Erythromycin Estolate Oral Suspension (125 mg / 250 mg)
Healthy Inc is a specialized global supplier and exporter of advanced anti-infectives, pediatric medicine, and respiratory therapeutics. We provide ultra-high-purity, kinetically stabilized Erythromycin Estolate Suspension, manufactured in WHO–GMP certified, high-precision manufacturing facilities. This “Acid-Stable Macrolide” is a massive-volume strategic export to retail pharmacies, pediatric hospitals, and government health ministries, serving as the globally preferred intervention for patients with penicillin hypersensitivity and for the eradication of specific respiratory pathogens like Bordetella pertussis.
Product Overview
This formulation operates as a “Bacterial Protein Synthesis Inhibitor.” It physically enters the bacterial cell and shuts down the production of essential proteins, preventing the pathogen from replicating and surviving.
Mechanism 1 (50S Ribosomal Binding): Erythromycin physically binds to the 50S ribosomal subunit of susceptible bacteria.
Mechanism 2 (Translocation Blockade): It physically blocks the translocation step of protein synthesis. Without new proteins, the bacteria cannot physically maintain their structure or multiply.
Mechanism 3 (Acid Stability): The Estolate salt is physically unique because it is the most acid-stable form of Erythromycin. It passes through the stomach intact, ensuring maximum absorption in the small intestine.
Product Composition & Strength
We supply this product as a Micronized Homogeneous Suspension, ensuring maximum bioavailability and shelf-life stability in varied climates.
| Active Ingredient | Strength (per 5ml) | Primary Clinical Function |
| Erythromycin (as Estolate) IP/BP | 125 mg / 250 mg | The Antibiotic: Eradicates Gram-positive and specific Gram-negative pathogens. |
| Excipients | Sorbitol / Xanthan Gum | The Suspension Matrix: Ensures uniform drug delivery. |
| Flavoring | Cherry / Mixed Fruit / Banana | The Palatable Base: Essential for masking the natural bitterness. |
Technical & Logistics Specifications
HS Code: 3004.20.12 (Medicaments containing Macrolides)
CAS Number: 3521-62-8 (Erythromycin Estolate)
Dosage Form: Oral Liquid (Suspension)
Packaging: 60ml / 100ml Amber PET or Glass Bottles with child-resistant caps and measuring cups. Our specialized packaging ensures 36-month stability in Zone IVb tropical climates.
Manufacturing Authority & Compliance
Micronized Homogenization: Erythromycin Estolate particles are physically treated through High-Shear Homogenization to ensure they are perfectly suspended. This prevents “caking” at the bottom of the bottle and ensures an exact dose in every spoon.
Enhanced Bioavailability: Unlike the base form, the Estolate salt is physically absorbed regardless of food intake, making it more convenient for pediatric administration.
Aseptic Filling: We utilize Automated Liquid Filling Lines with 100% microbial testing to ensure total safety for infants and children.
Primary Indications
Pulmonology: First-line treatment for Pertussis (Whooping Cough) and Diphtheria.
ENT Medicine: Management of Streptococcal Pharyngitis and Tonsillitis in Penicillin-allergic patients.
Dermatology: Effective treatment for Acne Vulgaris and skin-structure infections (Erythrasma).
STIs: Treatment of Syphilis or Chlamydia during pregnancy when other drugs are contraindicated.
Dosage & Administration
Children: Typically 30 to 50 mg/kg/day in divided doses every 6 to 12 hours.
Adults: Typically 250 mg to 500 mg (5ml to 10ml) four times daily.
Administration: Because it is acid-stable, it can physically be taken with or without food.
Shake Well: The bottle must be physically shaken before each use to ensure uniform drug distribution.
Safety Warning: For Oral Use Only. Liver Note: Long-term use of the Estolate salt (more than 10 days) requires physical monitoring of liver function as it may cause cholestatic hepatitis in adults. Interaction Note: Erythromycin is a potent CYP3A4 inhibitor; consult a physician regarding concurrent medications. Contraindication: Do not use in patients with pre-existing liver disease or known hypersensitivity to Macrolides.
Global Export & Contract Manufacturing
Healthy Inc is a premier Anti-Infective and Pediatric Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume Macrolide suspensions. Whether you are a National Health Tender in Africa or a B2B Pharma Marketplace partner in the CIS, Middle East, or LATAM, we ensure secure, WHO-GMP compliant delivery.