Description

Cephalexin Capsules

Healthy Inc is a specialized global supplier and exporter of essential broad-spectrum beta-lactam antimicrobials. We provide high-purity Cephalexin Capsules (250 mg / 500 mg), manufactured in WHO–GMP certified, completely dedicated cephalosporin oral solid dosage facilities. This “First-Generation Cephalosporin” is a massive-volume, foundational export to primary care clinics, dermatology centers, pediatric hospitals, and government health ministries in Africa, LATAM, and Southeast Asia, serving as the gold-standard oral intervention for skin and soft tissue infections, respiratory tract infections, and uncomplicated UTIs.

Product Overview

This formulation contains Cephalexin (as Cephalexin Monohydrate), a highly bioavailable, first-generation cephalosporin antibiotic.

The “Primary Care & Skin” Specialist:

• Mechanism (Cell Wall Synthesis Blockade): Like all beta-lactams, Cephalexin is bactericidal. It easily penetrates the bacterial cell envelope and binds to specific Penicillin-Binding Proteins (PBPs) located inside the bacterial cell wall. It halts the final stage of peptidoglycan cross-linking, physically weakening the cell wall until osmotic pressure causes the bacteria to burst (lyse).
• First-Generation Spectrum: Cephalexin is highly lethal against Gram-positive cocci, particularly Methicillin-Susceptible Staphylococcus aureus (MSSA) and Group A beta-hemolytic Streptococci. It also possesses targeted activity against specific community-acquired Gram-negative bacilli (like E. coli and Klebsiella pneumoniae).
• Exceptional Bioavailability & Safety: It is rapidly and almost completely absorbed from the gastrointestinal tract (near 100% bioavailability), providing fast, reliable peak serum levels. Furthermore, it is widely considered safe for use during pregnancy (Category B), making it a massive procurement priority for maternal and family health clinics.

Product Composition & Strength

We supply this product as a Hard Gelatin Capsule, packed in moisture-resistant Alu-PVC or Alu-Alu blister strips.

*Pack Sizes: 10×10 Alu-PVC Blisters or Bulk Jars of 500/1000 Capsules for high-volume institutional dispensing.

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Primary Care Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Dedicated Cephalosporin Isolation: Regulatory guidelines strictly prohibit manufacturing cephalosporins in the same facilities as penicillins or general non-antibiotic drugs. Our Cephalexin is processed in a 100% isolated manufacturing block featuring independent HVAC units and dedicated machinery to completely eliminate the risk of fatal anaphylactic cross-contamination.
• Rapid Dissolution Profiling: The monohydrate salt and premium disintegrants ensure the capsule shell ruptures rapidly in the gastric environment, typically achieving peak plasma concentrations within 1 hour of administration.

Therapeutic Indications (Human Use)

Indicated for the treatment of community-acquired bacterial infections:

• Skin and Soft Tissue Infections (SSTIs): Cellulitis, impetigo, wound infections, and severe furunculosis (staphylococcal and streptococcal).
• Respiratory Tract Infections: Streptococcal pharyngitis, tonsillitis, and mild-to-moderate community-acquired pneumonia.
• Genitourinary Tract Infections: Uncomplicated cystitis and acute prostatitis.
• Bone and Joint Infections: Osteomyelitis (often used as oral step-down therapy after IV antibiotics).

Dosage & Administration

Recommended Dosage (Strictly as per Physician):

• Administration: Taken orally, with or without food. (Taking it with food may slightly delay the peak absorption time but does not decrease the total amount of drug absorbed, and can help minimize GI upset).
• Standard Adult Dose: 250 mg every 6 hours, or 500 mg every 12 hours.
• Severe Infections (Adults): Up to 4 grams daily, administered in divided doses.
• Renal Impairment: Because Cephalexin is excreted primarily unchanged by the kidneys, dosing intervals must be extended in patients with significantly impaired renal function.

Safety Warnings (CRITICAL):

• Penicillin Cross-Reactivity: Cephalosporins share structural similarities with penicillins. Approximately 5% to 10% of patients with a documented Penicillin allergy will also experience a hypersensitivity reaction to Cephalexin. It should be used with extreme caution in these patients, and is strictly contraindicated in patients who have a history of Penicillin-induced anaphylaxis.
• Gastrointestinal Disruption: Can significantly alter normal gut flora, leading to antibiotic-associated diarrhea or, in severe cases, Clostridioides difficile-associated colitis (CDAC).
• Direct Coombs Test: May cause a false-positive direct Coombs test, which can complicate blood cross-matching protocols.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Dedicated Cephalosporin Formulations, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.