Description

Pancreatin & L-Ornithine Tablets (170 mg / 150 mg)

Healthy Inc is a specialized global supplier and exporter of advanced gastroenterological, hepatoprotective, and biological enzyme therapeutics. We provide ultra-high-purity, kinetically synchronized Pancreatin (Enteric-Coated) & L-Ornithine Film-Coated Bilayer Tablets, manufactured in WHO–GMP certified, temperature- and humidity-controlled biological oral solid dosage facilities. This “Hepato-Pancreatic Synergy” is a highly lucrative, premium export to hepatology centers, gastroenterology clinics, rehabilitation networks, and government health ministries in LATAM, the CIS, Africa, and Southeast Asia, serving as the globally mandated intervention for combined hepatic impairment, hyperammonemia, and exocrine pancreatic insufficiency.

Product Overview

This highly advanced Fixed-Dose Combination masterfully synchronizes a live-action biological enzyme complex with a potent, liver-regenerating amino acid, delivering immediate digestive relief while actively reversing underlying hepatic toxicity.

The “Digestion & Detoxification” Specialist:

• Mechanism 1 (The Biological Digestion Catalyst – Pancreatin): In patients with severe liver disease (like cirrhosis or severe fatty liver), the production of bile drops, which exhausts the pancreas. Pancreatin physically replaces the missing enzymes: Lipase aggressively breaks down dietary fats, preventing severe bloating and steatorrhea; while Protease and Amylase dismantle proteins and starches, ensuring the malnourished patient actually absorbs the calories they consume.
• Mechanism 2 (The Ammonia Scavenger – L-Ornithine): A damaged liver loses its ability to filter toxic ammonia from the blood (a byproduct of protein breakdown), which can travel to the brain and cause confusion or coma (Hepatic Encephalopathy). L-Ornithine is a critical amino acid that forcefully activates the Urea Cycle in the liver. It physically binds to toxic ammonia and converts it into harmless urea, which is safely flushed out through the kidneys.
• The Hepato-Pancreatic Bridge: Treating the pancreas without supporting the liver in metabolic syndrome is a half-measure. By combining these two agents, you rapidly eliminate the physical discomfort of indigestion (gas, bloating, fat malabsorption) while simultaneously accelerating the regeneration of damaged liver cells (hepatocytes).

Product Composition & Strength

We supply this product as a Precision-Engineered Bilayer Tablet, packed exclusively in highly secure, moisture-resistant Alu-Alu blister strips to ensure the absolute stability of the biological proteins and the highly hygroscopic amino acid.

*Pack Sizes: 10×10 Alu-Alu Blisters (Optimized specifically for strict, high-compliance chronic hepato-gastro dispensing regimens).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers, Hepatology Distributors, and Hospital Procurement Boards.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Cold-Process Bilayer Segregation Engineering: Combining a live biological enzyme (Pancreatin) with a highly reactive amino acid salt (L-Ornithine) in a single tablet requires elite pharmaceutical segregation. If the two mix under compression, the amino acid will chemically degrade the enzymes. Our facilities utilize advanced Bilayer Rotary Presses under chilled, ultra-low humidity conditions. The Pancreatin layer is pre-coated with a specialized gastro-resistant polymer, completely isolating it from the immediate-release Ornithine layer, ensuring 100% biological activity reaches the intestines.

Therapeutic Indications (Human Use)

Indicated for the comprehensive management of combined hepatic and pancreatic metabolic dysfunction:

• Chronic Alcoholic Liver Disease: Management of liver damage, steatosis, and associated pancreatic exhaustion in patients with a history of chronic alcohol abuse.
• Non-Alcoholic Fatty Liver Disease (NAFLD / NASH): Treatment of liver inflammation and concurrent dyspepsia, bloating, and fat malabsorption.
• Hepatic Encephalopathy (Adjunct): Reduction of elevated blood ammonia levels in pre-cirrhotic or cirrhotic patients.
• Post-Cholecystectomy Syndrome: Relief of severe indigestion and metabolic imbalance following the surgical removal of the gallbladder.

Dosage & Administration

Recommended Dosage (Strictly as per Physician Guidelines):

• Standard Adult Dosing: 1 to 2 tablets taken orally two to three times daily, depending on the severity of the hepatic impairment and indigestion.
• Administration (THE MEALTIME RULE – CRITICAL): Because the Pancreatin must physically mix with food to break it down, the tablets MUST be swallowed whole during or immediately after a meal.
• The Intact Rule: Tablets must never be chewed or crushed. Crushing destroys the enteric coating on the Pancreatin, which will cause the active proteases to severely burn the mucosal lining of the mouth and esophagus.

Safety Warnings (CRITICAL Regulatory & Clinical Data):

• Severe Renal Impairment (Ammonia Clearance Risk): L-Ornithine converts ammonia into urea, which must then be excreted by the kidneys. In patients with severe, end-stage renal failure, the kidneys cannot clear the massive urea load, leading to systemic toxicity. It is contraindicated in severe renal impairment.
• Hyperuricemia & Gout: Porcine pancreatic extracts contain purines. High-dose therapy can significantly raise blood uric acid levels, potentially triggering acute gout attacks.
• Porcine Allergy: Strictly contraindicated in patients with a known hypersensitivity to pork proteins, as Pancreatin is a porcine-derived biological extract.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Hepatology Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Biological and Hepato-Gastro Formulations. Whether you are looking for a reliable Government Tender Supplier for liver disease clinics in the CIS or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely, secure delivery of highly stable, WHO-GMP certified products.