Sumatriptan Tablets (25 mg / 50 mg / 100 mg)

Healthy Inc is a specialized global supplier and exporter of advanced neurology, central nervous system (CNS), and acute pain therapeutics. We provide ultra-high-purity, fast-acting Sumatriptan Succinate Film-Coated Tablets (25 mg / 50 mg / 100 mg), manufactured in WHO–GMP certified, high-precision oral solid dosage facilities. This “Selective 5-HT1 Receptor Agonist” is a massive-volume, premium export to neurology clinics, specialized headache centers, primary care networks, and government health ministries in LATAM, the Middle East, Africa, and Southeast Asia, serving as the globally mandated, definitive abortive intervention for acute migraine attacks.

Product Overview

This formulation contains Sumatriptan (as Sumatriptan Succinate), a revolutionary “triptan” molecule that fundamentally changed migraine treatment. Unlike standard painkillers, it does not just mask the pain; it actively reverses the physiological processes causing the migraine.

The “Acute Migraine Abortive” Specialist:

• Mechanism 1 (Cranial Vasoconstriction): During a migraine, blood vessels in the brain dangerously dilate (widen). Sumatriptan acts as a highly selective agonist at the 5-HT1B and 5-HT1D serotonin receptors located on these specific intracranial blood vessels. By stimulating these receptors, it forces the swollen blood vessels to constrict back to their normal size, relieving the throbbing pressure.
• Mechanism 2 (Trigeminal Nerve Inhibition): Simultaneously, Sumatriptan binds to receptors on the trigeminal nerve (the primary pain pathway in the head). It physically blocks the nerve from releasing pro-inflammatory neuropeptides (like CGRP), rapidly shutting down the inflammatory pain cycle, nausea, and severe sensitivity to light and sound (photophobia and phonophobia).
• The “Abortive” Distinction: It is crucial for clinical networks to understand that Sumatriptan is strictly an abortive medication, not a preventative one. It is used to kill a migraine that has already started, but it will not prevent future migraines from occurring.

Product Composition & Strength

We supply this product as a Precision-Blended Film-Coated Tablet, packed exclusively in highly secure, child-resistant Alu-Alu or high-density Alu-PVC blister strips to ensure the stability of the active ingredient and prevent accidental pediatric ingestion.

*Pack Sizes: 1×2, 1×4, or 1×6 Unit-Dose Blisters (Optimized specifically to enforce strict dispensing limits and prevent medication overuse).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers, Neurology Distributors, and Retail Pharmacy Chains.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Rapid Disintegration Engineering: When a migraine strikes, the gastrointestinal tract often shuts down (gastric stasis), delaying the absorption of oral drugs. Our Sumatriptan tablets are specifically engineered with advanced superdisintegrants to ensure they break down almost instantly upon reaching the stomach, maximizing rapid systemic absorption to provide clinical relief within 30 to 60 minutes.

Therapeutic Indications (Human Use)

Indicated for the targeted, acute management of severe neurological pain:

• Acute Migraine: Acute treatment of migraine attacks with or without aura in adults.
• CRITICAL LIMITATION: It is strictly NOT indicated for the prophylactic (preventative) therapy of migraine or for the management of hemiplegic or basilar migraine.

Dosage & Administration

Recommended Dosage (Strictly as per Neurologist Guidelines):

• Standard Adult Dosing: 50 mg or 100 mg taken orally at the very first sign of a migraine headache.
• The “2-Hour” Re-Dosing Rule: If the migraine symptoms return after an initial positive response, a second tablet may be taken, but only if at least 2 hours have passed since the first dose.
• Maximum Limits: Do not exceed 200 mg in any 24-hour period.
• Administration: Swallow the tablet whole with water. Can be taken with or without food.

Safety Warnings (CRITICAL Regulatory & Clinical Data):

• BLACK BOX EQUIVALENT (Cardiovascular/Vasospasm Risk): Because Sumatriptan constricts blood vessels, it can cause severe, sometimes fatal, coronary artery vasospasm, myocardial infarction (heart attack), or stroke. It is STRICTLY CONTRAINDICATED in patients with a history of ischemic heart disease, angina pectoris, previous heart attacks, strokes, or uncontrolled hypertension.
• Serotonin Syndrome: Sumatriptan is a potent serotonergic agent. Co-administration with SSRI or SNRI antidepressants (like Fluoxetine or Duloxetine) can trigger potentially fatal Serotonin Syndrome, characterized by severe agitation, hallucinations, rapid heart rate, and fever.
• Ergotamine Interaction (24-Hour Rule): It must NEVER be used within 24 hours of taking another triptan or any ergotamine-containing medication (like Cafergot), as this will cause catastrophic, prolonged vasospasm.
• Medication Overuse Headache (MOH): Using acute migraine drugs (like Sumatriptan) for 10 or more days per month can trap the patient in a cycle of severe “rebound” headaches. Patients using it this frequently must be transitioned to prophylactic therapy.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Retail Pharmacy Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Neurological Formulations, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Pharmacy Chain Supplier in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.