Description

Ceftriaxone Sodium Injection 1g

Healthy Inc is a specialized global supplier and exporter of high-volume third-generation cephalosporins. We provide high-purity Ceftriaxone Sodium Injection (1 g), sourced from WHO–GMP certified sterile injectable facilities. This “Once-Daily Wonder” is a top export to infectious disease wards, government hospitals, and health ministries in Africa, LATAM, and Southeast Asia, serving as the absolute backbone of hospital antibiotic therapy for severe community-acquired and nosocomial infections.

Product Overview

This formulation contains Ceftriaxone Sodium, a broad-spectrum cephalosporin distinguished by its exceptionally long half-life and dual mode of excretion.

The “Once-Daily” Specialist:

• Pharmacokinetics (24-Hour Coverage): Ceftriaxone has an elimination half-life of approximately 8 hours, the longest of all cephalosporins. This allows for Once-Daily Dosing, which significantly reduces nursing workload and costs in overcrowded hospital wards compared to drugs requiring 3-4 doses a day.
• CNS Penetration (Meningitis): It readily crosses the blood-brain barrier when meninges are inflamed. It is the Drug of Choice for empiric treatment of bacterial meningitis caused by N. meningitidis, S. pneumoniae, and H. influenzae.
• Dual Excretion: Unlike most cephalosporins which are purely renal, Ceftriaxone is excreted 50% by the kidneys and 50% by the liver (bile). This makes it safer for patients with renal impairment, often requiring no dose adjustment.

Product Composition & Strength

We supply this product as a Sterile Dry Powder for Injection in glass vials.

*Pack Sizes: Tray of 1 Vial, 10 Vials, 50 Vials, or Box of 1/10 Vials with Water for Injection (WFI).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Sterile Micronization: We use sterile micronized powder to ensure the 1g cake dissolves rapidly (within 60 seconds) upon adding water. This prevents “caking” at the bottom of the vial, ensuring the patient receives the full dose.
• Color Stability: Our manufacturing lines use nitrogen flushing to prevent oxidation. The powder remains white to pale yellow. Any orange or brown discoloration indicates degradation, which our QC strictly rejects.

Therapeutic Indications (Human Use)

Indicated for the treatment of severe infections:

• Bacterial Meningitis: First-line empirical therapy.
• Community-Acquired Pneumonia (CAP): Hospitalized patients.
• Typhoid Fever: For multidrug-resistant Salmonella typhi.
• Gonorrhea: Uncomplicated (usually lower dose) and disseminated.
• Lyme Disease: Neurological (Neuroborreliosis) or cardiac involvement.
• Intra-abdominal Infections: Peritonitis (with Metronidazole).

Dosage & Administration

Recommended Dosage (Strictly as per Physician):

• Route: Intravenous (IV) Infusion or Deep IM Injection.
• Adults (Standard): 1 g to 2 g once daily.
• Meningitis: 2 g every 12 hours (Max 4 g/day).
• Gonorrhea: 250-500 mg Single IM Dose.
• Surgical Prophylaxis: 1 g IV single dose 30-120 mins before surgery.
• Reconstitution: Dissolve 1g vial in 10ml WFI/Saline for IV or 3.5ml 1% Lidocaine for IM.

Safety Warnings (CRITICAL):

• Calcium Interaction (FATAL PRECIPITATION): NEVER mix Ceftriaxone with Calcium-containing solutions (e.g., Ringer’s Lactate, Hartmann’s Solution, TPN). It forms insoluble crystals in the lungs and kidneys, which can be fatal. CONTRAINDICATED in Neonates requiring calcium.
• Kernicterus: CONTRAINDICATED in Neonates (< 28 days), especially prematures. It displaces bilirubin from albumin, leading to brain damage.
• Gallbladder Sludge: High doses can cause reversible biliary pseudolithiasis (sludge).

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Sterile Injectables, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.