Phenobarbital Tablets (15 mg / 30 mg / 60 mg / 100 mg)

Healthy Inc is a specialized global supplier of essential neurotropic and antiepileptic therapies. We provide premium Phenobarbital Tablets, manufactured in WHO–GMP certified controlled-substance units. As a WHO-listed Essential Medicine for seizure control, this product is a primary export for neurology clinics, state mental health programs, and Ministry of Health (MOH) tenders in Southeast Asia, Africa, and the CIS region.

Product Overview

Phenobarbital is a long-acting barbiturate with potent anticonvulsant properties. It is specifically engineered to provide sustained elevation of the seizure threshold, making it the most widely used anticonvulsant globally for the long-term management of generalized and partial seizures.

The “Gold Standard” Anticonvulsant:

• Mechanism of Action: Phenobarbital acts as a non-selective Central Nervous System (CNS) depressant. It primarily works by binding to the GABA-A receptor, prolonging the opening of chloride ion channels. This action hyperpolarizes neurons, increasing synaptic inhibition and suppressing the spread of seizure activity.
• Pharmacokinetic Stability: With an exceptionally long half-life (~50–120 hours), Phenobarbital provides extremely stable plasma concentrations. This makes it highly “forgiving” regarding missed doses, which is a critical factor in patient compliance and seizure prevention.
• Broad Spectrum Utility: Beyond epilepsy, it is utilized for its sedative and hypnotic properties in preoperative settings and as a specialized treatment for neonatal jaundice by inducing hepatic enzymes.

Technical & Manufacturing Specifications

Formulated for precise dosing and high molecular stability.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from high-security, specialized units.

• Regulatory Rigor: As a controlled substance, our manufacturing is subject to strict quota monitoring and security protocols. We handle all Export Permits and International Import Certificates (IIC) required for cross-border transit.
• Content Uniformity: For low-dose pediatric tablets (15 mg), we utilize validated high-shear granulation to ensure perfect distribution of the API, preventing dose-related toxicity or sub-therapeutic failure.
• Stability Excellence: Phenobarbital is remarkably stable. Our tablets are validated for Climatic Zone IVb, ensuring they remain potent for over 3 years in extreme tropical heat and humidity.

Therapeutic Indications & Clinical Symptoms

• Epilepsy: Management of generalized tonic-clonic seizures and partial seizures.
• Status Epilepticus: Maintenance therapy following acute control of prolonged seizures.
• Sedation: Short-term relief of anxiety and tension.
• Neonatal Hyperbilirubinemia: Adjunctive treatment to reduce bilirubin levels via hepatic enzyme induction.

Dosage & Administration

• Dosing: Usually ranges from 60 mg to 200 mg daily for adults, often taken at bedtime due to its sedative effect.
• Monitoring: Periodic Therapeutic Drug Monitoring (TDM) is recommended to maintain serum levels within the 15–40 mcg/mL range.
• Abrupt Withdrawal Warning: Treatment must not be stopped suddenly; gradual tapering is mandatory to avoid status epilepticus or withdrawal syndrome.

Global Export & Contract Manufacturing Services

Healthy Inc is a verified Pharmaceutical Exporter in Mumbai, catering to National Health Services and International Aid Agencies. We offer Third Party Manufacturing for Phenobarbital with full CTD Dossier and COPP support. Our logistics network handles Controlled Substance shipping to Vietnam, Nigeria, Kenya, and the Philippines, providing WHO-GMP quality at competitive B2B prices.

Commercial Inquiries

WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in