Description

Acetazolamide Tablets

Healthy Inc is a specialized global supplier and exporter of essential ophthalmic and diuretic agents. We provide high-purity Acetazolamide Tablets, sourced from WHO–GMP certified solid dosage facilities. This “Pressure Reducer” Carbonic Anhydrase Inhibitor is a top export to ophthalmology clinics, mountaineering institutes, and neurology wards in Africa, LATAM, and Southeast Asia, serving as the standard emergency treatment for Glaucoma and the primary prophylaxis for Acute Mountain Sickness (AMS).

Product Overview

This formulation contains Acetazolamide, a non-bacteriostatic sulfonamide derivative.

The “Fluid Control” Specialist:

• Mechanism: Acetazolamide is a potent inhibitor of Carbonic Anhydrase, the enzyme that catalyzes the reversible hydration of carbon dioxide and the dehydration of carbonic acid.
• Eye Pressure (Glaucoma): In the eye, blocking this enzyme reduces the secretion of Aqueous Humor (fluid inside the eye) by 50–60%, drastically lowering Intraocular Pressure (IOP).
• Mountain Sickness: It forces the kidneys to excrete bicarbonate, creating a mild metabolic acidosis. This stimulates the respiratory drive, causing deeper and faster breathing (hyperventilation), which increases blood oxygen levels at high altitudes.
• Edema/Epilepsy: It acts as a mild diuretic and has anticonvulsant properties useful in certain refractory epilepsies.

Product Composition & Strength

We supply this product as Uncoated Tablets (White, round). The 250 mg strength is the universal standard.

*Pack Sizes: Blister packs of 10s (Box of 10×10), 15s, 30s, or Bulk HDPE Jars of 1000s (Hospital Packs).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Particle Size Control: Acetazolamide has poor water solubility. We use micronized API to ensure adequate dissolution and rapid absorption, critical for reducing eye pressure quickly in acute angle-closure glaucoma attacks.
• Cross-Contamination: As a sulfonamide derivative, it can cause severe allergies. We manufacture in segregated suites to prevent contamination of non-sulfa products.

Therapeutic Indications (Human Use)

Indicated for fluid retention and pressure control:

• Glaucoma: Chronic simple (open-angle) glaucoma, secondary glaucoma, and pre-operatively in acute angle-closure glaucoma (to delay surgery).
• Acute Mountain Sickness (AMS): Prevention and amelioration of symptoms (headache, nausea, dizziness) when climbing above 3000m.
• Edema: Adjunctive treatment of edema due to congestive heart failure or drugs.
• Epilepsy: Adjunct in centrencephalic epilepsies (petit mal, unlocalized seizures).

Dosage & Administration

Recommended Dosage (Strictly as per Physician):

• Route: Oral.
• Glaucoma (Open Angle): 250 mg to 1000 mg per day in divided doses (usually 250 mg 1-4 times daily).
• Acute Mountain Sickness: 250 mg twice daily (500 mg/day).
  • Timing: Start 24–48 hours before ascent and continue for 48 hours at high altitude.
• Edema: 250 mg to 375 mg once daily in the morning (for 2 days, then skip a day to regain effect).
• Administration: Take with food to reduce GI upset. Drink plenty of fluids to prevent kidney stones.

Safety Warnings:

• Sulfa Allergy (CRITICAL): Acetazolamide is a sulfonamide. Contraindicated in patients with severe allergy to sulfa drugs.
• Kidney Stones: Increases the risk of calcium phosphate/oxalate stones due to urinary alkalinization.
• Paresthesia: Common side effect involves tingling/numbness in fingers, toes, and lips.
• Electrolytes: Causes loss of Potassium (Hypokalemia). Monitor electrolytes if used long-term.
• Drowsiness: May cause drowsiness or myopia (nearsightedness) which resolves upon stopping.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.

Commercial Inquiries

For hospital tenders, bulk export, or distributor pricing, please contact our export team.

WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in