Description
Azithromycin & Cefixime Tablets (250 mg / 200 mg)
Healthy Inc is a specialized global supplier and exporter of advanced anti-infectives, internal medicine, and targeted respiratory therapeutics. We provide ultra-high-purity, kinetically balanced Azithromycin & Cefixime FDC Tablets, manufactured in WHO–GMP certified, high-precision specialized antibiotic containment facilities. This “Macrolide & Cephalosporin FDC” is a massive-volume strategic export to infectious disease hospitals, rural health clinics, and government health ministries, serving as the globally mandated intervention for resistant Respiratory Tract Infections (RTIs), Uncomplicated Gonorrhea, and Enteric Fever (Typhoid).
Product Overview
This formulation operates as a “Dual-Front Offensive” against bacterial pathogens. By combining a cell-wall disruptor (Cefixime) with a protein-synthesis inhibitor (Azithromycin), the FDC ensures that even bacteria resistant to one mechanism are neutralized by the other.
Mechanism 1 (The Wall Breaker – Cefixime): As a 3rd-generation Cephalosporin, Cefixime binds to Penicillin-Binding Proteins (PBPs). This inhibits the final transpeptidation step of peptidoglycan synthesis, physically causing the bacterial cell wall to rupture and the cell to die (Bactericidal).
Mechanism 2 (The Protein Blocker – Azithromycin): As an Azalide/Macrolide, Azithromycin binds to the 50S ribosomal subunit. It blocks the translocation of peptides, physically stopping the bacteria from producing the proteins it needs to grow and multiply (Bacteriostatic).
Mechanism 3 (The Synergistic Spectrum): This combination covers a vast range of pathogens, including Gram-positive, Gram-negative, and “atypical” bacteria (like Chlamydia and Mycoplasma), making it the “Gold Standard” for empirical therapy where the specific pathogen is unknown.
Product Composition & Strength
We supply this product as a Precision-Blended, Film-Coated Tablet, packed in high-barrier Alu-Alu blister strips to prevent the degradation of the moisture-sensitive API.
| Active Ingredient | Strength | Primary Clinical Function |
| Cefixime (as Trihydrate) USP/BP | 200 mg | The Gram-Negative Specialist: Targets the cell walls of stubborn bacteria, highly effective in Typhoid and Bronchitis. |
| Azithromycin (as Dihydrate) USP/BP | 250 mg / 500 mg | The Tissue-Penetrating Anchor: Provides prolonged activity in the lungs and soft tissues to eliminate intracellular pathogens. |
| Excipients | Proprietary Matrix | Dual-Release System: Engineered to ensure synchronized absorption of both antibiotics despite their different chemical solubilities. |
Technical & Logistics Specifications
HS Code: 3004.20.19 (Medicaments containing other antibiotics – Cefixime/Azithromycin)
CAS Numbers: 79350-37-1 (Cefixime) / 83905-01-5 (Azithromycin)
Dosage Form: Film-Coated Tablet (Large, capsule-shaped for easy swallowing)
Packaging: Alu-Alu Blisters (MANDATORY). Azithromycin is hygroscopic; our moisture-lock packaging ensures 24-month stability in Zone IVb tropical climates.
Manufacturing Authority & Compliance
Dedicated Antibiotic Containment: We utilize Segregated Beta-Lactam Production Blocks to manufacture Cefixime, ensuring zero cross-contamination with the Macrolide section, meeting the strictest international regulatory standards.
Bioequivalence Mastery: We provide comprehensive dissolution data to prove that our FDC matches the combined pharmacokinetic profile of the individual originator brands, ensuring a predictable “Kill-Curve.”
Primary Indications
Respiratory: Community-Acquired Pneumonia (CAP), Acute Bronchitis, and Sinusitis.
Infectious Disease: Enteric Fever (Typhoid) resistant to monotherapy and Uncomplicated Gonorrhea.
ENT: Severe Pharyngitis, Tonsillitis, and Otitis Media.
Dosage & Administration
Standard Adult Dosing: 1 tablet once daily for 3 to 5 days, or as directed by an infectious disease specialist.
The “One Hour” Rule: For maximum absorption of Azithromycin, it is often recommended to take the tablet 1 hour before or 2 hours after a meal.
Safety Warning: Risk of Clostridioides difficile-associated diarrhea. Use with caution in patients with hepatic impairment or a history of QT prolongation (cardiac risk). Complete the full course of therapy to prevent the development of multidrug-resistant bacteria.
Global Export & Contract Manufacturing
Healthy Inc is a premier Antibiotic Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-potency Antibiotic FDCs. Whether you are a Government Tender Buyer in Africa or a B2B Pharma Marketplace partner in the CIS, we ensure secure, WHO-GMP compliant delivery.
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