Gatifloxacin Ophthalmic Solution (0.3% w/v)

Healthy Inc is a specialized global supplier and exporter of advanced ophthalmology, anti-infectives, and targeted ocular therapeutics. We provide ultra-high-purity, kinetically stabilized Gatifloxacin Eye Drops, manufactured in WHO–GMP certified, high-precision sterile ophthalmic facilities. This “Fourth-Generation Fluoroquinolone” is a strategic export to eye hospitals, surgical centers, and government health ministries, serving as the globally preferred intervention for pre-operative prophylaxis and the treatment of severe bacterial conjunctivitis.

Product Overview

This formulation operates as a “Genetic Replication Disruptor.” As a 4th-generation agent, it is specifically engineered to bypass the resistance mechanisms that bacteria have developed against older quinolones like Ciprofloxacin.

• Mechanism 1 (Dual-Enzyme Inhibition): Gatifloxacin physically inhibits both DNA Gyrase and Topoisomerase IV. This “dual-target” approach makes it significantly harder for bacteria to develop resistance.

• Mechanism 2 (8-Methoxy Structure): It physically possesses an 8-methoxy group which enhances its activity against Gram-positive bacteria (like Staphylococcus and Streptococcus) while maintaining strong Gram-negative coverage.

• Mechanism 3 (Bactericidal Strike): By causing irreversible DNA damage and structural failure, it physically kills the pathogens responsible for vision-threatening infections.

Product Composition & Strength

We supply this product in a Sterile, Buffered, Isotonic Aqueous Solution, optimized for high ocular tolerance and rapid corneal flux.

Technical & Logistics Specifications

• HS Code: 3004.20.19 (Medicaments containing other antibiotics – Ophthalmic)

• CAS Number: 112811-59-3 (Gatifloxacin)

• Dosage Form: Sterile Eye Drops (Ophthalmic Solution)

• Packaging: Sterile LDPE Dropper Bottles (5ml). Our specialized ophthalmic packaging ensures 24-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Aseptic Filling Excellence: Our manufacturing process utilizes Class 100 (ISO 5) Sterile Filling Lines. This ensures the solution is 100% free from microbial contaminants, a non-negotiable requirement for post-surgical eyes.

• Precision Solubilization: We utilize Advanced Solubilization Techniques to ensure Gatifloxacin remains perfectly dissolved in the aqueous base, preventing precipitation and ensuring consistent dosing for every application.

Primary Indications

• Ophthalmology: Treatment of Bacterial Conjunctivitis caused by susceptible strains.

• Surgery: Pre-operative and post-operative Prophylaxis to prevent endophthalmitis.

• Specialized Care: Treatment of corneal ulcers where a 4th-generation quinolone is required due to suspected resistance.

Dosage & Administration

• Standard Regimen: Typically 1 drop in the affected eye(s) every 2 hours while awake (up to 8 times daily) for the first 2 days, then every 4 hours for the next 5 days.

• Administration: Apply to the conjunctival sac. To minimize systemic absorption, the patient should apply pressure to the tear duct for 1 minute after instillation.

• Duration: Typically used for 7 days.

Safety Warning: For Ophthalmic Use Only. Vision Warning: May cause temporary blurred vision; do not drive until vision is clear. Resistance Note: To prevent the development of resistant bacteria, the medication should be used exactly as prescribed for the full duration. Contraindication: Do not use if known hypersensitivity to fluoroquinolone antibiotics exists.

Global Export & Contract Manufacturing

Healthy Inc is a premier Ophthalmic and Anti-Infective Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume sterile antibiotic eye drops. Whether you are a Surgical Eye Hospital in the Middle East or a B2B Pharma Marketplace partner in Africa, the CIS, or LATAM, we ensure secure, WHO-GMP compliant delivery.