Description
Torsemide Tablets
Healthy Inc is a specialized global supplier and exporter of advanced cardiovascular, nephrological, and intensive-care therapeutics. We provide ultra-high-purity, highly bioavailable Torsemide Tablets (5 mg / 10 mg / 20 mg / 100 mg), manufactured in WHO–GMP certified, high-precision oral solid dosage facilities. This “Advanced High-Ceiling Loop Diuretic” is a massive-volume, premium export to cardiology centers, dialysis clinics, geriatric care networks, and government health ministries in LATAM, the Middle East, Africa, and Southeast Asia, serving as the globally trusted, superior intervention for severe fluid retention (edema) associated with congestive heart failure, renal disease, and hepatic cirrhosis.
Product Overview
This formulation contains Torsemide, a highly potent pyridine-sulfonylurea class loop diuretic engineered to rapidly strip dangerous, life-threatening fluid buildup from the lungs and peripheral tissues.
The “Predictable Diuresis & Cardiac Defense” Specialist:
- Mechanism (Loop of Henle Blockade): Like all loop diuretics, Torsemide acts on the thick ascending limb of the loop of Henle in the kidneys. It aggressively binds to and shuts down the Na+/K+/2Cl- carrier system. By preventing the kidneys from reabsorbing sodium and chloride, it forces massive amounts of water to be excreted as urine, rapidly relieving pulmonary edema (fluid in the lungs) and swelling in the legs.
- The “Furosemide Upgrade” (Bioavailability): The older global standard, Furosemide, has notoriously erratic oral absorption (ranging wildly from 10% to 90%). This makes outpatient heart failure management incredibly difficult. Torsemide solves this completely with an incredibly stable oral bioavailability of 80% to 90%. An oral Torsemide tablet works almost as powerfully and predictably as an intravenous (IV) injection, significantly reducing hospital readmissions.
- The Anti-Aldosterone Advantage: Beyond just removing fluid, clinical data shows Torsemide actively inhibits the secretion of aldosterone. This prevents the severe potassium loss (hypokalemia) frequently caused by older diuretics and helps prevent harmful myocardial fibrosis (scarring of the heart muscle), actually improving long-term cardiac outcomes.
Product Composition & Strength
We supply this product as a Precision-Blended Uncoated Tablet, packed in highly secure, moisture-resistant Alu-PVC or opaque Alu-Alu blister strips, providing dosage flexibility for both mild hypertension and severe renal failure.
| Active Ingredient | Strength | Primary Clinical Use |
|---|---|---|
| Torsemide USP/Ph.Eur. | 5 mg / 10 mg | Standard maintenance therapy for mild-to-moderate congestive heart failure and essential hypertension. |
| Torsemide USP/Ph.Eur. | 20 mg | Acute diuresis for severe hepatic cirrhosis and advanced heart failure exacerbations. |
| Torsemide USP/Ph.Eur. | 100 mg | High-dose therapy specifically reserved for patients with severe chronic renal failure (CRF) and massive fluid overload. |
| Excipients | Lactose Monohydrate / Crospovidone / Magnesium Stearate | Diluent / Superdisintegrant / Lubricant (Engineered for immediate, predictable gastric dissolution) |
*Pack Sizes: 10×10 or 10×15 Blisters (Optimized for chronic cardiology and nephrology dispensing regimens).
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers, Cardiology Distributors, and Nephrology Networks.
| HS Code | 3004.90.99 (Medicaments containing other active substances – Diuretics/Cardiovascular) |
| CAS Number | 56211-40-6 |
| Dosage Form | Uncoated Tablet (Immediate Release) |
| Packaging | Alu-PVC or Alu-Alu Blisters. Protects the highly soluble API from environmental humidity, ensuring a stable, multi-year shelf life. |
| Storage | Store strictly below 30°C in a dry place. Protect from Light. |
| Certificates | WHO-GMP, COPP, Free Sale Certificate |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Predictable Dissolution Engineering: Because cardiologists prescribe Torsemide specifically for its reliable oral bioavailability, any fluctuation in tablet dissolution is clinically unacceptable. Our facilities utilize advanced high-shear granulation and strictly validated multipoint dissolution profiling to guarantee that every tablet releases the API with IV-equivalent kinetic predictability.
- Broad Dose Titration Output: From the low 5mg antihypertensive dose to the massive 100mg nephrology dose, our automated compression lines ensure absolute content uniformity across the entire spectrum, preventing dangerous dehydration or sub-therapeutic fluid retention.
Therapeutic Indications (Human Use)
Indicated for the comprehensive management of severe volume overload and cardiovascular strain:
- Congestive Heart Failure (CHF): Management of edema (fluid retention) associated with heart failure, drastically reducing pulmonary congestion and shortness of breath.
- Renal Disease: Management of severe edema associated with acute and chronic renal failure, including nephrotic syndrome.
- Hepatic Cirrhosis: Treatment of ascites (massive fluid accumulation in the abdomen) driven by severe liver disease (typically used in conjunction with aldosterone antagonists).
- Essential Hypertension: Treatment of high blood pressure, either as monotherapy or in combination with other antihypertensive agents.
Dosage & Administration
Recommended Dosage (Strictly as per Cardiologist/Nephrologist Guidelines):
- Administration (TIMING IS CRITICAL): Because this is a powerful “water pill,” it MUST be taken in the morning. If taken late in the afternoon or evening, the resulting profound diuresis will cause severe nocturia (frequently waking up to urinate), leading to debilitating insomnia for the patient.
- Food Independence: Can be taken with or without food; gastric contents do not significantly alter its high bioavailability.
Safety Warnings (CRITICAL Regulatory & Clinical Data):
- BLACK BOX EQUIVALENT (Profound Diuresis & Electrolyte Depletion): Torsemide is an incredibly potent diuretic. If given in excessive amounts, it can lead to profound water and electrolyte depletion, causing severe dehydration, dangerous drops in blood pressure (hypotension), and vascular thrombosis. Blood volume and electrolytes (Sodium, Potassium, Magnesium) must be carefully monitored.
- Sulfa Allergy Cross-Reactivity: Torsemide is a sulfonylurea derivative. It is generally contraindicated in patients with a known, severe anaphylactic allergy to sulfonamide antibiotics, as it may trigger a dangerous cross-reactive allergic cascade.
- Ototoxicity (Hearing Loss): Like all loop diuretics, rapid, high-dose administration or severe renal impairment can cause tinnitus (ringing in the ears) and temporary or permanent deafness. Note: Torsemide is generally considered to carry a lower risk of ototoxicity than Furosemide.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Retail Pharmacy Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Cardiovascular and Renal Formulations, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for intensive care programs in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.








Reviews
There are no reviews yet.