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Lamivudine Tablets
Lamivudine Tablets IP 100 mg
Each Filmcoated tablet contains :
Lamivudine IP 100 mg exceipents Q.S.
Lamivudine Tablets IP 150 mg
Each Filmcoated tablet contains :
Lamivudine IP 150 mg
Lamivudine 150 mg + Zidovudine 300 mg + Nevirapine 200 mg tablets IP Each Film Coated Tablets Contains: Lamivudine IP 150 mg Zidovudine IP 300 mg Nevirapine IP 200 mg Excipients Q.S.
Lamuzy Tablets Lamivudine and Zidovudine Tablets IP
Each Film Coated tablet contains :
Zidovudine IP 300 mg
Lamivudine IP 150 mg
Cirolam 150 Tablets
Lamivudine Tablets 150 mg
Each Film Coated tablet contains :
Lamivudine USP 150 mg
Usage: – Hepatitis B infection
Category: – HIV Anti Viral drugs
Therapeutic category: – Antiviral, Anti HIV, Hepatitis Treatment
Description
Lamivudine Tablets (100 mg / 150 mg / 300 mg)
Healthy Inc is a specialized global supplier of high-stability antiretroviral and antiviral therapies. We provide premium Lamivudine Tablets, manufactured in WHO–GMP certified dedicated antiviral blocks. As an essential component of HIV and Hepatitis B management, this product is a primary export for infectious disease centers, HIV/AIDS clinics, and Ministry of Health (MOH) tenders in Southeast Asia, Africa, and the CIS region.
Product Overview
Lamivudine (3TC) is a synthetic nucleoside analogue with potent activity against Human Immunodeficiency Virus Type 1 (HIV-1) and Hepatitis B Virus (HBV). It is engineered to be incorporated into viral DNA, acting as a definitive chain terminator to stop viral replication.
The “Replication Inhibitor” Specialist:
- Mechanism of Action: Lamivudine is phosphorylated intracellularly to its active metabolite, lamivudine triphosphate. This metabolite competes with natural substrates for Viral Reverse Transcriptase (in HIV) and HBV Polymerase. Once incorporated into the growing DNA chain, it lacks the 3′-hydroxyl group necessary for further linkage, resulting in premature DNA chain termination.
- Synergistic Versatility: In HIV therapy, Lamivudine is rarely used alone; it is a foundational “backbone” agent used in combination with other antiretrovirals (like Zidovudine or Tenofovir) to prevent drug resistance and maximize viral suppression.
- Hepatitis B Efficacy: At lower dosages (100 mg), it is a potent treatment for Chronic Hepatitis B, significantly reducing viral load and improving liver histology and transaminase levels.
Technical & Manufacturing Specifications
Formulated for high absorption and long-term chemical stability.
| Technical Metric | Specification Standard |
|---|---|
| Active Ingredient | Lamivudine BP / USP / IP |
| Dosage Form | Film-Coated Tablets |
| Available Strengths | 100 mg (HBV), 150 mg, 300 mg (HIV) |
| HS Code | 3004.90.99 (Antivirals) / 2934.99.90 |
| Stability | Validated for Zone IVb (Hot/Humid) climates |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from ISO 9001:2015 certified units.
- High Enantiomeric Purity: Lamivudine is the negative enantiomer of a thiacytidine analogue. Our manufacturing ensures 100% chiral purity, as the specific $(-)$ enantiomer provides the highest therapeutic index with the lowest toxicity.
- Advanced Coating: We utilize specialized moisture-barrier film coatings to protect the API from hydrolysis, ensuring the product remains stable for 36 months in tropical export environments.
- Bioequivalence Standards: Every batch is tested to ensure the dissolution profile and pharmacokinetic parameters ($C_{max}$ and $AUC$) match the innovator brand (Epivir/Zeffix), ensuring predictable viral suppression.
Therapeutic Indications & Clinical Symptoms
- HIV-1 Infection: Part of Highly Active Antiretroviral Therapy (HAART) for the treatment of HIV-infected adults and children.
- Chronic Hepatitis B: Management of patients with compensated liver disease and evidence of active viral replication.
- Post-Exposure Prophylaxis (PEP): Used in combination with other agents following potential exposure to HIV.
Dosage & Administration
- HIV Dose: Typically 300 mg daily (as a single dose or 150 mg twice daily).
- HBV Dose: 100 mg once daily.
- Administration: Can be taken with or without food.
- Safety Note: Dosage must be adjusted in patients with renal impairment ($CrCl < 50$ mL/min). Patients co-infected with HIV and HBV must use HIV-appropriate doses to avoid the development of resistant HBV strains.
Global Export & Contract Manufacturing Services
Healthy Inc is a verified Pharmaceutical Exporter in Mumbai, catering to NGO Health Missions, HIV Programs, and Ministry of Health Tenders. We offer Third Party Manufacturing for Lamivudine with full CTD Dossier and COPP support. Our logistics network ensures secure transit to Vietnam, Nigeria, South Africa, and the Philippines, providing WHO-GMP quality at competitive B2B prices.
Commercial Inquiries
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
