Vildagliptin Tablets

Healthy Inc is a specialized global supplier and exporter of advanced endocrinology, metabolic, and modern glycemic control therapeutics. We provide high-purity, precision-dosed Voglibose Tablets (Correction: Vildagliptin Tablets) Vildagliptin Tablets (50 mg), manufactured in WHO–GMP certified, high-capacity oral solid dosage facilities. This “Modern Incretin Enhancer (DPP-4 Inhibitor)” is a massive-volume, premium export to endocrinology centers, primary care networks, retail pharmacy distributors, and government health ministries in LATAM, the Middle East, Africa, and Southeast Asia, serving as a highly tolerable, weight-neutral intervention for Type 2 Diabetes Mellitus.

Product Overview

This formulation contains Vildagliptin, a highly selective, reversible inhibitor of the dipeptidyl peptidase-4 (DPP-4) enzyme, representing a massive leap forward in the physiological management of blood sugar.

The “Incretin Protector & Alpha-Cell Suppressor” Specialist:

• Mechanism (DPP-4 Inhibition): When a person eats, the gut naturally releases “incretin” hormones (like GLP-1 and GIP) that tell the pancreas to release insulin. However, an enzyme called DPP-4 destroys these hormones within minutes. Vildagliptin aggressively binds to and blocks the DPP-4 enzyme. This allows the patient’s natural incretin hormones to remain active in the bloodstream much longer, drastically amplifying the body’s natural insulin response to a meal.
• Glucose-Dependent Safety (No Hypoglycemia): Unlike older drugs (like Sulfonylureas) that blindly whip the pancreas into releasing insulin even when blood sugar is low, Vildagliptin is “glucose-dependent.” It only enhances insulin secretion when blood glucose is actually elevated. Once blood sugar returns to normal, the insulin stimulation stops, virtually eliminating the risk of dangerous hypoglycemic shock.
• Glucagon Suppression: In Type 2 Diabetics, the liver inappropriately dumps glucose into the blood because of excess glucagon. The preserved GLP-1 actively suppresses the pancreatic alpha-cells from releasing glucagon, shutting down this unwanted hepatic glucose production.

Product Composition & Strength

We supply this product as a Precision-Blended Uncoated or Film-Coated Tablet, packed strictly in high-barrier Alu-Alu blister strips to guarantee absolute protection from moisture and environmental degradation.

*Pack Sizes: 10×10 or 10×15 Alu-Alu Blisters (Optimized for 30-day chronic diabetic dispensing regimens).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers, Endocrinology Distributors, and Diabetic Clinics.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Dehumidified Encapsulation Suites: To prevent moisture absorption during the manufacturing phase, the blending and compression of Vildagliptin are performed under intense environmental controls. This ensures perfect powder flow and long-term stability of the active pharmaceutical ingredient.
• Dissolution Integrity: Vildagliptin relies on rapid systemic absorption to successfully block the DPP-4 enzyme before post-prandial incretins are destroyed. Rigorous HPLC dissolution profiling guarantees rapid gastric release to flood the bloodstream efficiently.

Therapeutic Indications (Human Use)

Indicated for the comprehensive management of complex metabolic disorders:

• Type 2 Diabetes Mellitus (T2DM): Indicated as an adjunct to diet and exercise to improve glycemic control. It is heavily utilized as dual therapy in combination with Metformin, a Sulfonylurea, or a Thiazolidinedione when diet, exercise, and a single agent do not result in adequate glycemic control.

Dosage & Administration

Recommended Dosage (Strictly as per Endocrinologist/Physician):

• Standard Adult Dosing: When used as monotherapy, or in combination with Metformin or a Thiazolidinedione, the recommended dose is 50 mg twice daily (100 mg total daily dose), typically administered once in the morning and once in the evening.
• Combination with Sulfonylureas: When used in combination with a sulfonylurea (like Glimepiride), the dose is often reduced to 50 mg once daily in the morning to minimize the risk of hypoglycemia driven by the sulfonylurea.
• Administration: Can be taken with or without food.

Safety Warnings (CRITICAL):

• Hepatic Monitoring (Hepatic Toxicity): Rare but severe cases of hepatic dysfunction (including fatal hepatitis) have been reported with Vildagliptin. It is strictly required to perform Liver Function Tests (LFTs) before initiating therapy, and to monitor them at three-month intervals during the first year of treatment. The drug must be discontinued if AST or ALT levels persistently exceed 3x the upper limit of normal.
• Acute Pancreatitis: All DPP-4 inhibitors carry a risk of inducing acute pancreatitis. Patients must be counseled on the hallmark symptom: severe, persistent, radiating abdominal pain. If pancreatitis is suspected, Vildagliptin must be discontinued immediately.
• Heart Failure: While Vildagliptin is generally cardiovascularly safe, clinical data suggests caution when prescribing DPP-4 inhibitors to patients with pre-existing severe congestive heart failure (NYHA class III-IV).

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Endocrinology Formulations, allowing brands to launch high-quality generic medicines under their essential label. Whether you are looking for a reliable Retail Pharmacy Supplier for diabetic care programs in Southeast Asia or a B2B Pharma Marketplace partner for the Middle East, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.