Healthy Inc > Products > Tretiva

Tretiva (Isotretinoin Capsules) 10 mg / 20 mg

Healthy Inc is a specialized global supplier and exporter of advanced dermatology, corrective skin care, and aesthetic therapeutics. We provide ultra-high-purity, kinetically stable Isotretinoin Softgels, manufactured in WHO–GMP certified, high-containment pharmaceutical facilities. This “First-Generation Retinoid” is a high-value strategic export to dermatology clinics, specialized pharmacies, and international B2B distributors, serving as the globally preferred intervention for severe acne that has failed to respond to standard antibiotics and topical therapies.

Product Overview

This formulation operates as a “Genetic Skin Reset.” It ensures patient safety by targeting all four primary physical causes of acne simultaneously.

  • Mechanism 1 (Sebum Suppression): Isotretinoin physically shrinks the Sebaceous Glands by up to 90%. This chemically reduces the oil production that feeds acne-causing bacteria.

  • Mechanism 2 (Follicular Desquamation): It physically prevents the clogging of pores by chemically normalizing the shedding of dead skin cells (Keratinization), physically stopping the formation of comedones.

  • Mechanism 3 (Bacterial Inhibition): By eliminating the oily environment, it physically and chemically inhibits the growth of Cutibacterium acnes without being an antibiotic itself.

  • Mechanism 4 (Anti-Inflammatory): It physically reduces the redness and swelling associated with deep cystic nodules, chemically preventing long-term scarring.

Product Composition & Strengths

We supply this product as Liquid-Filled Soft Gelatin Capsules, optimized for maximum systemic absorption.

Active IngredientStrength (per Softgel)Primary Clinical Target
Isotretinoin IP/BP/USP10 mgStandard Starting Dose: For mild-to-moderate systemic treatment.
Isotretinoin IP/BP/USP20 mgTherapeutic Dose: For severe, cystic, or conglobate acne.
ExcipientsSoybean Oil / BeeswaxThe Vehicle: Ensures lipid-solubility for better absorption.

Technical & Logistics Specifications

  • HS Code: 3004.90.99 (Medicaments acting on the skin / Others)

  • CAS Number: 4759-48-2 (Isotretinoin)

  • Dosage Form: Soft Gelatin Capsule (Softgel)

  • Packaging: 10 Capsules per Blister (Alu-Alu or opaque PVC/PVDC to protect from light). Our specialized packaging ensures 24-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

  • High-Potency Containment: Isotretinoin is a highly sensitive molecule. Our manufacturing process utilizes Closed-Loop Containment Systems, physically protecting the drug from oxidation and light while chemically ensuring 100% dosage accuracy.

  • Lipid-Matrix Stability: Retinoids are physically unstable in water. We utilize a Dehydrated Oil-Based Matrix, physically ensuring the softgel remains potent throughout its shelf life.

  • Bioavailability Assurance: We utilize Precision Particle Micronization, physically ensuring the active drug is small enough to be chemically absorbed efficiently by the gut—a critical factor for clinical success.

Primary Indications

  • Dermatology: Treatment of Severe Cystic Acne and Acne Conglobate.

  • Aesthetics: Management of acne that is physically prone to causing permanent Pitting and Scarring.

  • Specialist Use: Management of resistant Gram-negative folliculitis and severe rosacea.

Usage Instructions

  • Administration: Swallow the softgel physically whole with a full glass of water.

  • Dietary Note: It is physically critical to take Tretiva with a high-fat meal. Isotretinoin is lipid-soluble; taking it on an empty stomach chemically reduces absorption by 50%.

  • Duration: A typical course physically lasts 16 to 24 weeks.

  • Sun Safety: The skin will physically become highly sensitive to UV. Patients must chemically protect themselves with high-SPF sunscreen.

Safety Warning: CRITICAL TERATOGENIC WARNING: Tretiva must NEVER be used during pregnancy. It physically causes Severe Birth Defects. Female patients must physically use two forms of contraception and provide a negative pregnancy test before each refill. Lipid Note: Monitor blood triglycerides and liver enzymes chemically throughout the course. Contraindication: Do not use in patients with hepatic insufficiency, hypervitaminosis A, or known hypersensitivity to isotretinoin or soy.

Global Export & Contract Manufacturing

Healthy Inc is a premier Dermatological and High-Potency Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume Isotretinoin softgels. Whether you are a Premium Derma Brand in the CIS or a B2B Pharma Marketplace partner in Africa or SE Asia, we ensure secure, WHO-GMP compliant delivery

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