Pregabalin Capsules / Sustained-Release Tablets (75 mg / 150 mg / 300 mg)

Healthy Inc is a specialized global supplier and exporter of advanced neurology, neuropathic pain, and central nervous system (CNS) therapeutics. We provide ultra-high-purity, kinetically precise Pregabalin Hard Gelatin Capsules & Sustained-Release (SR) Tablets, manufactured in WHO–GMP certified, high-security controlled-substance oral solid dosage facilities. This “Alpha-2-Delta Ligand Neuromodulator” is a massive-volume, highly lucrative export to neurology centers, diabetic care clinics, retail pharmacy networks, and government health ministries in LATAM, the CIS, Africa, and Southeast Asia, serving as the globally mandated, first-line intervention for severe Neuropathic Pain, Fibromyalgia, and Generalized Anxiety Disorder (GAD).

Product Overview

This highly advanced formulation contains Pregabalin, a potent gabapentinoid that fundamentally alters how the brain and spinal cord process pain signals, quieting hyperactive nerves without relying on addictive opioid pathways.

The “Neuropathic Shield & Nerve Calmer” Specialist:

• Mechanism 1 (The Calcium Channel Blockade): In patients with severe nerve damage (from diabetes, shingles, or spinal cord injury), the nerves become dangerously hyperactive, firing continuous, agonizing “shock-like” pain signals to the brain. Pregabalin directly binds to the alpha-2-delta subunit of voltage-gated calcium channels in the CNS. By doing so, it physically blocks the influx of calcium into the nerve terminals, violently shutting down the release of excitatory pain neurotransmitters (like glutamate and substance P).
• Mechanism 2 (The Diabetic & Fibromyalgia Standard): Unlike standard pain, neuropathic pain and fibromyalgia involve a completely rewired central nervous system. Pregabalin “turns down the volume” on this hypersensitivity, providing profound relief for patients whose lives are paralyzed by constant burning, tingling, or widespread musculoskeletal pain.
• Mechanism 3 (Adjunctive Seizure & Anxiety Control): Beyond pain, its ability to calm hyper-excited neural networks makes it an elite add-on therapy for controlling partial-onset epileptic seizures. Furthermore, in many global regions (like the EU), it is a heavily prescribed, rapid-acting treatment for Generalized Anxiety Disorder (GAD).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers, Neurology Distributors, and Hospital Procurement Boards.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Strict Regulatory Containment & High-Throughput Encapsulation: Because Pregabalin holds controlled-substance status in many jurisdictions, our facilities operate under absolute, audited security protocols to prevent API diversion. We utilize advanced, high-speed automated encapsulation machinery capable of fulfilling massive government and retail tenders while maintaining flawless, zero-variance content uniformity across millions of units.

Therapeutic Indications (Human Use)

Indicated for the targeted management of severe neuropathic and neurological dysfunctions:

• Neuropathic Pain: Management of neuropathic pain associated with Diabetic Peripheral Neuropathy (DPN), Post-Herpetic Neuralgia (PHN), and spinal cord injury.
• Fibromyalgia: Management of widespread musculoskeletal pain and fatigue associated with fibromyalgia.
• Epilepsy: Adjunctive therapy for adult patients with partial-onset seizures.
• Generalized Anxiety Disorder (Off-Label / Regional Standard): Treatment of GAD in adults where standard SSRIs are ineffective or poorly tolerated.

Dosage & Administration

Recommended Dosage (Strictly as per Neurologist Guidelines):

• Diabetic Neuropathy / Post-Herpetic Neuralgia: Begin at 75 mg two times a day (150 mg/day). May be increased to 300 mg/day within 1 week based on efficacy and tolerability. Maximum recommended dose is 600 mg/day.
• Administration (THE TITRATION RULE): Pregabalin must be slowly titrated up to the therapeutic dose to prevent severe dizziness and extreme sleepiness (somnolence). It can be taken with or without food.
• Discontinuation: It must NEVER be stopped abruptly. Sudden withdrawal can cause severe insomnia, nausea, headaches, diarrhea, and potentially trigger rebound epileptic seizures. It must be tapered off slowly over a minimum of 1 week.

Safety Warnings (CRITICAL Regulatory & Clinical Data):

• Abuse, Misuse, and Addiction Potential: Pregabalin produces euphoric effects at high doses and is increasingly abused, particularly in combination with opioids. Physicians must evaluate patients for a history of drug abuse and observe them for signs of misuse.
• Respiratory Depression: There is a severe risk of fatal respiratory depression when Pregabalin is used concomitantly with opioid analgesics or other CNS depressants, particularly in the elderly or those with underlying respiratory impairment.
• Weight Gain & Peripheral Edema: Pregabalin frequently causes significant weight gain and fluid retention (swelling of the hands and feet). It must be used with caution in patients with heart failure (NYHA Class III or IV).
• Suicidal Behavior and Ideation: Like all antiepileptic drugs (AEDs), it increases the risk of suicidal thoughts or behavior. Patients must be monitored for the emergence or worsening of depression or unusual changes in mood.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving international Pharma Traders, Wholesalers, and Retail Pharmacy Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Neurological and Pain Management Formulations. Whether you are looking for a reliable Government Tender Supplier for diabetes clinics in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely, secure delivery of heavily regulated, WHO-GMP certified products.