Anastrozole Tablets
Healthy Inc is a specialized global supplier and exporter of advanced oncology, endocrine, and targeted high-containment therapeutics. We provide ultra-high-purity, kinetically optimized Anastrozole Tablets, manufactured in WHO–GMP certified, strictly segregated high-containment oncology facilities. This “Aromatase Inhibitor” is a massive-volume strategic export to cancer hospitals, women’s health clinics, and government health ministries, serving as the globally preferred intervention for Hormone Receptor-Positive (ER+) Breast Cancer in post-menopausal women.
Product Overview
This formulation operates as a biochemical “Fuel Blockade.” In post-menopausal women, estrogen is no longer made in the ovaries but is converted from other hormones in fat and muscle tissues. Anastrozole stops this conversion, effectively starving estrogen-dependent tumors.
Mechanism 1 (Potent Aromatase Inhibition): Anastrozole is a highly selective inhibitor of the Aromatase Enzyme. This enzyme is responsible for converting androgens (like androstenedione) into estrogens (estradiol and estrone) in peripheral tissues.
Mechanism 2 (Near-Total Estrogen Suppression): A daily 1 mg dose reduces serum estradiol levels by approximately 95% to 98% in post-menopausal women. This “estrogen-deprivation” therapy significantly slows the growth and reduces the recurrence risk of breast cancer cells.
Mechanism 3 (The Selectivity Advantage): Unlike older steroids, Anastrozole is highly specific. Even at maximum suppression, it does not interfere with the production of other essential adrenal hormones like Cortisol or Aldosterone, meaning patients do not require hormone replacement therapy (HRT) while on treatment.
Technical & Logistics Specifications
HS Code: 3004.90.99 (Medicaments containing other active substances – Oncology/Antineoplastics)
CAS Number: 120511-73-1 (Anastrozole)
Dosage Form: Film-Coated Tablet
Packaging: Alu-Alu Blisters. Protects the sensitive API from light and environmental humidity; our moisture-lock packaging ensures 24-month stability in Zone IVb tropical climates.
Manufacturing Authority & Compliance
OEB 4 High-Containment: Anastrozole is a potent hormonal antineoplastic. Our facility utilizes Dedicated Oncology Blocks with negative pressure environments and primary containment to ensure zero cross-contamination and maximum safety for the production team.
Bioequivalence Integrity: We provide comprehensive dissolution and stability data to prove our generic matches the pharmacokinetic profile of the innovator brand (Arimidex), ensuring a predictable clinical outcome for long-term survivors.
Primary Indications
Oncology: Adjuvant treatment of post-menopausal women with hormone receptor-positive early breast cancer.
First-Line Therapy: Treatment of post-menopausal women with hormone receptor-positive or hormone receptor-unknown locally advanced or metastatic breast cancer.
Gynecology: Advanced management of endometriosis or infertility (off-label/specialist use).
Dosage & Administration
Standard Adult Dosing: 1 tablet (1 mg) once daily, taken at the same time every day.
Duration: Usually prescribed for 5 to 10 years to minimize the risk of cancer recurrence.
Administration: Can be taken with or without food.
Safety Warning: Bone Mineral Density (BMD). Because estrogen protects bones, Anastrozole can cause osteoporosis or fractures. Monitor for Joint Pain (Arthralgia) and cholesterol levels. Strictly contraindicated in pre-menopausal women and during pregnancy.
Global Export & Contract Manufacturing
Healthy Inc is a premier Oncology Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-end Endocrine Therapeutics. Whether you are a Cancer Hospital Network in Africa or a B2B Pharma Marketplace partner in Southeast Asia, we ensure secure, WHO-GMP compliant delivery.