Racecadotril Tablets / Capsules (100 mg)

Healthy Inc is a specialized global supplier and exporter of advanced gastroenterological, anti-infective, and acute-care therapeutics. We provide ultra-high-purity, kinetically optimized Racecadotril Film-Coated Tablets / Hard Capsules (100 mg), manufactured in WHO–GMP certified, high-precision oral solid dosage facilities. This “Intestinal Enkephalinase Inhibitor” is a highly lucrative, premium export to gastroenterology clinics, infectious disease NGOs, retail pharmacy networks, and government health ministries in LATAM, the CIS, Africa, and Southeast Asia, serving as the globally mandated, pure anti-secretory intervention for the rapid, safe treatment of acute secretory diarrhea.

Product Overview

This highly advanced formulation contains Racecadotril, a prodrug that acts as a highly targeted “leak-stopper” in the gut, fundamentally changing the clinical approach to acute, infectious, and secretory diarrhea.

The “Pure Anti-Secretory & Toxin-Flushing” Specialist:

• Mechanism 1 (The Enkephalinase Blockade): The human gut naturally produces peptides called enkephalins that absorb water and keep the intestines dry. However, an enzyme called enkephalinase constantly destroys them. When a patient gets acute diarrhea (often from a bacterial or viral toxin), the gut hyper-secretes massive amounts of water. Racecadotril aggressively inhibits the enkephalinase enzyme. This allows the body’s natural enkephalins to survive and massively reduce the hypersecretion of water and electrolytes into the gut lumen.
• Mechanism 2 (The Loperamide-Sparing Advantage – CRITICAL): Standard anti-diarrheals (like Loperamide) work by paralyzing the smooth muscle of the gut (stopping peristalsis). If a patient has bacterial diarrhea, paralyzing the gut traps the toxic bacteria inside their body, which can lead to severe fever, sepsis, or toxic megacolon. Racecadotril is purely anti-secretory. It does absolutely nothing to slow down bowel motility. It simply stops the fluid leak while allowing the body to safely and naturally flush the pathogen out.
• Zero Rebound Constipation: Because it does not paralyze the bowel, Racecadotril causes virtually zero rebound constipation or painful abdominal bloating, making it the preferred, highly tolerable prescription for acute outpatient care.

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers, OTC Distributors, and Hospital Procurement Boards.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Rapid Prodrug Dissolution Engineering: Racecadotril is a prodrug that must be rapidly converted into its active metabolite (Thiorphan) in the body to stop severe diarrhea quickly. Our facilities utilize advanced high-shear granulation and superdisintegrants to ensure the tablet or capsule rapidly shatters in the stomach, guaranteeing a highly predictable, rapid onset of clinical action within the first few hours of the acute episode.

Therapeutic Indications (Human Use)

Indicated for the targeted, anti-secretory management of acute gastrointestinal fluid loss:

• Acute Diarrhea: Symptomatic treatment of acute diarrhea in adults when causal treatment is not possible. If causal treatment is possible, Racecadotril can be administered as a complementary therapy.

Dosage & Administration

Recommended Dosage (Strictly as per Physician Guidelines):

• Standard Adult Dosing: Initially, one 100 mg tablet/capsule at any time of day. Following this, one 100 mg tablet/capsule taken three times daily (TID).
• Administration (THE MEALTIME RULE): To maximize clinical efficacy, the doses should preferably be taken immediately before main meals. Tablets must be swallowed whole with a glass of water.
• Duration of Therapy: Treatment should be continued until two normal stools are recorded. Treatment must not exceed 7 days.

Safety Warnings (CRITICAL Regulatory & Clinical Data):

• The ORS Mandate (CRITICAL): Racecadotril stops the hypersecretion of fluids, but it does not rehydrate the patient. The administration of this drug must always be accompanied by abundant fluid intake or standard Oral Rehydration Salts (ORS) to prevent fatal dehydration.
• Dysentery Warning: Even though it is safer than Loperamide, patients experiencing acute dysentery (characterized by high fever and visible blood or pus in the stool) should undergo medical evaluation before relying solely on symptomatic anti-diarrheal agents, as systemic antibiotics may be required.
• Cutaneous Reactions: Severe skin reactions have been reported rarely with Racecadotril. Treatment must be permanently discontinued at the first sign of a severe skin rash or mucosal lesions.
• ACE Inhibitor Interaction: Concomitant use with ACE inhibitors (like Ramipril or Lisinopril) may slightly increase the risk of angioedema.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Retail Pharmacy Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Gastroenterological Formulations, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Government Tender Supplier for acute GI clinics in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.