Healthy Inc > Products > Baclofen Tablets

Baclofen Tablets (10 mg / 20 mg)

Healthy Inc is a specialized global supplier and exporter of advanced neurology, rehabilitation, and targeted muscle-relaxant therapeutics. We provide ultra-high-purity, kinetically optimized Baclofen Tablets, manufactured in WHO–GMP certified, high-precision oral solid dosage facilities. This “Antispastic Agent” is a massive-volume strategic export to rehabilitation hospitals, neurology clinics, and government health ministries, serving as the globally mandated intervention for spasticity resulting from Multiple Sclerosis (MS), Spinal Cord Lesions, and Cerebral Palsy.

Product Overview

This formulation operates as a “Neural Damper.” Baclofen is a chemical analog of Gamma-Aminobutyric Acid (GABA), the primary inhibitory neurotransmitter in the human body. It is designed to physically suppress the overactive electrical signals in the spinal cord that cause muscles to lock, spasm, or cramp.

 

  • Mechanism 1 (GABA-B Receptor Agonism): Baclofen acts as a selective agonist at $GABA_B$ receptors in the spinal cord. This triggers the opening of potassium channels, which hyperpolarizes the nerve cells, making them less likely to “fire” an electrical impulse to the muscle.

     

  • Mechanism 2 (Pre-synaptic Inhibition): It inhibits the release of excitatory amino acids (like Glutamate and Aspartate) from the nerve terminals. By “turning down the volume” of these excitatory signals, it reduces the severity and frequency of painful muscle spasms.

     

  • Mechanism 3 (Monosynaptic & Polysynaptic Reflex Suppression): It targets both simple and complex reflex arcs in the spinal cord. This results in the relaxation of skeletal muscles without significantly reducing the overall muscle strength required for daily activities.

     

Product Composition & Strength

We supply this product as a Precision-Blended, High-Disintegration Tablet, packed in moisture-resistant Alu-PVC or Alu-Alu blister strips.

Active IngredientStrengthPrimary Clinical Function
Baclofen USP/BP/Ph.Eur.10 mgThe Standard Titration Unit: The primary dose used for gradual escalation to determine patient tolerance and efficacy.
Baclofen USP/BP/Ph.Eur.20 mgThe Maintenance Payload: High-potency dose for patients with severe spasticity from chronic spinal cord injuries.
ExcipientsProprietary MatrixRapid-Release System: Engineered to ensure a predictable $T_{max}$ (time to peak concentration) of 1 to 2 hours for fast relief.

Technical & Logistics Specifications

  • HS Code: 3004.90.99 (Medicaments containing other active substances – Neurology/Muscle Relaxants)

     

  • CAS Number: 1134-47-0 (Baclofen)

     

  • Dosage Form: Uncoated or Film-Coated Tablet (Scored for half-dosing)

  • Packaging: Alu-PVC or Alu-Alu Blisters. Protects the API from light and environmental humidity across Zone IVb tropical climates.

Manufacturing Authority & Compliance

  • Chiral Purity: Our manufacturing process focuses on absolute chemical stability, ensuring the Baclofen molecule remains potent and free from degradation products that could cause excessive sedation.

  • Content Uniformity: We utilize Advanced High-Shear Mixing to ensure every 10 mg or 20 mg tablet provides a consistent clinical response, critical for patients sensitive to neurological fluctuations.

Primary Indications

  • Neurology: Relief of spasticity in Multiple Sclerosis (MS) and other spinal cord diseases.

     

  • Rehabilitation: Management of muscle spasms resulting from spinal cord injuries, strokes, or traumatic brain injury.

     

  • Pediatrics: Specialized use in Cerebral Palsy to improve motor function (under specialist supervision).

     

Dosage & Administration

  • Standard Dosing: Usually started very low (e.g., 5 mg TID) and titrated slowly over several weeks to a maintenance dose of 40 mg to 80 mg daily.

     

  • The “Taper” Mandate (CRITICAL): Treatment must not be stopped abruptly. Sudden withdrawal can lead to hallucinations, seizures, and severe “rebound” spasticity. Doses must be tapered gradually over 1–2 weeks.

     

Safety Warning: May cause significant Drowsiness or dizziness. Avoid alcohol, as it increases the sedative effect. Use with caution in patients with renal impairment or a history of seizure disorders.

 

Global Export & Contract Manufacturing

Healthy Inc is a premier Neurology Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-precision Muscle Relaxants. Whether you are a Rehabilitation Center Buyer in Africa or a B2B Pharma Marketplace partner in the CIS, we ensure secure, WHO-GMP compliant delivery.

Add to cart