Description

Tolperisone Tablets (150 mg)

Healthy Inc is a specialized global supplier and exporter of advanced orthopedic, rheumatological, and neuromuscular therapeutics. We provide ultra-high-purity, highly bioavailable Tolperisone Hydrochloride Tablets (150 mg), manufactured in WHO–GMP certified, high-capacity oral solid dosage facilities. This “Non-Sedating Centrally Acting Muscle Relaxant” is a massive-volume, premium export to orthopedic centers, stroke rehabilitation clinics, primary care networks, and government health ministries in LATAM, the Middle East, Africa, and Southeast Asia, serving as the globally trusted intervention for acute, painful muscle spasms and post-neurological spasticity.

Product Overview

This formulation contains Tolperisone Hydrochloride, a highly advanced piperidine derivative that provides profound skeletal muscle relaxation while completely bypassing the cognitive and sedative side effects associated with legacy muscle relaxants.

The “Cognitive-Sparing Neuromuscular” Specialist:

• Mechanism (Brain Stem Blockade): Unlike traditional muscle relaxants that globally depress the central nervous system, Tolperisone operates specifically at the reticular formation in the brain stem. It aggressively blocks voltage-gated sodium and calcium channels, halting the hyperactive electrical signals traveling down the spinal cord to the muscles. This physically stops the muscle spasm at its neurological source.
• The “Non-Sedating” Clinical Advantage: The greatest barrier to treating daytime back pain or muscle spasms is that the medication puts the patient to sleep. Tolperisone is entirely devoid of affinity for adrenergic, cholinergic, or serotonergic receptors in the cerebral cortex. It completely preserves wakefulness, concentration, and motor coordination, allowing patients to safely drive, operate machinery, and return to work.
• Post-Stroke Rehabilitation: Beyond acute back pain, Tolperisone is globally mandated for the chronic management of severe, painful muscle spasticity following a cerebral stroke or spinal cord injury, making it a staple in long-term neurological rehab centers.

Product Composition & Strength

We supply this product as a Film-Coated Tablet, packed in highly secure, moisture-resistant Alu-PVC or opaque Alu-Alu blister strips, optimized for both acute 7-day dispensing and chronic rehabilitative regimens.

*Pack Sizes: 10×10 Blisters (Optimized for standard 150 mg thrice-daily orthopedic dispensing regimens).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers, Orthopedic Distributors, and Rehab Clinics.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Bioavailability Optimization: Tolperisone is highly susceptible to the “first-pass effect” in the liver, meaning poor formulation can lead to massive losses in clinical efficacy. Our facilities utilize advanced high-shear granulation and strictly validated multipoint dissolution profiling to guarantee rapid, complete absorption in the upper gastrointestinal tract, ensuring optimal plasma concentrations.

Therapeutic Indications (Human Use)

Indicated for the comprehensive management of pathological muscle tone and spasm:

• Acute Musculoskeletal Spasms: Symptomatic relief of painful, acute muscle spasms associated with spinal disorders (e.g., lumbago, sciatica, cervical syndrome, herniated discs).
• Neurological Spasticity: Treatment of pathologically elevated skeletal muscle tone following neurological damage, specifically post-stroke spasticity.

Dosage & Administration

Recommended Dosage (Strictly as per Physician/Orthopedic Guidelines):

• Standard Adult Dosing: 150 mg taken three times daily (TID), totaling 450 mg per day.
• Administration (FOOD REQUIREMENT IS CRITICAL): Tolperisone MUST be taken immediately after a meal with a glass of water. Taking the medication on an empty stomach drastically reduces its systemic bioavailability, severely compromising its muscle-relaxing efficacy.

Safety Warnings (CRITICAL Regulatory & Clinical Data):

• Hypersensitivity Reactions (Anaphylaxis): The most significant risk associated with Tolperisone is severe, potentially life-threatening hypersensitivity reactions, ranging from mild skin flushing and rash to severe anaphylactic shock (dyspnea, tachycardia, hypotension). Patients must be explicitly warned to stop the medication and seek emergency care if they experience facial swelling, wheezing, or a sudden drop in blood pressure.
• Cross-Reactivity: Females, older patients, and patients with a known history of allergies to other drugs (especially NSAIDs) or an allergy to Eperisone are at a significantly higher risk for hypersensitivity reactions.
• Renal & Hepatic Impairment: Because the drug is metabolized by the liver and excreted by the kidneys, dose adjustments or discontinuation may be required in patients with moderate-to-severe hepatic or renal impairment.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Retail Pharmacy Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Orthopedic and Neuromuscular Formulations, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for rehabilitation programs in Africa or a B2B Pharma Marketplace partner for Southeast Asia, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.