Ornidazole Film-Coated Tablets (500 mg)

Healthy Inc is a specialized global supplier and exporter of advanced anti-infective, antiprotozoal, and gastroenterological therapeutics. We provide ultra-high-purity, kinetically optimized Ornidazole Film-Coated Tablets (500 mg), manufactured in WHO–GMP certified, high-precision oral solid dosage facilities. This “Next-Generation 5-Nitroimidazole” is a massive-volume, highly lucrative export to gastroenterology clinics, gynecology networks, surgical centers, and government health ministries in LATAM, the CIS, Africa, and Southeast Asia, serving as the globally mandated, high-compliance intervention for severe Amoebiasis, Giardiasis, Trichomoniasis, and aggressive anaerobic bacterial infections.

Product Overview

This highly advanced formulation contains Ornidazole, a potent, long-acting synthetic antimicrobial agent that safely penetrates deep into infected tissues before deploying a lethal, target-specific attack strictly against anaerobic organisms and protozoa.

The “Amoebicidal & Anaerobic Shield” Specialist:

• Mechanism 1 (The Intracellular DNA Shredder): Ornidazole is a prodrug that is only activated in environments completely devoid of oxygen. When it enters an anaerobic bacterium or a protozoan parasite, the organism’s own enzymes chemically reduce the Ornidazole molecule. This reduction creates highly reactive, toxic intermediates that violently attack the organism’s DNA, shredding its genetic code and causing rapid, irreversible cell death.
• Mechanism 2 (The Metronidazole Upgrade – CRITICAL): Metronidazole (the older standard) is cleared from the body very quickly (an 8-hour half-life), requiring strict, high-burden dosing regimens. Ornidazole possesses an extended 13-hour half-life, providing profound, sustained tissue concentrations that allow for convenient twice-daily (or sometimes single-dose) regimens. Furthermore, it causes significantly less nausea and avoids the severe “metallic taste” that causes patients to abandon Metronidazole.
• The Gynecological & Surgical Defender: Beyond gut infections, Ornidazole achieves massive concentrations in vaginal and pelvic tissues, making it the gold standard for Trichomoniasis and Bacterial Vaginosis. It is also heavily stockpiled by surgical wards for the prophylaxis of deep-tissue infections following complex abdominal or colorectal surgeries.

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers, Infectious Disease Distributors, and Hospital Procurement Boards.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Intensive Taste-Masking & Film-Coating Engineering: The entire nitroimidazole class is plagued by a highly aversive, bitter taste that triggers immediate nausea upon contact with the tongue. Our facilities utilize advanced fluid-bed or high-shear granulation followed by a high-density Hypromellose (HPMC) polymer film-coating process. This completely locks the API inside a smooth, tasteless barrier that only dissolves once it safely reaches the stomach, guaranteeing that even highly sensitive patients can complete their full course of therapy.

Therapeutic Indications (Human Use)

Indicated for the targeted eradication of susceptible anaerobic and protozoal pathogens:

• Amoebiasis: Treatment of severe intestinal amoebiasis (amoebic dysentery) and extra-intestinal amoebiasis (including amoebic liver abscess).
• Trichomoniasis: Treatment of genitourinary infections in both men and women caused by Trichomonas vaginalis.
• Giardiasis: Eradication of Giardia lamblia in the small intestine.
• Anaerobic Bacterial Infections: Treatment of septicemia, meningitis, peritonitis, postoperative wound infections, and severe dental infections caused by susceptible anaerobes (like Bacteroides fragilis or Clostridium species).

Dosage & Administration

Recommended Dosage (Strictly as per Physician Guidelines):

• Amoebic Dysentery: 1.5 grams once daily for 3 days, or 500 mg twice daily for 5 to 10 days.
• Trichomoniasis: A single 1.5-gram dose, or 500 mg twice daily for 5 days. (Sexual partners must be treated simultaneously to prevent re-infection).
• Administration (THE MEALTIME RULE): To minimize the risk of gastric irritation, tablets must always be taken after meals with a full glass of water. Tablets must be swallowed whole to preserve the taste-masking film coat.

Safety Warnings (CRITICAL Regulatory & Clinical Data):

• Central Nervous System (CNS) Toxicity: High doses or prolonged use can cause severe neurological disturbances, including dizziness, severe vertigo, tremors, rigidity, and in rare cases, peripheral neuropathy or epileptic seizures. Discontinue immediately if severe neurological symptoms manifest.
• Alcohol Interaction (Disulfiram-Like Reaction): While Ornidazole is generally considered less reactive with alcohol than Metronidazole, patients should still be strictly warned to avoid all alcohol consumption during therapy and for at least 3 days after the last dose to prevent violent nausea, vomiting, flushing, and tachycardia.
• Hepatic Impairment: Because Ornidazole is extensively metabolized by the liver, the dosing interval must be doubled (e.g., from every 12 hours to every 24 hours) in patients with severe hepatic cirrhosis to prevent toxic accumulation.
• Pregnancy Warning: Like all nitroimidazoles, it crosses the placental barrier and should be strictly avoided during the first trimester of pregnancy unless absolutely clinically necessary.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving international Pharma Traders, Wholesalers, and NGO Health Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Anti-Infective and Antiprotozoal Formulations. Whether you are looking for a reliable Government Tender Supplier for dysentery outbreak control in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely, secure delivery of highly stable, WHO-GMP certified products.