • API Purity & Stability: As a WHO-GMP manufacturer, we ensure the Cetirizine HCl API meets stringent BP/USP/IP monographs, specifically monitoring for the “Related Substance A” impurity to ensure safety and shelf-life.

  • Formulation Versatility: We manufacture Cetirizine in various formats, including film-coated tablets, chewable tablets for pediatrics, and oral syrups. For the 10 mg tablets, we focus on a small, easy-to-swallow “breakline” design.

  • Packaging for Global Markets: To protect against the hygroscopic nature of the salt, we utilize PVC/PVDC or Alu-Alu blister packaging. This ensures the product remains stable for 24–36 months in Zone IVb (hot and humid) climates.

  • B2B & Tender Supply: Cetirizine is a core item for international B2B distributors. Our Mumbai-based facility provides complete CTD/eCTD Dossiers for rapid registration in global markets.

Cetrizine Tablets

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What are Carbimazole Tablets used for?

In the pharmaceutical industry, Carbimazole tablets (commonly manufactured in 5 mg and 20 mg strengths) are the frontline antithyroid agents used to manage an overactive thyroid gland. As a pharmacist, I characterize Carbimazole as a “prodrug” that provides a controlled, sustained reduction in the synthesis of thyroid hormones, restoring metabolic balance in patients with thyrotoxicosis.

Primary Clinical Uses

  • Hyperthyroidism: The primary treatment for an overactive thyroid, helping to alleviate symptoms like rapid heart rate, weight loss, and anxiety.

  • Graves’ Disease: Used to manage the autoimmune form of hyperthyroidism, often as part of a long-term “block and replace” or “titration” regimen.

  • Pre-operative Preparation: Administered to patients before a thyroidectomy (surgical removal of the thyroid) to ensure the patient is in a “euthyroid” (normal) state, reducing the risk of a thyroid storm during surgery.

  • Post-Radioactive Iodine Therapy: Used as an adjunct to stabilize thyroid levels while waiting for the effects of radioactive iodine treatment to manifest.

Mechanism of Action

Carbimazole is a prodrug that is rapidly converted in the body to its active metabolite, Methimazole. It works by inhibiting the enzyme thyroid peroxidase.

This enzyme is responsible for the iodination of tyrosine residues on thyroglobulin and the coupling of iodotyrosines to form $T_3$ (triiodothyronine) and $T_4$ (thyroxine). By blocking this process, Carbimazole effectively halts the production of new thyroid hormones without affecting the hormones already stored in the thyroid gland (which is why clinical improvement usually takes 1–3 weeks).

The Manufacturer’s Perspective: Formulation & Export

From a manufacturing and global trade standpoint, Carbimazole is a specialized endocrine product requiring high-tier quality standards:

  • Dose Precision: Because Carbimazole is potent and requires careful titration, as a WHO-GMP manufacturer, we ensure absolute content uniformity. Patients often start at high doses (20–60 mg) and maintenance can be as low as 5 mg.

  • Stability for Export: Carbimazole can be sensitive to environmental factors. We utilize Alu-Alu or high-grade PVC/PVDC blister packaging to ensure the product remains stable during transit to Zone IVb regions (Africa, SE Asia, and the Middle East).

  • B2B & Hospital Supply: This is a core item for endocrinology departments and specialized B2B distributors. Our Mumbai-based facility provides full CTD/eCTD Dossiers to support international registration.

  • Safety Monitoring: We adhere to strict API sourcing to ensure the highest purity, which is critical given the rare but serious risk of agranulocytosis (a drop in white blood cell count) associated with this class of drugs.

Carbimazole Tablets

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