Description
Ciprofloxacin Tablets
Healthy Inc is a specialized global supplier and exporter of high-potency fluoroquinolone antibiotics. We provide high-purity Ciprofloxacin Tablets (Hydrochloride), sourced from WHO–GMP certified solid dosage facilities. This “Broad-Spectrum Bactericidal” agent is a top export to hospital formularies, infectious disease centers, and government procurement agencies in Africa, LATAM, and Southeast Asia, serving as the frontline defense against life-threatening Gram-negative infections, particularly Typhoid Fever and complicated Urinary Tract Infections (UTIs).
Product Overview
This formulation contains Ciprofloxacin Hydrochloride, a second-generation fluoroquinolone with superior tissue penetration.
The “DNA Stopper” Specialist:
- Mechanism: Ciprofloxacin is bactericidal (kills bacteria). It works by inhibiting two essential bacterial enzymes: DNA Gyrase (Topoisomerase II) and Topoisomerase IV. These enzymes are responsible for uncoiling and recoiling bacterial DNA during replication. By blocking them, Ciprofloxacin causes the bacterial DNA to break and fail to replicate, leading to rapid cell death.
- Gram-Negative Dominance: It is exceptionally potent against Gram-negative aerobic bacteria, including Pseudomonas aeruginosa, Salmonella typhi (Typhoid), E. coli, and Shigella.
- Tissue Penetration: It achieves high concentrations in the kidneys, prostate, lung tissue, and bile, often exceeding plasma levels, making it ideal for deep-seated infections.
- Anthrax Defense: It is a primary drug of choice for post-exposure prophylaxis of inhalational Anthrax.
Product Composition & Strength
We supply this product as Film Coated Tablets. The coating is non-negotiable due to the extreme bitterness of the API and its light sensitivity.
| Active Ingredient | Strength (Standard) | Primary Role |
|---|---|---|
| Ciprofloxacin HCl USP/BP | 250 mg | Uncomplicated UTI / Mild Infection |
| Ciprofloxacin HCl USP/BP | 500 mg | Typhoid / Respiratory / Abdominal |
| Ciprofloxacin HCl USP/BP | 750 mg | Severe / Bone & Joint / Pseudomonas |
| Excipients | Q.S. | Titanium Dioxide (Opacifier) / Hypromellose |
*Pack Sizes: Blister packs of 10s (Box of 10×10), 14s, 20s, or Bulk HDPE Jars of 500s/1000s.
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.20.19 (Medicaments containing other antibiotics) |
| Dosage Form | Film Coated Tablet (Oral) |
| Packaging | PVC-Alu Blister or Alu-Alu Blister (Light Sensitive) |
| Storage | Store below 25°C. Protect from Light. |
| Certificates | WHO-GMP, COPP, Free Sale Certificate |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Taste Masking Engineering: Ciprofloxacin is one of the most bitter substances in pharmacopeia. An uncoated tablet would induce immediate gagging. Our manufacturing process ensures a robust, tasteless film coating that survives handling but dissolves rapidly in the stomach.
- Photostability: The molecule degrades rapidly under UV light. We use opaque blisters and specific opacifiers (Titanium Dioxide) in the coating to ensure stability in high-sunlight export regions (like Africa).
Therapeutic Indications (Human Use)
Indicated for the treatment of moderate to severe bacterial infections:
- Typhoid Fever (Enteric Fever): Caused by Salmonella typhi.
- Urinary Tract Infections (UTI): Acute cystitis and complicated pyelonephritis.
- Infectious Diarrhea: Traveler’s diarrhea, Shigellosis, and Cholera.
- Bone & Joint Infections: Osteomyelitis (requires high dose 750mg and long duration).
- Respiratory Tract: Pneumonia caused by Gram-negative bacteria (e.g., Klebsiella, Pseudomonas).
Dosage & Administration
Recommended Dosage (Strictly as per Physician):
- Route: Oral.
- Uncomplicated UTI: 250 mg to 500 mg twice daily.
- Typhoid Fever / Infectious Diarrhea: 500 mg twice daily for 5 to 7 days.
- Severe / Bone Infections: 750 mg twice daily (every 12 hours).
- The “2-Hour Rule” (CRITICAL):
- Chelation: Ciprofloxacin binds to Calcium, Magnesium, Iron, and Zinc, forming insoluble complexes that cannot be absorbed.
- Avoid: Do not take with milk, yogurt, calcium-fortified juice, antacids, or iron supplements. Space doses by at least 2 hours.
- Hydration: Patients must drink plenty of water to prevent crystalluria (drug crystals forming in urine).
Safety Warnings:
- Tendon Rupture (Black Box Warning): Fluoroquinolones increase the risk of tendonitis and tendon rupture (especially the Achilles tendon). Risk is higher in elderly patients and those on steroids.
- Phototoxicity: Causes moderate to severe skin sensitivity to sunlight. Avoid sun exposure.
- CNS Effects: Can cause dizziness, confusion, and lower the seizure threshold. Use caution in epileptics.
- Pediatrics: Generally avoided in children under 18 due to risk of cartilage damage in weight-bearing joints (except in critical cases like Anthrax or Cystic Fibrosis).
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.
