Description

Tamsulosin Capsules

Healthy Inc is a specialized global supplier and exporter of advanced urological and geriatric care therapeutics. We provide high-purity Tamsulosin Hydrochloride Modified-Release Capsules (0.4 mg), manufactured in WHO–GMP certified advanced pelletization and oral solid dosage facilities. This “Uro-Selective Alpha-1 Blocker” is a massive-volume, highly strategic export to urology centers, geriatric clinics, surgical hospitals, and government health ministries in Africa, LATAM, and Southeast Asia, serving as the definitive, gold-standard intervention for Lower Urinary Tract Symptoms (LUTS) associated with Benign Prostatic Hyperplasia (BPH).

Product Overview

This formulation contains Tamsulosin Hydrochloride, a highly specific antagonist of alpha-1A and alpha-1D adrenoceptors.

The “Prostate & Bladder Neck” Specialist:

• Mechanism (Smooth Muscle Relaxation): The symptoms of an enlarged prostate (BPH) are heavily driven by the tension of smooth muscle in the prostate gland and the neck of the bladder. Tamsulosin binds aggressively to the alpha-1A receptors (which make up 70% of the alpha-receptors in the human prostate). By blocking these receptors, it physically relaxes the smooth muscle, drastically reducing urethral resistance, increasing maximum urinary flow rate, and relieving painful urinary retention.
• The “Uro-Selective” Advantage: Older alpha-blockers (like Prazosin or Terazosin) hit alpha-receptors indiscriminately across the entire body, causing severe drops in systemic blood pressure. Tamsulosin is “uro-selective”—it heavily targets the prostate while largely sparing the blood vessels. This allows elderly patients to experience rapid urinary relief without debilitating dizziness or fainting.
• Medical Expulsive Therapy (Off-Label): Beyond BPH, urologists globally procure massive volumes of Tamsulosin to help patients spontaneously pass distal ureteral stones (kidney stones), as the drug relaxes the smooth muscle of the ureter.

Product Composition & Strength

We supply this product as a Hard Gelatin Capsule containing Modified-Release (MR) Pellets, packed in specialized moisture-proof Alu-Alu blister strips.

*Pack Sizes: 10×10 Alu-Alu Blisters or 10×15 Alu-Alu Blisters (optimized for 30-day monthly urology dispensing cycles).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Urology Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Multi-Particulate Matrix Engineering: A “dose dump” of 0.4mg Tamsulosin into the bloodstream would cause dangerous hypotension. Our capsules contain hundreds of precisely engineered micro-pellets. Each pellet is coated with an advanced pH-dependent methacrylic acid polymer that slowly degrades as it travels through the GI tract, releasing the drug continuously over 24 hours to ensure stable, safe blood plasma levels.
• Assay & Dissolution Profiling: Rigorous 24-hour dissolution testing is performed via HPLC on every batch to guarantee that the API release curve strictly matches international pharmacopeial standards.

Therapeutic Indications (Human Use)

Indicated for the management of urological smooth muscle constriction:

• Benign Prostatic Hyperplasia (BPH): Treatment of the signs and symptoms of BPH (hesitancy, terminal dribbling, weak stream, urgency, nocturia).
• Medical Expulsive Therapy (Off-Label): Facilitates the spontaneous expulsion of distal ureteral calculi (kidney stones).

Dosage & Administration

Recommended Dosage (Strictly as per Urologist):

• Administration (TIMING IS CRITICAL): Should be administered once daily, approximately 30 minutes following the same meal each day. Fasting states significantly increase bioavailability and peak plasma concentrations, which raises the risk of adverse hypotensive effects.
• Standard Dose: One 0.4 mg capsule daily. (In rare cases, if a patient fails to respond after 2 to 4 weeks, the dose may be increased to 0.8 mg by the physician).
• Swallowing Protocol (CRITICAL): The capsule MUST be swallowed whole. It must not be crushed, chewed, or opened. Destroying the capsule compromises the modified-release pellets, leading to immediate dose-dumping and severe cardiovascular collapse.

Safety Warnings (CRITICAL):

• Intraoperative Floppy Iris Syndrome (IFIS): Tamsulosin paralyzes the dilator muscle of the iris. During cataract surgery, this causes the iris to become completely flaccid and billow (IFIS), vastly increasing surgical complication risks. Male patients MUST inform their ophthalmologist that they take Tamsulosin prior to eye surgery.
• Orthostatic Hypotension & Syncope: Although uro-selective, it can still cause a sudden drop in blood pressure upon standing up (postural hypotension), leading to dizziness or fainting (syncope), particularly during the first few days of therapy.
• Sulfa Cross-Reactivity: Rarely, patients with severe sulfonamide (“sulfa”) allergies may experience an allergic reaction to Tamsulosin.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Urological Formulations, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.