Description
Pheniramine Maleate Tablets (25 mg / 500 mg)
Healthy Inc is a specialized global supplier of high-stability allergy and respiratory therapies. We provide premium Pheniramine Maleate Tablets, manufactured in WHO–GMP certified formulation facilities. As a trusted first-generation antihistamine, this product is a primary export for emergency clinics, ENT centers, and general practitioners across Southeast Asia, Africa, and the Middle East.
Product Overview
Pheniramine Maleate is an alkylamine derivative that serves as a potent H1-receptor antagonist. It is specifically engineered to provide rapid relief from symptoms mediated by histamine release, including allergic rhinitis, urticaria, and pruritus.
The “Multi-Symptom” Allergy Specialist:
- Mechanism of Action: Pheniramine competitively inhibits histamine H1 receptors on effector cells. By blocking these sites, it prevents histamine-induced vasodilation, increased capillary permeability, and sensory nerve stimulation, effectively reducing redness, swelling, and itching.
- Anticholinergic Properties: Pheniramine possesses significant antimuscarinic activity. This provides a “drying effect” on nasal mucosa, making it highly effective for treating rhinorrhea (runny nose) associated with the common cold.
- Sedative Effect: As a first-generation antihistamine, it crosses the blood-brain barrier. While this causes drowsiness, it is clinically utilized to manage nighttime allergy symptoms and to provide relief in motion sickness.
Technical & Manufacturing Specifications
Formulated for rapid disintegration and high chemical purity.
| Technical Metric | Specification Standard |
|---|---|
| Active Ingredient | Pheniramine Maleate BP / USP / IP |
| Dosage Form | Uncoated or Film-Coated Tablets |
| Assay (Purity) | 98.0% – 101.0% |
| HS Code | 3004.90.39 (Antihistamines) / 2933.39.19 |
| Stability | Validated for Zone IVb (Hot and Humid) climates |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from ISO 9001:2015 certified units.
- Disintegration Optimization: Our tablets are engineered to disintegrate in less than 5 minutes, ensuring the active pharmaceutical ingredient is available for absorption as quickly as possible to manage acute allergic flares.
- Impurity Control: We strictly monitor for related substances and degradation products using validated HPLC methods, ensuring a high safety profile for use across various age groups.
- Standardized Coating: For our 25 mg tablets, we utilize a moisture-barrier film coating to prevent the hygroscopic maleate salt from degrading, ensuring a 36-month shelf life in tropical regions.
Therapeutic Indications & Clinical Symptoms
- Allergic Conditions: Relief from hay fever, allergic rhinitis, and vasomotor rhinitis.
- Dermatological Allergies: Treatment of urticaria (hives), pruritus, angioedema, and allergic eczema.
- Respiratory Adjunct: Symptomatic relief of the common cold by reducing sneezing and nasal discharge.
- Motion Sickness: Prevention and treatment of nausea and vomiting associated with travel.
Dosage & Administration
- Adult Dose: 25 mg taken 2 to 3 times daily, depending on the severity of symptoms.
- Safety Note: Due to its sedative nature, patients should be advised against operating heavy machinery or driving after consumption.
- Drug Interactions: Caution is required when used with CNS depressants, alcohol, or MAO inhibitors, as pheniramine may potentiate their effects.
Global Export & Contract Manufacturing Services
Healthy Inc is a verified Pharmaceutical Exporter in Mumbai, catering to NGO Health Programs and Ministry of Health Tenders. We offer Third Party Manufacturing for Pheniramine Maleate with full CTD Dossier and COPP support. Our logistics network ensures streamlined delivery to Vietnam, Nigeria, Kenya, and the Philippines, providing WHO-GMP quality at competitive B2B prices.
