Deflazacort Suspension

Description

Deflazacort Oral Suspension (6 mg / 5 ml)

Healthy Inc is a specialized global supplier and exporter of advanced corticosteroids, pediatric neurology medicine, and immunology therapeutics. We provide ultra-high-purity, kinetically stabilized Deflazacort Suspension, manufactured in WHO–GMP certified, high-precision liquid manufacturing facilities. This “Oxazoline Derivative Corticosteroid” is a premium strategic export to pediatric hospitals, specialized neurology clinics, and government health ministries, serving as the globally preferred intervention for long-term inflammatory and autoimmune conditions where growth preservation is a priority.

Product Overview

This formulation operates as a “Targeted Immune Modulator.” It physically enters the cell to “switch off” the production of inflammatory chemicals while chemically minimizing the systemic side effects typically seen with older steroids.

• Mechanism 1 (Glucocorticoid Receptor Binding): Deflazacort is a prodrug that physically converts to its active form (21-desacetyl deflazacort). It physically binds to Glucocorticoid Receptors to inhibit the production of pro-inflammatory cytokines.

• Mechanism 2 (Selective Action): It physically demonstrates a higher ratio of anti-inflammatory to metabolic activity. This means it provides the same physical “healing” power with less chemical interference in bone and glucose metabolism.

• Mechanism 3 (Lymphocyte Inhibition): It physically reduces the number and activity of circulating lymphocytes, effectively “calming” an overactive immune system in cases of severe allergy or autoimmune disease.

Product Composition & Strength

We supply this product as a Sterile, Flavored, Micronized Suspension, optimized for precise pediatric dosing and high stability.

Technical & Logistics Specifications

• HS Code: 3004.32.00 (Medicaments containing adrenal cortical hormones)

• CAS Number: 14484-47-0 (Deflazacort)

• Dosage Form: Oral Liquid (Suspension)

• Packaging: 30ml / 60ml PET or Amber Glass Bottles with child-resistant caps and calibrated droppers/cups. Our specialized packaging ensures 36-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Micronized Uniformity: Our manufacturing process utilizes High-Shear Homogenization to ensure Deflazacort particles are perfectly micronized. This physically prevents “settling” at the bottom of the bottle, ensuring an exact 6mg dose in every 5ml.

• pH Stability Control: Deflazacort is physically sensitive to pH fluctuations. We utilize Precision Buffering to maintain the suspension at an optimal chemical state for maximum shelf-life.

• Aseptic Filling: We utilize Automated Liquid Filling Lines with 100% microbial testing to ensure total safety for immunocompromised pediatric patients.

Primary Indications

• Pediatric Neurology: First-line long-term therapy for Duchenne Muscular Dystrophy (DMD) to preserve muscle strength.

• Pulmonology: Management of Severe Chronic Asthma and respiratory allergies.

• Rheumatology: Treatment of Juvenile Idiopathic Arthritis and other autoimmune disorders.

• Dermatology: Management of severe inflammatory skin conditions (Psoriasis/Dermatitis).

Dosage & Administration

• Standard Regimen: Dosage is physically calculated based on the child’s body weight and the severity of the condition (typically 0.25 mg/kg to 1.5 mg/kg/day).

• Administration: Can be taken with or without food.

• Shake Well: The bottle must be physically shaken before use to ensure the active steroid is evenly distributed.

• Tapering: Clinical Note: Deflazacort should physically be tapered off gradually under medical supervision; do not stop abruptly.

Safety Warning: For Oral Use Only. Growth Note: While “bone-sparing,” long-term use still requires physical monitoring of height and weight in children. Immunity Note: May mask signs of infection; use with caution during active viral or bacterial outbreaks. Contraindication: Do not use in patients with systemic fungal infections or known hypersensitivity to Deflazacort.

Global Export & Contract Manufacturing

Healthy Inc is a premier Corticosteroid and Pediatric Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume steroid suspensions. Whether you are a National Neurology Center in the Middle East or a B2B Pharma Marketplace partner in the CIS, Africa, or SE Asia, we ensure secure, WHO-GMP compliant delivery.