Lansoprazole Capsules
Healthy Inc is a specialized global supplier and exporter of essential gastrointestinal and anti-ulcer therapeutics. We provide high-purity Lansoprazole Capsules (15 mg / 30 mg), manufactured in WHO–GMP certified, advanced multi-particulate pelletization facilities. This “Rapid-Onset Proton Pump Inhibitor” is a massive-volume, essential export to primary care clinics, gastroenterology centers, and government health ministries in Africa, LATAM, the Middle East, and Southeast Asia, serving as a highly effective, globally trusted intervention for severe erosive esophagitis, Gastroesophageal Reflux Disease (GERD), and aggressive H. pylori eradication.
Product Overview
This formulation contains Lansoprazole, a potent substituted benzimidazole that provides profound, long-lasting inhibition of gastric acid secretion.
The “Rapid Relief & Eradication” Specialist:
- Mechanism (Irreversible Proton Pump Blockade): Lansoprazole is an inactive prodrug that is absorbed in the intestine and travels through the bloodstream to the highly acidic secretory canaliculi of the gastric parietal cells. There, it is rapidly converted into its active sulfonamide form. This active molecule covalently binds to the sulfhydryl groups of the H+/K+ ATPase enzyme system (the proton pump), completely and irreversibly shutting down the final, foundational step of gastric acid secretion.
- The H. Pylori Tri-Pack Champion: Lansoprazole is globally renowned as the preferred PPI backbone for “Triple Therapy” (Lansoprazole + Amoxicillin + Clarithromycin). By aggressively raising the pH of the stomach, it allows the co-administered antibiotics to survive in the gastric mucosa and physically destroy the ulcer-causing Helicobacter pylori bacteria.
- Rapid Onset Advantage: Clinical data frequently demonstrates that Lansoprazole provides faster relief of daytime and nighttime heartburn symptoms within the first few days of therapy compared to standard Omeprazole, making it a favorite for acute symptom management.
Product Composition & Strength
We supply this product as a Hard Gelatin Capsule containing Enteric-Coated Micro-Pellets, packed strictly in high-barrier Alu-Alu blister strips to ensure total moisture and light protection.
| Active Ingredient | Strength & Format | Primary Clinical Use |
|---|---|---|
| Lansoprazole USP/BP/Ph.Eur. | 15 mg (Enteric-Coated Pellets) | Maintenance healing of erosive esophagitis and mild GERD. |
| Lansoprazole USP/BP/Ph.Eur. | 30 mg (Enteric-Coated Pellets) | Standard Adult Dose for active PUD, severe erosive esophagitis, and H. Pylori protocols. |
| Excipients | Methacrylic Acid Copolymer / Hypromellose / Sucrose Spheres | Enteric Coating Polymer / Protective API Barriers / Inert Core |
*Pack Sizes: 10×10 Alu-Alu Blisters or specialized “H. Pylori Kit” multi-blister packaging for institutional tenders.
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Gastroenterology Distributors.
| HS Code | 3004.90.99 (Medicaments containing other active substances) |
| CAS Number | 103577-45-3 |
| Dosage Form | Hard Gelatin Capsule containing EC Pellets |
| Packaging | Alu-Alu Blister (CRITICAL). Lansoprazole is highly acid-labile and intensely sensitive to moisture. Standard PVC packaging will result in rapid API degradation, turning the pellets black. |
| Storage | Store strictly below 25°C in a dry place. Protect from Light and Moisture. |
| Certificates | WHO-GMP, COPP, Free Sale Certificate |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Fluid-Bed Enteric Engineering: Because Lansoprazole is instantly destroyed by stomach acid, our advanced fluid-bed coating machinery applies a highly precise methacrylic acid enteric-coating to the micro-pellets. This ensures the drug passes completely intact through the stomach and only dissolves upon reaching the alkaline pH of the duodenum, guaranteeing maximum systemic bioavailability.
- Two-Stage Dissolution Validation: Rigorous in vitro dissolution testing is performed via HPLC. The Acid Stage guarantees the enteric coating holds firm against simulated gastric fluid. The Buffer Stage guarantees rapid and total release of the API in simulated intestinal fluid.
Therapeutic Indications (Human Use)
Indicated for the comprehensive management of severe acid-related gastrointestinal disorders:
- Gastroesophageal Reflux Disease (GERD): Short-term treatment of symptomatic GERD and rapid healing of erosive esophagitis.
- Peptic Ulcer Disease (PUD): Healing and risk reduction of active duodenal ulcers and benign gastric ulcers, particularly those induced by chronic NSAID use.
- Helicobacter pylori Eradication: Used as the vital acid-suppressing component in dual or triple therapy with appropriate antibacterial regimens.
- Hypersecretory Conditions: Long-term management of Zollinger-Ellison syndrome.
Dosage & Administration
Recommended Dosage (Strictly as per Physician):
- Administration (TIMING IS CRITICAL): Must be taken orally, once daily, approximately 30 to 60 minutes BEFORE a meal (typically breakfast). The drug must be absorbed and present in the bloodstream when the parietal cells are stimulated to secrete acid by the consumption of food.
- Swallowing Protocol (CRITICAL): The capsule MUST be swallowed whole. For patients with severe dysphagia or feeding tubes, the capsule can be opened and the intact pellets sprinkled on soft food (like applesauce) or mixed with apple juice, but the pellets themselves must NEVER be chewed or crushed.
Safety Warnings (CRITICAL):
- Clostridioides difficile-Associated Diarrhea (CDAD): Profound, long-term acid suppression significantly alters the gut microbiome and increases the risk of severe intestinal infections, particularly C. difficile.
- Hypomagnesemia & Bone Fractures: Long-term PPI use (over 1 year) is associated with severe drops in blood magnesium levels and an increased risk of osteoporosis-related fractures of the hip, wrist, or spine. Routine supplementation and bone density monitoring may be required for chronic users.
- Vitamin B12 Deficiency: Daily treatment with any acid-suppressing medication over a prolonged period (greater than 3 years) can lead to malabsorption of cyanocobalamin (Vitamin B12), potentially causing irreversible neurological damage if unmonitored.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Gastroenterology Formulations, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government ulcer-eradication programs in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.