Alpha Ketoanalogue Tablets (Sachet / Film-Coated Tablets)
Healthy Inc is a specialized global supplier and exporter of advanced nephrology, clinical nutrition, and targeted metabolic therapeutics. We provide ultra-high-purity, kinetically balanced Alpha Ketoanalogue Tablets, manufactured in WHO–GMP certified, high-precision specialized renal care facilities. This “Nitrogen-Free Amino Acid Supplement” is a premium strategic export to nephrology hospitals, dialysis centers, and government health ministries, serving as the globally mandated intervention for Chronic Kidney Disease (CKD) stages III, IV, and V.
Product Overview
This formulation operates as a “Nitrogen Recycler.” In kidney failure, the body cannot excrete urea (a byproduct of protein/nitrogen). Alpha Ketoanalogues allow the body to take that “waste” nitrogen and turn it back into useful muscle-building protein.
Mechanism 1 (Transamination – The Nitrogen Trap): Alpha Ketoanalogues are “precursors” to amino acids but lack the amino (nitrogen) group. Once ingested, they “trap” the excess nitrogen floating in the blood (residual urea) and convert themselves into Essential Amino Acids.
Mechanism 2 (Uremic Toxin Reduction): By recycling internal nitrogen, the production of new urea is significantly decreased. This lowers the Blood Urea Nitrogen (BUN) levels, physically reducing the “uremic” symptoms like nausea, itching, and fatigue.
Mechanism 3 (Renal Preservation): By allowing the patient to maintain a Very Low Protein Diet (VLPD) without suffering from muscle wasting (malnutrition), these tablets reduce the workload on the remaining functional nephrons, effectively delaying the initiation of dialysis.
Product Composition & Strength
We supply this product as a Multi-Mineral, Amino Acid Complex, carefully balanced to meet the Nutritional Requirements of Uremic Patients.
| Component (Active) | Amount per Tablet | Clinical Function |
| Alpha-Keto-Isoleucine / Leucine / Valine / Phenylalanine | Calcium Salts | The Protein Builders: Converted into essential amino acids using waste nitrogen. |
| Alpha-Hydroxy-Methionine | Calcium Salt | The Sulfur Source: Provides the essential hydroxy-analog of methionine. |
| L-Lysine / L-Threonine / L-Tryptophan | Acetate/Pure Form | Essential Amino Acids: Direct supplementation of AA that the body cannot synthesize. |
| L-Histidine / L-Tyrosine | Pure Form | Conditional Amino Acids: Critical for maintaining nitrogen balance in renal failure. |
| Calcium Content | ~50 mg (approx) | Phosphate Binder Support: Provides calcium which helps in managing hyperphosphatemia. |
Technical & Logistics Specifications
HS Code: 2922.49.90 (Oxygen-function amino-compounds – Ketoanalogues)
CAS Number: Multiple (Complex Blend)
Dosage Form: Film-Coated Tablet (Yellowish/White)
Packaging: Alu-Alu Blisters. Alpha Ketoanalogues are highly sensitive to atmospheric moisture; our high-barrier packaging ensures 24-month stability in Zone IVb tropical climates.
Manufacturing Authority & Compliance
Calcium-Salt Precision: Our manufacturing process focuses on the absolute purity of the Calcium Salts of the keto acids, ensuring consistent transamination rates and predictable reduction in BUN levels.
Nephro-Grade Purity: We utilize Dedicated Clinical Nutrition Production Blocks to ensure zero cross-contamination, meeting the strictest international standards for renal therapeutics.
Primary Indications
Nephrology: Prevention and treatment of damages due to faulty or deficient protein metabolism in Chronic Kidney Disease (CKD).
Renal Nutrition: Management of patients on a protein-restricted diet (0.4 to 0.6 g/kg/day).
Geriatrics: Management of malnutrition in elderly patients with declining renal function.
Dosage & Administration
Standard Adult Dosing: Usually 4 to 8 tablets three times daily (1 tablet per 5 kg body weight per day) during meals.
The “Meal” Rule (CRITICAL): These tablets must be taken during meals to ensure the keto acids are available to react with the amino acids released from food.
Administration: Swallow whole; do not chew.
Safety Warning: Hypercalcemia Risk. Because these are calcium salts, monitor blood calcium levels regularly. Do not use in patients with high calcium or those with disturbed amino acid metabolism. Ensure adequate calorie intake for the drug to work effectively.
Global Export & Contract Manufacturing
Healthy Inc is a premier Nephrology Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume Renal Supplements. Whether you are a National Dialysis Network in Africa or a B2B Pharma Marketplace partner in Southeast Asia, we ensure secure, WHO-GMP compliant delivery.