Timolol Eye Drops

Description

Timolol Maleate Ophthalmic Solution (0.5% w/v)

Healthy Inc is a specialized global supplier and exporter of advanced ophthalmology, geriatric vision care, and essential glaucoma therapeutics. We provide ultra-high-purity, kinetically stabilized Timolol Eye Drops, manufactured in WHO–GMP certified, high-precision sterile ophthalmic facilities. This “Non-Selective Beta-Adrenergic Blocker” is a massive-volume strategic export to retail pharmacies, eye hospitals, and government health ministries, serving as the globally trusted intervention for lowering intraocular pressure (IOP) in patients with open-angle glaucoma and ocular hypertension.

Product Overview

This formulation operates as a “Fluid Production Inhibitor.” It physically targets the “faucet” of the eye to reduce the volume of fluid entering the ocular globe, thereby preventing the pressure buildup that leads to optic nerve damage.

• Mechanism 1 ($\beta$-Adrenergic Receptor Blockade): Timolol physically blocks both $\beta_{1}$ and $\beta_{2}$ receptors in the ciliary epithelium.

• Mechanism 2 (Aqueous Inflow Reduction): By blocking these receptors, it physically reduces the rate of aqueous humor formation. It essentially “turns down the tap” rather than just opening the drain.

• Mechanism 3 (24-Hour IOP Control): Timolol provides a consistent and significant reduction in IOP (approx. 20–30%) with minimal effect on pupil size or visual acuity, making it ideal for long-term chronic management.

Product Composition & Strength

We supply this product in a Sterile, Buffered, Isotonic Aqueous Solution, optimized for high ocular tolerance and stability.

Technical & Logistics Specifications

• HS Code: 3004.90.99 (Medicaments acting on the sensory organs / Ophthalmic)

• CAS Number: 26921-17-5 (Timolol Maleate)

• Dosage Form: Sterile Eye Drops (Ophthalmic Solution)

• Packaging: Sterile LDPE Dropper Bottles (5ml). Our specialized ophthalmic packaging ensures 24-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Aseptic Filling Excellence: Our manufacturing process utilizes Class 100 (ISO 5) Sterile Filling Lines. This ensures the solution is 100% free from microbial contaminants, a non-negotiable requirement for patients who must use these drops for a lifetime.

• Global Standard Formulation: We utilize Standardized Maleate Salt Matrices to ensure bioequivalence with international brands, facilitating smooth registration in African, CIS, and SE Asian markets.

Primary Indications

• Ophthalmology: First-line treatment of Open-Angle Glaucoma and Ocular Hypertension.

• Secondary Glaucoma: Management of elevated pressure following ocular trauma or inflammation.

• Pediatrics: Used under specialist supervision for congenital glaucoma.

Dosage & Administration

• Standard Regimen: Typically 1 drop in the affected eye(s) twice daily (morning and evening).

• Administration: Apply to the conjunctival sac. To minimize systemic absorption, the patient should apply nasolacrimal occlusion (pressure on the tear duct) for 2 minutes after instillation.

• Duration: Chronic long-term use is standard; therapy should never be stopped without specialist advice.

Safety Warning: For Ophthalmic Use Only. Systemic Warning: As a beta-blocker, Timolol can be absorbed systemically. Use with extreme caution in patients with Asthma, COPD, or severe Heart Block/Failure. Vision Warning: May cause temporary blurred vision; do not drive until vision is clear. Contraindication: Do not use if known hypersensitivity to Timolol or beta-blockers exists.

Global Export & Contract Manufacturing

Healthy Inc is a premier Ophthalmic and Geriatric Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume sterile glaucoma therapeutics. Whether you are a National Health Ministry in Africa or a B2B Pharma Marketplace partner in the CIS, Middle East, or LATAM, we ensure secure, WHO-GMP compliant delivery.