Theophylline & Etophylline Oral Syrup (Deriphylline Generic)
Healthy Inc is a specialized global supplier and exporter of advanced respiratory, pediatric, and internal health therapeutics. We provide ultra-high-purity, kinetically stable Theophylline & Etophylline Syrup, manufactured in WHO–GMP certified, high-precision liquid manufacturing facilities. This “Methylxanthine Bronchodilator” combination is a massive-volume strategic export to retail pharmacies, respiratory clinics, and government health ministries, serving as the globally preferred intervention for the maintenance of asthma, chronic bronchitis, and emphysema.
Product Overview
This formulation operates as a “Dual-Action Bronchial Relaxant.” It physically targets the enzymes and receptors in the lungs to maintain open airways over extended periods.
Mechanism 1 (Phosphodiesterase Inhibition): Theophylline physically inhibits the PDE enzyme, which chemically increases the levels of cAMP in the cells. This leads to a physical relaxation of the smooth muscles in the bronchial tubes.
Mechanism 2 (Diaphragmatic Strengthening): It physically increases the strength of the Diaphragm (the primary breathing muscle), making it easier for patients with chronic lung disease to move air.
Mechanism 3 (Etophylline Synergy): Etophylline is a derivative of theophylline that is physically more water-soluble. By combining them, we ensure a faster onset of action and superior bioavailability in a stable liquid form.
Product Composition & Strength
We supply this product as a Sterile, Clear, Alcohol-Free Syrup, optimized for high stability and patient compliance.
| Active Ingredient | Strength (per 5 ml) | Primary Clinical Function |
| Etophylline IP/BP | 47 mg – 100 mg | The Soluble Bronchodilator: Rapid airway relaxation. |
| Theophylline IP/BP | 14 mg – 30 mg | The Sustained Bronchodilator: Long-term airway maintenance. |
| Excipients | Sorbitol / Glycerin | The Vehicle: Ensures chemical stability and taste. |
| Flavoring | Orange / Mixed Fruit / Pineapple | The Palatable Base: Essential for child and adult compliance. |
Technical & Logistics Specifications
HS Code: 3004.41.00 (Medicaments containing Ephedrine/Theophylline/Pseudoephedrine)
CAS Numbers: 58-55-9 (Theophylline) / 519-37-9 (Etophylline)
Dosage Form: Oral Liquid (Syrup)
Packaging: 60 ml / 100 ml / 200 ml PET or Amber Glass Bottles. Our specialized packaging ensures 36-month stability in Zone IVb tropical climates.
Manufacturing Authority & Compliance
Precision Homogenization: Theophylline has a narrow therapeutic window. Our manufacturing process utilizes High-Shear Homogenization to ensure an exact dose is physically uniform in every 5 ml, preventing toxic spikes or sub-therapeutic doses.
Aseptic Liquid Filling: We utilize Automated Liquid Filling Lines with 100% microbial testing to ensure total safety for patients with chronic respiratory conditions.
Sugar-Free Options: We offer specialized Sugar-Free formulations, making the product physically safe for elderly diabetic patients who suffer from COPD.
Primary Indications
Respiratory: Maintenance treatment of Bronchial Asthma and Chronic Bronchitis.
COPD: Long-term management of Emphysema and obstructive airway diseases.
Pediatrics: Management of “Nighttime Asthma” where long-acting bronchodilation is physically required.
Geriatrics: Relief of breathlessness in elderly patients with stable chronic lung conditions.
Dosage & Administration
Adults: Typically 10 ml to 20 ml taken 2 to 3 times daily.
Children (6-12 years): Typically 5 ml to 10 ml taken 2 to 3 times daily.
Administration: For maximum safety and to reduce gastric upset, it should physically be taken after food.
Hydration Note: It is physically best to maintain good hydration to support the clearance of the medicine.
Safety Warning: For Oral Use Only. Narrow Therapeutic Index: Physicians should physically monitor patients for signs of toxicity (nausea, restlessness, or heart palpitations). Interaction Note: Theophylline physically interacts with many drugs (e.g., Ciprofloxacin, Erythromycin); consult a doctor for concurrent therapy. Contraindication: Do not use in patients with active peptic ulcers, acute myocardial infarction, or known hypersensitivity to xanthine derivatives.
Global Export & Contract Manufacturing
Healthy Inc is a premier Respiratory and Pediatric Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume bronchial maintenance syrups. Whether you are a National Respiratory Program in the CIS or a B2B Pharma Marketplace partner in Africa or SE Asia, we ensure secure, WHO-GMP compliant delivery.