Naproxen Sodium Film-Coated Tablets (275 mg / 550 mg)

Healthy Inc is a specialized global supplier and exporter of advanced acute analgesic, orthopedic, and rapid-acting anti-inflammatory therapeutics. We provide ultra-high-purity, kinetically optimized Naproxen Sodium Film-Coated Tablets (275 mg / 550 mg), manufactured in WHO–GMP certified, high-precision rapid-dissolution oral solid dosage facilities. This “Rapid-Onset, Long-Acting NSAID” is a massive-volume, highly lucrative export to emergency departments, sports medicine clinics, retail OTC pharmacy networks, and government health ministries in LATAM, the CIS, Africa, and Southeast Asia, serving as the globally mandated, fast-acting intervention for acute migraines, severe primary dysmenorrhea, post-operative dental pain, and sudden musculoskeletal trauma.

Product Overview

This highly advanced formulation utilizes the highly soluble sodium salt of Naproxen, specifically engineered to shatter the delay between swallowing the pill and achieving profound, systemic pain relief, without sacrificing the molecule’s extended 12-hour duration of action.

The “Rapid-Onset & 12-Hour Acute Relief” Specialist:

• Mechanism 1 (The Salt-Accelerated Absorption – CRITICAL): Standard Naproxen is highly insoluble in the acidic stomach, meaning it dissolves and absorbs very slowly. By replacing it with Naproxen Sodium, the molecule instantly dissolves the moment it touches gastric fluid. This slashes the Tmax (time to peak blood concentration) from 2-4 hours down to just 1 hour, violently shutting down the COX-1 and COX-2 enzymes to deliver profound pain relief within 30 minutes of ingestion.
• Mechanism 2 (The Prostaglandin Blockade): Once in the bloodstream, it aggressively penetrates inflamed tissues and the central nervous system, stopping the production of hyper-algesic prostaglandins. This rapidly eliminates acute swelling, drops high fevers, and blocks the transmission of agonizing pain signals to the brain.
• The Migraine & Dysmenorrhea Gold Standard: In conditions like acute migraine attacks or crippling menstrual cramps (primary dysmenorrhea), the pain escalates exponentially. The rapid burst of Naproxen Sodium intercepts the inflammatory cascade before it peaks, making it the undisputed, first-line heavy artillery for young, active patients requiring immediate return to function.

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers, Pain Management Distributors, and Hospital Procurement Boards.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Superdisintegrant & Moisture-Barrier Engineering: Generating a rapid onset of action with a highly hygroscopic API requires elite manufacturing controls. If the tablet absorbs ambient moisture in the factory, it will become soft and fail to dissolve rapidly in the patient’s stomach. Our facilities utilize advanced high-shear dry-blending in strict, humidity-controlled suites (RH < 35%), integrating high-performance superdisintegrants like Croscarmellose Sodium. This is immediately followed by a low-moisture film-coating process, ensuring the tablet remains rock-solid during transport but shatters instantly upon ingestion.

Therapeutic Indications (Human Use)

Indicated for the rapid, comprehensive management of severe acute pain and inflammation:

• Acute Migraine Attacks: Rapid abortion of migraine headaches, with or without aura.
• Primary Dysmenorrhea: Fast, sustained relief of severe menstrual cramping and pelvic pain.
• Acute Musculoskeletal Trauma: Management of sudden sprains, strains, and sports injuries.
• Post-Operative & Dental Pain: Acute analgesia following dental extractions or minor surgical procedures.
• Acute Gout: Rapid suppression of intense, crystal-induced joint inflammation.

Dosage & Administration

Recommended Dosage (Strictly as per Physician Guidelines):

• Acute Pain / Dysmenorrhea / Migraine: Typically initiated with a heavy “loading dose” of 550 mg, followed by 275 mg every 6 to 8 hours as needed. Total daily dose should not exceed 1375 mg.
• Administration (THE FULL GLASS RULE): To prevent the rapidly dissolving salt from adhering to the esophagus and causing acute severe heartburn, tablets MUST be taken with a full 8 oz glass of water, preferably with food or milk to minimize gastric irritation.

Safety Warnings (CRITICAL Regulatory & Clinical Data):

• BLACK BOX WARNING (Cardiovascular & GI Risk): Like all NSAIDs, it may cause an increased risk of serious cardiovascular thrombotic events (myocardial infarction and stroke) and severe gastrointestinal adverse events (bleeding, ulceration, and perforation of the stomach).
• The Sodium Load Warning (Cardiac/Renal Patients): Because this is the Sodium salt form, each 550 mg tablet contains approximately 50 mg of elemental sodium. In patients with severe congestive heart failure, severe hypertension, or those on strict, medically mandated very-low-sodium diets, this hidden sodium load can cause sudden fluid retention and acute cardiac decompensation.
• Renal Impairment: By blocking prostaglandins, it can severely drop renal blood flow, causing acute kidney failure. Use with extreme caution in volume-depleted patients.
• Aspirin-Sensitive Asthma: Strictly contraindicated in patients who have experienced severe asthma, urticaria, or allergic-type reactions after taking Aspirin.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving international Pharma Traders, Wholesalers, and Retail Pharmacy Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Acute Analgesic and Rapid-Release Formulations. Whether you are looking for a reliable Retail OTC Supplier for pharmacy chains in the CIS or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely, secure delivery of highly stable, WHO-GMP certified products.