Calcium Carbonate & Calcitriol Softgel Capsules / Tablets

Healthy Inc is a specialized global supplier and exporter of advanced orthopedic, nephrology, and targeted endocrine therapeutics. We provide ultra-high-purity, kinetically optimized Calcium & Calcitriol Formulations, manufactured in WHO–GMP certified, high-precision facilities. This “Active Vitamin D3 & Elemental Calcium FDC” is a massive-volume, highly strategic export to orthopedic hospitals, dialysis centers, and government health ministries, serving as the globally mandated intervention for Post-menopausal Osteoporosis, Renal Osteodystrophy, and Hypocalcemia.

Product Overview

This formulation operates as a direct-entry skeletal restorer. By providing the body with Calcitriol—the final, most potent metabolite of Vitamin D—this product ensures maximum calcium transport regardless of the patient’s internal metabolic limitations.

• Mechanism 1 (The Active Ligand – Calcitriol): Calcitriol binds directly to Vitamin D Receptors (VDR) in the intestine. It triggers the active synthesis of Calbindin, a transport protein that physically “hand-carries” calcium ions from the gut into the bloodstream.

• Mechanism 2 (Bone Mineralization – Calcium Carbonate): We utilize high-elemental-strength Calcium Carbonate as the primary substrate. Once absorbed, it is deposited into the bone matrix by osteoblasts, increasing Bone Mineral Density (BMD) and preventing pathological fractures.

• Mechanism 3 (PTH Suppression): Calcitriol acts as a hormonal feedback signal to the parathyroid glands. It suppresses the secretion of Parathyroid Hormone (PTH), thereby preventing “Bone Resorption” (where the body steals calcium from the bones to feed the blood).

Product Composition & Strength

We supply this product as a Precision-Blended Softgel or Tablet, packed in high-barrier Alu-Alu or Blister strips to protect the light-sensitive Calcitriol.

Technical & Logistics Specifications

• HS Code: 3004.50.20 (Medicaments containing Vitamins and Minerals)

• CAS Numbers: 471-34-1 (Calcium Carbonate) / 32222-06-3 (Calcitriol)

• Dosage Form: Soft Gelatin Capsule (Recommended for absorption) or Film-Coated Tablet

• Packaging: Alu-Alu Blisters (STRICTLY MANDATORY). Calcitriol is extremely sensitive to light and oxidation. Alu-Alu packaging ensures 24-month potency in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Hormonal Containment: Calcitriol is a highly potent steroid hormone. Our facility utilizes Dedicated High-Containment Lines to ensure zero cross-contamination and 100% micro-dose accuracy (0.25 mcg is a microscopic amount that requires advanced mixing technology).

• Bioavailability Validation: We perform rigorous dissolution studies to ensure our Calcium + Calcitriol matches the pharmacokinetic profile of the originator brand (e.g., Rocaltrol-based combinations).

Primary Indications

• Orthopedics: Post-menopausal Osteoporosis and senile bone loss.

• Nephrology: Secondary Hyperparathyroidism and Renal Osteodystrophy in chronic kidney disease (CKD).

• Endocrinology: Hypocalcemia and Vitamin D-resistant rickets.

Dosage & Administration

• Standard Dosing: 1-2 units daily, or as directed by an orthopedic specialist.

• Administration: Best taken with food to enhance the absorption of the fat-soluble Calcitriol.

Safety Warning: Risk of Hypercalcemia. Patients must have their serum calcium and phosphorus levels monitored regularly. Contraindicated in patients with kidney stones or Vitamin D toxicity.

Global Export & Contract Manufacturing

Healthy Inc is a premier Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-potency Ortho-Nephro FDCs. Whether you are a Dialysis Center Buyer in Africa or a B2B Pharma Marketplace partner in the CIS, we ensure secure, WHO-GMP compliant delivery.