Metoclopramide Tablets (10 mg)

Healthy Inc is a premier global supplier of high-precision gastrointestinal therapies. We provide premium Metoclopramide Hydrochloride Tablets, manufactured in WHO–GMP certified specialized solid dosage facilities. As a critical agent for the management of gastroparesis and chemotherapy-induced nausea, this product is a vital export for oncology centers, gastroenterology clinics, and Ministry of Health (MOH) tenders in Southeast Asia, Africa, and the CIS region.

Product Overview

Metoclopramide is a potent dopamine receptor antagonist with unique prokinetic properties. It is specifically engineered to stimulate upper gastrointestinal motility without affecting gastric, biliary, or pancreatic secretions, making it indispensable for conditions involving delayed gastric emptying.

The “Motility & Emesis” Specialist:

• Mechanism of Action: Metoclopramide acts by antagonizing D2 dopamine receptors in the Chemoreceptor Trigger Zone (CTZ) of the brain, effectively blocking the nausea signal. Peripherally, it sensitizes tissues to acetylcholine, increasing the tone and amplitude of gastric contractions and relaxing the pyloric sphincter.
• Prokinetic Efficacy: It significantly accelerates gastric emptying and intestinal transit, providing rapid relief for patients suffering from diabetic gastroparesis and symptomatic GERD.
• Antiemetic Versatility: It is highly effective in preventing nausea and vomiting associated with emetogenic cancer chemotherapy, post-operative recovery, and acute migraine attacks.

Technical & Manufacturing Specifications

Formulated for rapid disintegration and absolute content uniformity.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from ISO 9001:2015 certified units.

• Stability Validation: Validated for Zone IVb climates. Our tablets are formulated with specialized stabilizers to prevent the oxidation of the hydrochloride salt, ensuring a 36-month shelf life in tropical export markets.
• High-Precision Blending: Given the 10 mg potency, we utilize validated micronization and geometric dilution to ensure every tablet provides the exact therapeutic dose required to avoid extrapyramidal side effects.
• Photosensitivity Protocols: Metoclopramide is light-sensitive. Our manufacturing utilizes opaque film-coating and UV-protected primary packaging to maintain molecular integrity from factory to patient.

Therapeutic Indications & Clinical Symptoms

• Diabetic Gastroparesis: Relief of symptoms associated with acute and recurrent delayed gastric emptying (nausea, vomiting, persistent fullness).
• Gastroesophageal Reflux Disease (GERD): Short-term therapy for patients who fail to respond to conventional anti-secretory drugs.
• Prevention of Nausea: Prophylaxis of postoperative nausea and vomiting (PONV) and chemotherapy-induced emesis.
• Small Bowel Intubation: To facilitate the passage of tubes into the small intestine for diagnostic procedures.

Dosage & Administration

• Administration: Typically taken 30 minutes before meals and at bedtime.
• Standard Dose: 10 mg up to four times daily. Treatment duration should generally not exceed 12 weeks.
• Safety Note: Black Box Warning: Risk of Tardive Dyskinesia (involuntary muscle movements) with long-term or high-dose use. Avoid use in patients with epilepsy or GI hemorrhage/obstruction.

Global Export & Contract Manufacturing Services

Healthy Inc is a verified Gastrointestinal Drug Exporter in Mumbai, catering to Oncology Clinics and Ministry of Health Tenders. We offer Third Party Manufacturing for Metoclopramide with full CTD Dossier and COPP support. Our logistics network ensures secure transit to Vietnam, Nigeria, Uzbekistan, and the Philippines, providing WHO-GMP quality at competitive B2B prices.