Description
Amlodipine Besylate Tablets
Healthy Inc is a specialized global supplier and exporter of primary cardiovascular agents. We provide high-purity Amlodipine Besylate Tablets, sourced from WHO–GMP certified solid dosage facilities. This “Long-Acting” Calcium Channel Blocker is a top export to cardiology centers, hypertension clinics, and government health formularies in Africa, LATAM, and Southeast Asia, serving as a first-line therapy for blood pressure control and angina management.
Product Overview
This formulation contains Amlodipine Besylate, a dihydropyridine calcium antagonist (calcium channel blocker or CCB).
The “Vascular Selective” Specialist:
- Vascular Selectivity: Unlike non-dihydropyridines (like Verapamil), Amlodipine has a greater effect on vascular smooth muscle cells than on cardiac muscle cells. It relaxes the peripheral arteries, lowering peripheral vascular resistance and reducing blood pressure.
- Angina Relief:
- Stable Angina: Reduces the “afterload” (resistance) the heart must pump against, lowering oxygen demand.
- Prinzmetal’s (Variant) Angina: Prevents spasms of the coronary arteries, restoring blood flow to the heart muscle.
- Once-Daily Dosing: With a unique long half-life (30–50 hours), it provides consistent 24-hour control with a single daily dose, avoiding the “peaks and valleys” seen with shorter-acting drugs.
- Metabolic Neutrality: Does not negatively impact lipid levels or glucose metabolism, making it safe for diabetic and dyslipidemic patients.
Product Composition & Strength
We supply this product as Uncoated Tablets (White/Off-White). The strength refers to the free base Amlodipine.
| Active Ingredient | Strength (Standard) | Role |
|---|---|---|
| Amlodipine Besylate USP/BP | 2.5 mg | Geriatric / Hepatic Impairment |
| Amlodipine Besylate USP/BP | 5 mg | Standard Adult Dose |
| Amlodipine Besylate USP/BP | 10 mg | High Potency Dose |
| Excipients | Q.S. | Microcrystalline Cellulose (Filler) |
*Pack Sizes: Blister packs of 10s, 14s (Calendar Pack), 28s, or Bulk Jars of 1000s.
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.90.99 (Other Medicaments) |
| Dosage Form | Tablet (Oral) |
| Packaging | PVDC-Alu Blister or Alu-Alu Blister (Light Sensitive) |
| Storage | Store below 25°C. Protect from Light. |
| Certificates | WHO-GMP, COPP, Free Sale Certificate |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Photostability: Amlodipine is extremely sensitive to light (photolabile) and degrades into pyridine derivatives if exposed. We use opaque blisters (White PVC or Alu-Alu) to ensure the product remains stable until consumption.
- Dissolution: Our formulation ensures rapid disintegration and dissolution (>85% in 30 mins) to guarantee consistent bioavailability.
Therapeutic Indications (Human Use)
Indicated for the treatment of:
- Hypertension: Alone or in combination with other antihypertensive agents (Thiazides, ACE inhibitors, ARBs).
- Chronic Stable Angina: For symptomatic relief of chest pain.
- Vasospastic Angina (Prinzmetal’s): Confirmed or suspected coronary artery spasm.
- Angiographically Documented CAD: To reduce the risk of hospitalization for angina and coronary revascularization procedures.
Dosage & Administration
Recommended Dosage (Strictly as per Cardiologist/Physician):
- Route: Oral.
- Adults (Standard): Initiate with 5 mg once daily. Dosage may be increased to a maximum of 10 mg depending on patient response.
- Small, Fragile, or Elderly Patients: Initiate with 2.5 mg once daily.
- Hepatic Insufficiency: Amlodipine is extensively metabolized by the liver. Patients with liver failure should start at 2.5 mg.
- Timing: Can be taken without regard to meals.
Safety Warnings:
- Peripheral Edema: Commonly causes swelling of the ankles/feet due to precapillary vasodilation. This is dose-dependent (more common at 10 mg).
- Hypotension: Symptomatic low blood pressure is rare but possible, especially in patients with severe aortic stenosis.
- Heart Failure: Use with caution in patients with heart failure.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.
Commercial Inquiries
For hospital tenders, bulk export, or distributor pricing, please contact our export team.
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
