Bethanecol Tablets

Description

Bethanechol Chloride Tablets (10 mg / 25 mg)

Healthy Inc is a specialized global supplier and exporter of advanced urology, gastroenterology, and targeted parasympathomimetic therapeutics. We provide ultra-high-purity, kinetically optimized Bethanechol Chloride Tablets, manufactured in WHO–GMP certified, high-precision oral solid dosage facilities. This “Cholinomimetic Agent” is a strategic specialty export to post-operative recovery units, urology clinics, and government health ministries, serving as the globally mandated intervention for acute non-obstructive urinary retention and neurogenic atony of the bladder.

Product Overview

This formulation operates as a biochemical “Ignition Switch” for the smooth muscles of the urinary and gastrointestinal tracts. Bethanechol is structurally related to acetylcholine but is engineered to resist destruction by the enzyme cholinesterase, ensuring a prolonged and effective therapeutic window.

• Mechanism 1 (Detrusor Muscle Activation): Bethanechol acts as a selective agonist at Muscarinic ($M_3$) Receptors in the bladder. This triggers the contraction of the Detrusor Muscle, which physically squeezes the bladder to initiate urination and empty the contents.

• Mechanism 2 (Trigone & Sphincter Relaxation): While it contracts the bladder body, it simultaneously assists in the functional relaxation of the urinary trigone and external sphincter, lowering the resistance to urine flow.

• Mechanism 3 (Gastrointestinal Motility): It increases the tone and peristaltic activity of the esophagus, stomach, and intestines. This makes it effective for treating “Lazy Bowel” or gastric atony where physical obstruction is not present.

Product Composition & Strength

We supply this product as a Precision-Blended, High-Bioavailability Tablet, packed in secure Alu-PVC or Alu-Alu blister strips.

Technical & Logistics Specifications

• HS Code: 3004.90.99 (Medicaments containing other active substances – Urology)

• CAS Number: 590-63-6 (Bethanechol) / 5593-73-7 (Bethanechol Chloride)

• Dosage Form: Uncoated or Film-Coated Tablet

• Packaging: Alu-Alu or Alu-PVC Blisters. Bethanechol is hygroscopic; our moisture-lock packaging ensures 24-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Cholinergic Precision: Our manufacturing process focuses on absolute chemical stability, ensuring that the Bethanechol Chloride does not degrade into inactive by-products, maintaining 100% potency until the expiration date.

• Bioequivalence Mastery: We provide comprehensive dissolution data to prove that our generic matches the pharmacokinetic profile of the innovator brand (Urecholine), ensuring a predictable clinical response.

Primary Indications

• Urology: Treatment of acute post-operative and post-partum non-obstructive (functional) urinary retention.

• Neurology: Management of neurogenic atony of the urinary bladder with retention.

• Gastroenterology: Adjunctive treatment for gastric atony or adynamic ileus (off-label/specialist use).

Dosage & Administration

• Standard Adult Dosing: 10 mg to 50 mg taken three to four times daily.

• The “Empty Stomach” Rule (CRITICAL): These tablets MUST be taken 1 hour before or 2 hours after meals. Taking it with food can cause severe nausea and vomiting due to excessive stimulation of the GI tract.

• Titration: Treatment is usually started with a low dose and increased until the patient can void urine naturally.

Safety Warning: Strictly contraindicated in patients with Physical Obstruction (e.g., kidney stones or enlarged prostate blocking flow), as forced contraction against an obstruction can cause bladder rupture. Avoid in patients with asthma, hyperthyroidism, or peptic ulcers.

Global Export & Contract Manufacturing

Healthy Inc is a premier Specialty Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-precision Parasympathomimetics. Whether you are a Surgical Hospital Network Buyer in Africa or a B2B Pharma Marketplace partner in the CIS, we ensure secure, WHO-GMP compliant delivery.