Levocarnitine Injection
Healthy Inc is a specialized global supplier and exporter of metabolic and renal therapeutic agents. We provide high-purity Levocarnitine Injection (1 g / 5 ml), manufactured in WHO–GMP certified sterile facilities. This “Cellular Fuel” specialist is a top export to nephrology centers, dialysis clinics, and government health ministries in Africa, LATAM, and Southeast Asia, serving as the essential treatment for carnitine deficiency in chronic kidney disease (CKD) and rare metabolic disorders.
Product Overview
This formulation contains Levocarnitine (L-Carnitine), a naturally occurring amino acid derivative required for energy metabolism.
The “Mitochondrial Carrier” Specialist:
- Mechanism (The Carnitine Shuttle): Levocarnitine is the only molecule capable of transporting long-chain fatty acids across the inner mitochondrial membrane. Once inside, these fatty acids undergo β-oxidation to produce ATP (energy). Without sufficient Levocarnitine, fatty acids accumulate, leading to muscle weakness and cardiac dysfunction.
- Dialysis Recovery: Patients on long-term hemodialysis often lose carnitine through the dialysate. IV Levocarnitine replenishment helps manage dialysis-related symptoms such as severe muscle cramps, hypotension, and erythropoietin-resistant anemia.
- Cardioprotective Role: It improves the energy supply to the myocardium, making it a supportive therapy in cardiomyopathy and ischemic heart disease.
Product Composition & Strength
We supply this product as a Sterile, Clear, Colorless Solution in glass ampoules or vials.
| Active Ingredient | Strength | Concentration |
|---|---|---|
| Levocarnitine USP/BP | 1 Gram (1000 mg) | 200 mg/ml (in 5 ml Ampoule) |
| Excipients | Water for Injection | pH Adjusted (6.0 – 6.5) |
*Pack Sizes: Tray of 5 Ampoules, 10 Ampoules, or Single Use Vials.
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.90.99 (Medicaments containing other active substances) |
| CAS Number | 541-15-1 |
| Dosage Form | Injection (Liquid Solution) |
| Packaging | Type I Glass Ampoule or Glass Vial. |
| Storage | Store below 25°C. Protect from Light. (Solution is stable but photosensitive). |
| Certificates | WHO-GMP, COPP, Free Sale Certificate |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Stereoisomeric Purity: We guarantee 100% L-isomer (Levocarnitine). The D-isomer is toxic as it competes for carnitine transporters and can cause “D-carnitine deficiency.” Our enzymatic synthesis ensures zero D-isomer contamination.
- Pyrogen-Free Standard: Since this drug is often administered directly into the venous return line of a hemodialysis machine, our manufacturing process undergoes double-stage ultrafiltration to ensure absolute pyrogen-free status.
Therapeutic Indications (Human Use)
Indicated for the treatment of carnitine deficiency:
- Primary Carnitine Deficiency: Genetic metabolic disorders.
- Secondary Carnitine Deficiency: Resulting from End-Stage Renal Disease (ESRD) and chronic hemodialysis.
- Valproate Toxicity: To manage hyperammonemia caused by Valproic Acid overdose.
- Pediatrics: Management of failure to thrive in infants with metabolic errors.
Dosage & Administration
Recommended Dosage (Strictly as per Physician):
- Route: Slow Intravenous (IV) Injection or Infusion.
- Hemodialysis Patients: 10 mg/kg to 20 mg/kg administered as a bolus into the venous return line after each dialysis session.
- Metabolic Crisis: Up to 50 mg/kg to 100 mg/kg daily in divided doses.
- Note: Discard any unused portion immediately after opening as it contains no preservatives.
Safety Warnings (CRITICAL):
- Seizures: Levocarnitine has been reported to increase seizure frequency in patients with pre-existing seizure disorders.
- Drug Interactions: Warfarin/Anticoagulants (may increase INR/bleeding risk). Monitor Prothrombin Time (PT) closely.
- GI Effects: Nausea and “fishy body odor” (trimethylaminuria) may occur at high doses.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Sterile Injectables, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.