Clobetasol Propionate Cream (0.05% w/w)
Healthy Inc is a specialized global supplier and exporter of advanced dermatology, immunology, and targeted corticosteroid therapeutics. We provide ultra-high-purity, kinetically stabilized Clobetasol Propionate Cream, manufactured in WHO–GMP certified, high-precision specialized topical facilities. This “Ultra-High Potency Corticosteroid” is a massive-volume strategic export to retail pharmacies, dermatology centers, and government health ministries, serving as the globally mandated intervention for severe, treatment-resistant inflammatory skin conditions.
Product Overview
This formulation operates as a “Nuclear Option” for skin inflammation. It physically enters the cell nucleus to shut down the genetic production of inflammatory markers, providing relief where other steroids cannot.
Mechanism 1 (Ultra-High Receptor Affinity): Clobetasol physically binds to Glucocorticoid Receptors with extreme intensity. This triggers the production of Lipocortins, which inhibit the enzyme Phospholipase A2, effectively cutting off the entire inflammatory cascade at the root.
Mechanism 2 (Vascular Constriction): It physically induces powerful Vasoconstriction. By narrowing the blood vessels in the dermis, it stops the leakage of fluid and immune cells into the skin, rapidly eliminating redness and swelling.
Mechanism 3 (Mitotic Inhibition): In conditions like Psoriasis, it physically slows down the excessive rate of skin cell division, preventing the formation of thick, scaly plaques.
Product Composition & Strength
We supply this product in a Smooth, Non-Greasy Vanishing Base, optimized for rapid absorption into thickened or leathery skin.
| Active Ingredient | Strength (w/w) | Primary Clinical Function |
| Clobetasol Propionate USP/BP | 0.05% | The Ultra-Potent Standard: The strongest topical steroid for severe dermatoses. |
| Excipients | White Soft Paraffin / Cetyl Alcohol | The Delivery Matrix: Engineered for maximum penetration into the epidermis. |
Technical & Logistics Specifications
HS Code: 3004.32.00 (Medicaments containing Adrenal Cortical Hormones)
CAS Number: 25122-46-7 (Clobetasol Propionate)
Dosage Form: Topical Cream (O/W Emulsion)
Packaging: Laminated Aluminum or Plastic Tubes (15g / 20g / 30g). Our high-barrier, UV-shielded tubes ensure 24-month stability in Zone IVb tropical climates.
Manufacturing Authority & Compliance
Hormonal Segregation Standards: Our manufacturing process utilizes Dedicated Ultra-High Potency Steroid Blocks with specialized air-handling units (AHUs) and terminal HEPA filtration to ensure zero cross-contamination, meeting the strictest international safety standards.
Micronization Excellence: We utilize Advanced Jet-Milling to ensure Clobetasol particles are ultra-fine. This ensures a smooth, non-irritating application—critical for patients with highly inflamed, sensitive skin.
Primary Indications
Dermatology: Treatment of Severe Psoriasis (excluding widespread plaque psoriasis) and recalcitrant Eczemas.
Immunology: Management of Lichen Planus, Discoid Lupus Erythematosus, and other conditions that do not respond to less potent steroids.
Specialized Care: Treatment of thick, leathery skin (Lichen Simplex Chronicus).
Dosage & Administration
Standard Regimen: Apply a thin layer to the affected area once or twice daily.
Strict Limit: Due to its extreme potency, total dosage should not exceed 50g per week.
Duration: Use should be limited to 2 consecutive weeks. Once the condition is under control, the patient must be tapered to a lower-potency steroid.
Safety Warning: External Use Only. Avoid contact with eyes. Steroid Awareness: Do not use on the face, groin, or underarms unless directed. Systemic Risk: Long-term use or use over large areas can cause HPA-axis suppression. Contraindication: Do not use on primary viral (Herpes), fungal, or bacterial skin infections without concurrent specific therapy.
Global Export & Contract Manufacturing
Healthy Inc is a premier Dermatology and Specialized Steroid Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume specialized topicals. Whether you are a Hospital Network in Africa or a B2B Pharma Marketplace partner in the CIS or LATAM, we ensure secure, WHO-GMP compliant delivery.
Commercial Inquiries:
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in